Aerobic Exercise Capacity In Mild-to-moderate Chronic Kidney Disease Is Maintained Over A 5 Year-period

2018 ◽  
Vol 50 (5S) ◽  
pp. 359
Author(s):  
Helena Wallin ◽  
Anette Rickenlund ◽  
Maria E. Eriksson ◽  
Eva Jansson ◽  
Carin Wallquist ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Aerobic Exercise ◽  
Exercise Capacity ◽  
Aerobic Exercise Capacity ◽  
Moderate Chronic Kidney Disease

scholarly journals Aerobic exercise capacity is maintained over a 5-year period in mild-to-moderate chronic kidney disease: A longitudinal study

2019 ◽  
Author(s):  
Helena Wallin ◽  
Eva Jansson ◽  
Carin Wallquist ◽  
Britta Hylander Rössner ◽  
Stefan H Jacobson ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Heart Rate ◽  
Renal Function ◽  
Kidney Disease ◽  
Haemoglobin Level ◽  
Aerobic Exercise ◽  
Exercise Capacity ◽  
Peak Heart Rate ◽  
Aerobic Exercise Capacity ◽  
Over Time

Abstract Background: Aerobic exercise capacity is reduced in non-dialysis chronic kidney disease (CKD), but little is known about the magnitude of changes in exercise capacity over time. In a 5-year-prospective study, we evaluated exercise capacity and known determinants of exercise capacity in patients with mild-to-moderate CKD attending a specialist nephrology clinic. Methods: We included 52 individuals with CKD stage 2–3 and 54 age- and sex-matched healthy controls. Peak workload was assessed through a maximal cycle exercise test. Muscle strength and lean body mass, cardiac function, vascular stiffness, renal function and haemoglobin level were evaluated. Tests were repeated after 5 years. Statistical analysis of longitudinal data was performed using linear mixed models. Results: Exercise capacity did not change significantly over time in either CKD individuals or controls, although the absolute workload levels were significantly lower in CKD individuals. Renal function decreased in both groups, with a faster decline in CKD (p = 0.05 between groups). Peak heart rate, haemoglobin level, handgrip strength, lean body mass and cardiovascular function did not decrease significantly over time in CKD individuals. Physical activity level increased over 5 years only in the CKD group. Conclusions: Aerobic exercise capacity and peak heart rate are maintained over 5 years in a group of patients with well-controlled CKD grade 2–3, despite a slight reduction in glomerular filtration rate, mirroring the lack of progression of cardiovascular and muscular dysfunction in this group.

scholarly journals Aerobic exercise capacity is maintained over a 5-year period in mild-to-moderate chronic kidney disease: a longitudinal study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Helena Wallin ◽  
Eva Jansson ◽  
Carin Wallquist ◽  
Britta Hylander Rössner ◽  
Stefan H. Jacobson ◽  
...  
Keyword(s):  
Physical Activity ◽  
Chronic Kidney Disease ◽  
Heart Rate ◽  
Renal Function ◽  
Aerobic Exercise ◽  
Exercise Capacity ◽  
Activity Level ◽  
Peak Heart Rate ◽  
Aerobic Exercise Capacity ◽  
Over Time

Abstract Background Aerobic exercise capacity is reduced in non-dialysis chronic kidney disease (CKD), but the magnitude of changes in exercise capacity over time is less known. Our main hypothesis was that aerobic ExCap would decline over 5 years in individuals with mild-to-moderate CKD along with a decline in renal function. A secondary hypothesis was that such a decline in ExCap would be associated with a decline in muscle strength, cardiovascular function and physical activity. Methods We performed a 5-year-prospective study on individuals with mild-to-moderate CKD, who were closely monitored at a nephrology clinic. Fiftytwo individuals with CKD stage 2–3 and 54 age- and sex-matched healthy controls were included. Peak workload was assessed through a maximal cycle exercise test. Muscle strength and lean body mass, cardiac function, vascular stiffness, self-reported physical activity level, renal function and haemoglobin level were evaluated. Tests were repeated after 5 years. Statistical analysis of longitudinal data was performed using linear mixed models. Results Exercise capacity did not change significantly over time in either the CKD group or controls, although the absolute workloads were significantly lower in the CKD group. Only in a CKD subgroup reporting low physical activity at baseline, exercise capacity declined. Renal function decreased in both groups, with a larger decline in CKD (p = 0.05 between groups). Peak heart rate, haemoglobin level, handgrip strength, lean body mass and cardiovascular function did not decrease significantly over time in CKD individuals. Conclusions On a group level, aerobic exercise capacity and peak heart rate were maintained over 5 years in patients with well-controlled mild-to-moderate CKD, despite a slight reduction in glomerular filtration rate. In line with the maintained exercise capacity, cardiovascular and muscular function were also preserved. In individuals with mild-to-moderate CKD, physical activity level at baseline seems to have a predictive value for exercise capacity at follow-up.

