scholarly journals A Comparison of Techniques for Estimating and Detecting Changes in Skeletal Muscle Cross-Sectional Area

2019 ◽  
Vol 51 (Supplement) ◽  
pp. 945
Author(s):  
Johnathon H. Moore ◽  
Cody T. Haun ◽  
Emily L. Grandprey ◽  
Katelyn P. Joubert ◽  
Christopher G. Vann ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Comparison Of Techniques ◽  
Muscle Cross Sectional Area

Changes in skeletal muscle cross sectional area (CSA) in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with enzalutamide (ENZ).

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e16601-e16601 ◽  
Author(s):  
Sundhar Ramalingam ◽  
David J. Sermer ◽  
Rajan Gupta ◽  
Patrick Healy ◽  
Yuan Wu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Skeletal Muscle ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Castration Resistant Prostate Cancer ◽  
Cross Sectional ◽  
Castration Resistant ◽  
Muscle Cross Sectional Area

The skeletal muscle cross sectional area in long-term bisphosphonate users is smaller than that of bone mineral density-matched controls with increased serum pentosidine concentrations

Bone ◽  
2015 ◽  
Vol 75 ◽  
pp. 84-87 ◽  
Author(s):  
Shigeharu Uchiyama ◽  
Shota Ikegami ◽  
Mikio Kamimura ◽  
Keijiro Mukaiyama ◽  
Yukio Nakamura ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Skeletal Muscle ◽  
Bone Mineral ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Mineral Density ◽  
Cross Sectional ◽  
Muscle Cross Sectional Area

scholarly journals Genetic and environmental influences on skeletal muscle phenotypes as a function of age and sex in large, multigenerational families of African heritage

2007 ◽  
Vol 103 (4) ◽  
pp. 1121-1127 ◽  
Author(s):  
Steven J. Prior ◽  
Stephen M. Roth ◽  
Xiaojing Wang ◽  
Candace Kammerer ◽  
Iva Miljkovic-Gacic ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Lean Mass ◽  
Genetic Correlations ◽  
Cross Sectional Area ◽  
Calf Muscle ◽  
Sectional Area ◽  
Cross Sectional ◽  
African Heritage ◽  
Genetic Components ◽  
Muscle Cross Sectional Area

The aim of this study was to estimate the heritability of and environmental contributions to skeletal muscle phenotypes (appendicular lean mass and calf muscle cross-sectional area) in subjects of African descent and to determine whether heritability estimates are impacted by sex or age. Body composition was measured by dual-energy X-ray absorptiometry and computed tomography in 444 men and women aged 18 yr and older (mean: 43 yr) from eight large, multigenerational Afro-Caribbean families (family size range: 21–112). Using quantitative genetic methods, we estimated heritability and the association of anthropometric, lifestyle, and medical variables with skeletal muscle phenotypes. In the overall group, we estimated the heritability of lean mass and calf muscle cross-sectional area (h2 = 0.18–0.23, P < 0.01) and contribution of environmental factors to these phenotypes ( r2 = 0.27–0.55, P < 0.05). In our age-specific analysis, the heritability of leg lean mass was lower in older vs. younger individuals (h2 = 0.05 vs. 0.23, respectively, P = 0.1). Sex was a significant covariate in our models ( P < 0.001), although sex-specific differences in heritability varied depending on the lean mass phenotype analyzed. High genetic correlations (ρG = 0.69–0.81; P < 0.01) between different lean mass measures suggest these traits share a large proportion of genetic components. Our results demonstrate the heritability of skeletal muscle traits in individuals of African heritage and that heritability may differ as a function of sex and age. As the loss of skeletal muscle mass is related to metabolic abnormalities, disability, and mortality in older individuals, further research is warranted to identify specific genetic loci that contribute to these traits in general and in a sex- and age-specific manner.

A Comparison of Techniques for Estimating Training-Induced Changes in Muscle Cross-Sectional Area

2010 ◽  
Vol 24 (9) ◽  
pp. 2383-2389 ◽  
Author(s):  
Jason M DeFreitas ◽  
Travis W Beck ◽  
Matt S Stock ◽  
Michael A Dillon ◽  
Vanessa D Sherk ◽  
...  
Keyword(s):  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Comparison Of Techniques ◽  
Induced Changes ◽  
Muscle Cross Sectional Area

Effect of glycogen loading on skeletal muscle cross-sectional area and T2 relaxation time

2001 ◽  
Vol 173 (4) ◽  
pp. 385-390 ◽  
Author(s):  
A. T. Nygren ◽  
M. Karlsson ◽  
B. Norman ◽  
L. Kaijser
Keyword(s):  
Skeletal Muscle ◽  
Relaxation Time ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
T2 Relaxation Time ◽  
T2 Relaxation ◽  
Cross Sectional ◽  
Muscle Cross Sectional Area

Anthropometric Prediction of Skeletal Muscle Cross-sectional Area in Persons with Spinal Cord Injury

2016 ◽  
Vol 48 ◽  
pp. 894
Author(s):  
Rodney C. Wade ◽  
Ashraf S. Gorgey ◽  
Jennifer Hubert ◽  
Ryan Sumrell ◽  
Justin Bengel ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Cord Injury ◽  
Muscle Cross Sectional Area

Effect of acute head-down tilt on skeletal muscle cross-sectional area and proton transverse relaxation time

