Laryngeal leiomyosarcoma

2000 ◽  
Vol 114 (5) ◽  
pp. 398-401 ◽  
Author(s):  
Gino Marioni ◽  
Giulia Bertino ◽  
Laura Mariuzzi ◽  
Anna Maria Bergamin-Bracale ◽  
Mattia Lombardo ◽  
...  

Abstract We report one case of leiomyosarcoma (LMS) of the larynx occurring in a patient with a history of immunosuppressive therapy, and offer a critical review of the literature. Epstein-Barr virus (EBV) genome was not identified in the neoplastic cells. The patient was treated with endoscopic resection and post-operative radiotherapy. Lung metastasis and thyroid infiltration became evident 14 months following treatment despite the absence of laryngeal recurrence. Progressive decline occurred and the patient died 15 months after diagnosis.

1996 ◽  
Vol 110 (11) ◽  
pp. 1075-1077 ◽  
Author(s):  
T. M. Jones ◽  
G. O. Owen ◽  
P. Morar

AbstractLife-threatening sequelae of Epstein-Barr virus infection are uncommon but may present as: local pharyngeal manifestations, splenic rupture, neurological and haematological disorders and altered hepatic function. We present a case of retropharyngeal haematoma with posterior hypopharyngeal wall necrosis, thrombocytopenia and altered clotting function as a result of Epstein-Barr virus infection. A review of the literature on retropharyngeal haematoma reveals this to be the only recorded case which can be directly attributed to Epstein-Barr virus infection.


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