scholarly journals Aerobic exercise capacity is maintained over a 5-year period in mild-to-moderate chronic kidney disease: A longitudinal study

2020 ◽  
Author(s):  
Helena Wallin ◽  
Eva Jansson ◽  
Carin Wallquist ◽  
Britta Hylander Rössner ◽  
Stefan H Jacobson ◽  
...  
Keyword(s):  
Physical Activity ◽  
Chronic Kidney Disease ◽  
Heart Rate ◽  
Renal Function ◽  
Aerobic Exercise ◽  
Exercise Capacity ◽  
Activity Level ◽  
Peak Heart Rate ◽  
Aerobic Exercise Capacity ◽  
Over Time

Abstract Background: Aerobic exercise capacity is reduced in non-dialysis chronic kidney disease (CKD), but little is known about the magnitude of changes in exercise capacity over time. Our main hypothesis was that aerobic ExCap would decline over 5 years in individuals with mild-to-moderate CKD along with a decline in renal function. A secondary hypothesis was that such a decline in ExCap would be associated with a decline in muscle strength, cardiovascular function and physical activity. Methods: We performed a 5-year-prospective study on individuals with mild-to-moderate CKD, who were closely monitored at a nephrology clinic. Fiftytwo individuals with CKD stage 2–3 and 54 age- and sex-matched healthy controls were included. Peak workload was assessed through a maximal cycle exercise test. Muscle strength and lean body mass, cardiac function, vascular stiffness, self-reported physical activity level, renal function and haemoglobin level were evaluated. Tests were repeated after 5 years. Statistical analysis of longitudinal data was performed using linear mixed models.Results: Exercise capacity did not change significantly over time in either the CKD group or controls, although the absolute workloads were significantly lower in the CKD group. Only in a CKD subgroup reporting low physical activity at baseline, exercise capacity declined. Renal function decreased in both groups, with a faster decline in CKD (p = 0.05 between groups). Peak heart rate, haemoglobin level, handgrip strength, lean body mass and cardiovascular function did not decrease significantly over time in CKD individuals. Conclusions: On a group level, aerobic exercise capacity and peak heart rate were maintained over 5 years in patients with well-controlled mild-to-moderate CKD, despite a slight reduction in glomerular filtration rate, mirroring the lack of progression of cardiovascular and muscular dysfunction in this group. In patients with mild-to-moderate CKD, physical activity level at baseline seems to have a predictive value for exercise capacity at follow-up.

scholarly journals The association between race and income on risk of mortality in patients with moderate chronic kidney disease

2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Stacey A Fedewa ◽  
William M McClellan ◽  
Suzanne Judd ◽  
Orlando M Gutiérrez ◽  
Deidra C Crews
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Risk Of Mortality ◽  
Moderate Chronic Kidney Disease

Moderate Chronic Kidney Disease in Women Is Associated with Fracture Occurrence Independently of Osteoporosis

2010 ◽  
Vol 116 (3) ◽  
pp. c256-c262 ◽  
Author(s):  
Sinead Kinsella ◽  
Shawn Chavrimootoo ◽  
Michael G. Molloy ◽  
Joseph A. Eustace
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Moderate Chronic Kidney Disease
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