scholarly journals CORRIGENDUM: Clinical Presentation, Management and Outcome of Japanese Patients With Acute Myocardial Infarction in the Troponin Era – Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET) –

2015 ◽  
Vol 79 (7) ◽  
pp. 1643 ◽  
Author(s):  
Masaharu Ishihara ◽  
Masashi Fujino ◽  
Hisao Ogawa ◽  
Satoshi Yasuda ◽  
Teruo Noguchi ◽  
...  
2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
T Soeda ◽  
M Ishihara ◽  
F Fujino ◽  
H Ogawa ◽  
K Nakao ◽  
...  

Abstract Background Cardiac troponin (cTn) is the preferred biomarker for the diagnosis of acute myocardial infarction (AMI). Octogenarians who presented cTn positive AMI are not usually recruited in clinical trials. Therefore, their clinical characteristics and prognosis are rarely investigated. Objective To study the characteristics and prognosis in octogenarians who presented cTn positive AMI. Methods and results The Japanese registry of acute Myocardial INfarction diagnosed by Universal dEfiniTion (J-MINUET) is a prospective and multicenter registry. A total of 3,283 consecutive AMI patients who were diagnosed by cTn-based criteria were included. The patients were divided into non-octogenarians (n=2,593) and octogenarians (n=690). Compared with non- octogenarians, octogenarians showed significantly lower incidence of diabetes mellitus (37.6% and 31.9%, p=0.006) and dyslipidemia (53.6% and 45.6%, p<0.001), and significantly higher incidence of hypertension (64.1% and 75.3%, p<0.001) and chronic kidney disease (38.7% and 68.7%, p<0.001). Octogenarians showed significantly longer onset to door time (p<0.001) and longer door to device time (p<0.001). Though, compared with non-octogenarians, octogenarians showed lower peak CK (2,506 and 1,926, p<0.001), LVEF was significantly lower in octogenarians (54.6% and 52.6%, p=0.005). The presentation of AMI was different between the two group. The incidence of ST-segment elevation MI (STEMI) was 70.7% in non-octogenarians and 62.0% in octogenarians. Non-STEMI with CK elevation and without CK elevation were 16.2% and 13.1% in non- octogenarians, and 20.9% and 17.1% in octogenarians. In-hospital mortality was higher in octogenarians (4.7% and 13.2%, P<0.001). Especially, octogenarians with STEMI and non-STEMI with CK elevation showed the highest in-hospital mortality. And octogenarians without CK elevation showed similar in hospital mortality with non-octogenarians with STEMI (Figure). Conclusions J-MINUET showed the poor prognosis of octogenarians who were diagnosed as AMI based on cTn. Acknowledgement/Funding None


2001 ◽  
Vol 65 (8) ◽  
pp. 707-710
Author(s):  
Masami Kosuge ◽  
Kazuo Kimura ◽  
Toshiyuki Ishikawa ◽  
Tsutomu Endo ◽  
Makoto Shimizu ◽  
...  

2013 ◽  
Vol 77 (11) ◽  
pp. 2778-2785 ◽  
Author(s):  
Yasuhiro Morita ◽  
Kengo Maeda ◽  
Takahisa Kondo ◽  
Hideki Ishii ◽  
Kyoko Matsudaira ◽  
...  

2020 ◽  
Vol 61 (2) ◽  
pp. 215-222
Author(s):  
Satoru Suwa ◽  
Manabu Ogita ◽  
Hideki Ebina ◽  
Koichi Nakao ◽  
Yukio Ozaki ◽  
...  

2020 ◽  
Vol 75 (11) ◽  
pp. 223
Author(s):  
Pedro Gabriel Melo De Barros E Silva ◽  
Rodrigo Balada ◽  
Lucas Macedo ◽  
Thiago Macedo ◽  
Valter Furlan ◽  
...  

1982 ◽  
Vol 28 (10) ◽  
pp. 2152-2154 ◽  
Author(s):  
T Y Wang ◽  
J H Godfrey ◽  
L G Graham ◽  
M N Haddad ◽  
T C Hamilton

Abstract We immunochemically measured lactate dehydrogenase isoenzyme 1 (LD-1), calculated LD-1/LD ratios (% LD-1) for 122 specimens from 60 patients, and compared the results with those for the conventional cardiac profile and other findings such as clinical presentation and electrocardiogram. Results for LD-1 and % LD-1 could be classified into three groups: group I, with LD-1 less than 64 U/L; group II, with LD-1 greater than 64 U/L and % LD-1 between 17 and 37%; and group III, with LD-1 greater than 64 U/L and 5 LD-1 greater than 38%. These three groups correlated closely and consistently with three patients of cardiac profile, i.e., those of no acute myocardial infarct, myocardial ischemia, and acute myocardial infarct, respectively.


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