1996 ◽  
Vol 81 (4) ◽  
pp. 1572-1577 ◽  
Author(s):  
Michael S. Conley ◽  
Jeanne M. Foley ◽  
Lori L. Ploutz-Snyder ◽  
Ronald A. Meyer ◽  
Gary A. Dudley
Keyword(s):  
Skeletal Muscle ◽  
Relaxation Time ◽  
Transverse Relaxation Time ◽  
Cross Sectional Area ◽  
Neck Muscle ◽  
Upright Posture ◽  
Sectional Area ◽  
Cross Sectional ◽  
Transverse Relaxation ◽  
Muscle Cross Sectional Area

Conley, Michael S., Jeanne M. Foley, Lori L. Ploutz-Snyder, Ronald A. Meyer, and Gary A. Dudley. Effect of acute head-down tilt on skeletal muscle cross-sectional area and proton transverse relaxation time. J. Appl. Physiol.81(4): 1572–1577, 1996.—This study investigated changes in skeletal muscle cross-sectional area (CSA) evoked by fluid shifts that accompany short-term 6° head-down tilt (HDT) or horizontal bed rest, the time course of the resolution of these changes after resumption of upright posture, and the effect of altered muscle CSA, in the absence of increased contractile activity, on proton transverse relaxation time (T2). Average muscle CSA and T2 were determined by standard spin-echo magnetic resonance imaging. Analyses were performed on contiguous transaxial images of the neck and calf. After a day of normal activity, 24 h of HDT increased neck muscle CSA 19 ± 4 (SE)% ( P < 0.05) while calf muscle CSA decreased 14 ± 3% ( P < 0.05). The horizontal posture (12 h) induced about one-half of these responses: an 11 ± 2% ( P < 0.05) increase in neck muscle CSA and an 8 ± 2% decrease ( P < 0.05) in the calf. Within 2 h after resumption of upright posture, neck and calf muscle CSA returned to within 0.5% ( P > 0.05) of the values assessed after a day of normal activity, with most of the change occurring within the first 30 min. No further change in muscle CSA was observed through 6 h of upright posture. Despite these large alterations in muscle CSA, T2 was not altered by more than 1.1 ± 0.6% ( P > 0.05) and did not relate to muscle size. These results suggest that postural manipulations and subsequent fluid shifts modeling microgravity elicit marked changes in muscle size. Because these responses were not associated with alterations in muscle T2, it does not appear that simple movement of water into muscle can explain the contrast shift observed after exercise.

scholarly journals Overexpression of HSP10 in skeletal muscle of transgenic mice prevents the age-related fall in maximum tetanic force generation and muscle cross-sectional area

2010 ◽  
Vol 299 (1) ◽  
pp. R268-R276 ◽  
Author(s):  
Anna C. Kayani ◽  
Graeme L. Close ◽  
Wolfgang H. Dillmann ◽  
Ruben Mestril ◽  
Malcolm J. Jackson ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Atrophy ◽  
Cross Sectional Area ◽  
Force Generation ◽  
Sectional Area ◽  
Wild Type ◽  
Cross Sectional ◽  
Tetanic Force ◽  
Age Related ◽  
Muscle Cross Sectional Area

Skeletal muscle atrophy and weakness are major contributors to frailty and impact significantly on quality of life of older people. Muscle aging is characterized by a loss of maximum tetanic force (Po) generation, primarily due to muscle atrophy, to which mitochondrial dysfunction is hypothesized to contribute. We hypothesized that lifelong overexpression of the mitochondrial heat shock protein (HSP) HSP10 in muscle of mice would protect against development of these deficits. Po generation by extensor digitorum longus muscles of adult and old wild-type and HSP10-overexpressing mice was determined in situ. Muscles were subjected to damaging lengthening contractions, and force generation was remeasured at 3 h or 28 days to examine susceptibility to, and recovery from, damage, respectively. Muscles of old wild-type mice had a 23% deficit in Po generation and a 10% deficit in muscle cross-sectional area compared with muscles of adult wild-type mice. Overexpression of HSP10 prevented this age-related fall in Po generation and reduction in cross-sectional area observed in muscles of old wild-type mice. Additionally, overexpression of HSP10 protected against contraction-induced damage independent of age but did not improve recovery if damage occurred. Preservation of muscle force generation and CSA by HSP10 overexpression was associated with protection against the age-related accumulation of protein carbonyls. Data demonstrate that development of age-related muscle weakness may not be inevitable and show, for the first time, that lifelong overexpression of an HSP prevents the age-related loss of Po generation. These findings support the hypothesis that mitochondrial dysfunction is involved in the development of age-related muscle deficits.

OR37: Psoas Versus Whole L3 Skeletal Muscle Cross-Sectional Area: How Do They Relate?

2019 ◽  
Vol 38 ◽  
pp. S18
Author(s):  
K. Rollins ◽  
A. Gopinath ◽  
A. Awwad ◽  
I. Macdonald ◽  
D.N. Lobo
Keyword(s):  
Skeletal Muscle ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Muscle Cross Sectional Area

Panoramic ultrasonography is a valid method to measure changes in skeletal muscle cross-sectional area

2009 ◽  
Vol 108 (2) ◽  
pp. 273-279 ◽  
Author(s):  
Juha P. Ahtiainen ◽  
Merja Hoffren ◽  
Juha J. Hulmi ◽  
Mikko Pietikäinen ◽  
Antti A. Mero ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Valid Method ◽  
Muscle Cross Sectional Area
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