Contrast-enhanced ultrasonography promotes differential diagnosis of ureteral neoplasms

2021 ◽  
pp. 20210078
Author(s):  
Yun Bai ◽  
Jun Lin ◽  
An Chen ◽  
Min Bai ◽  
Chunxiao Li ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Clinical Information ◽  
Benign Tumors ◽  
Ct Urography ◽  
Imaging Features ◽  
Urothelial Carcinomas ◽  
Pathological Result ◽  
Contrast Enhanced ◽  
Ureteral Neoplasms ◽  
Contrast Enhanced Ultrasonography

Objective: To compare the diagnostic value of contrast-enhanced ultrasonography (CEUS) with baseline ultrasound (B-US) in ureteral neoplasms. Methods: Retrospective analysis, comprising clinical presentation, image appearances, and diagnostic results on B-ultrasound and CEUS, considering pathological result as a gold-standard, was conducted on the clinical information of 39 patients with ureteral neoplasms. CT urography was used to detect and confirm the presence of ureteral neoplasms. Both B-ultrasound and CEUS investigations of those 39 patients under study were performed by a senior radiologist. Results: Pathological outcomes established 27 ureteral malignancies and 12 ureteral benignancies. Ureteral malignancies were observed to occur in older patients than benignancies (p = 0.002). Only the morphological indicator of the ureteric wall on B-ultrasound was different in ureteral malignancies and benignancies (p = 0.030). Tumors with hyperenhancement, larger width, and hyperenhanced ureteric wall were easily diagnosed as malignant on CEUS, whereas iso-/hypoenhanced, narrower, and iso-/hypoenhanced ureteric wall indicated benign tumors. Moreover, the lesion widths, enhanced morphologies of the ureteric wall, and the ureteral wall’s linear boundaries on CEUS were different between high- and low-stage ureteral urothelial carcinomas (p = 0.012, 0.002, 0.001, respectively). Conclusion: The display of microvessels in ureteral neoplasms was significantly enhanced by CEUS, thus contributing to the differential diagnosis of ureteral neoplasms while assisting the staging of ureteral urothelial carcinoma. Advances in knowledge: The imaging features of different ureteral neoplasms on CEUS were analyzed in this study. The diagnostic performances of CEUS and B-ultrasound in ureteral urothelial carcinomas were also explored.

scholarly journals Imaging Features of Renal Capsule Leiomyoma on Contrast-Enhanced Ultrasonography: A Case Report

2017 ◽  
Vol 33 (6) ◽  
pp. 514-519 ◽  
Author(s):  
José Andrade Moura Neto ◽  
Ana Flavia Perpétuo de Souza ◽  
José Hermógenes Rocco Suassuna ◽  
Luiz Carlos Aguiar Vaz ◽  
Nordeval Cavalcante Araújo
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant Recipient ◽  
Malignant Lesion ◽  
Immunosuppressive Drugs ◽  
Imaging Features ◽  
Diagnostic Challenge ◽  
Contrast Enhanced ◽  
Increased Risk ◽  
Contrast Enhanced Ultrasonography ◽  
Histopathologic Analysis

Leiomyomas of the kidney are rare, mostly occurring in adults as incidental findings, and are a diagnostic challenge. In a renal transplant recipient population, an increased risk of tumors is observed due to the effect of immunosuppressive drugs. A differential diagnosis between leiomyomas and other malignant lesions is not possible with current imaging methods. This report presents a case of a native kidney capsular leiomyoma in a kidney transplant recipient and highlights the features of computed tomography and contrast-enhanced ultrasound (CEUS), along with the histopathologic analysis. The CEUS and quantification studies are helpful in demonstrating the vascularization pattern of the renal capsular leiomyoma. This entity appearing with chronic kidney disease can resemble a renal cell carcinoma, in an otherwise healthy kidney. In this case, CEUS was useful for diagnosing the vascularization of the renal mass, although the pattern of intense vascularization could be diagnostically misleading, implying a malignant lesion. However, the pattern of enhancement due to CEUS showed no peculiarities that indicated histopathologic diagnosis.

scholarly journals Contrast-Enhanced Ultrasound in the Differential Diagnosis of Primary Thyroid Lymphoma and Nodular Hashimoto’s Thyroiditis in a Background of Heterogeneous Parenchyma

2021 ◽  
Vol 10 ◽  
Author(s):  
Lulu Yang ◽  
Haina Zhao ◽  
Yushuang He ◽  
Xianglan Zhu ◽  
Can Yue ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Hashimoto’S Thyroiditis ◽  
Diagnostic Performance ◽  
Roc Curves ◽  
Hashimoto's Thyroiditis ◽  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Thyroid Lymphoma ◽  
Contrast Enhanced ◽  
Primary Thyroid Lymphoma

ObjectiveTo investigate the diagnostic performance of contrast-enhanced ultrasound (CEUS) in the differentiation of primary thyroid lymphoma (PTL) and nodular Hashimoto’s thyroiditis (NHT) in patients with background of heterogeneous diffuse Hashimoto’s thyroiditis (HT).MethodsSixty HT patients with 64 thyroid nodules (31 PTL and 33 NHT) who had undergone CEUS examination were included in this study. With histopathological results as the reference, we evaluated the imaging features of each nodule on both conventional ultrasonography (US) and CEUS. Quantitative CEUS parameters including peak intensity (PI), time to peak (TTP), and area under the time–intensity curve (AUC) were gathered in the nodule and background parenchyma. The ratio indexes of theses parameters were calculated by the ratio of the lesion and the corresponding thyroid parenchyma. Logistic regression and receiver operating characteristic (ROC) curves analyses of valuable US indicators were further preformed to evaluate the diagnostic capability of CEUS in discrimination of PTL and NHT.ResultsAmong all the observed US imaging features and CEUS parameters, 10 indicators showed significant differences between PTL and NHT (all P < 0.05). All the significant indicators were ranked according to the odds ratios (ORs). Eight of them were CEUS associated including imaging features of enhancement pattern, degree, homogeneity, and quantification parameters of PI, AUC, ratios of PI, AUC, and TTP, while indicators on conventional US, including vascularity and size ranked the last two with ORs less than 3. The five single CEUS parameters showed good diagnostic performance in diagnosis of PTL with areas under ROC curves of 0.72–0.83 and accuracies of 70.3–75.0%. The combination of CEUS imaging features and the ratios of PI, AUC, and TTP demonstrated excellent diagnostic efficiency and achieved area under ROC curve of 0.92, which was significantly higher than any of the five single parameters (all P < 0.05), with a sensitivity of 83.9%, specificity of 87.9%, and accuracy of 85.9%.ConclusionsCEUS is an efficient diagnostic tool in the differential diagnosis of PTL and NHT for patients with diffuse HT. Conjoint analysis of CEUS imaging features and quantification parameters could improve the diagnostic values.

scholarly journals Adult pancreatoblastoma: a case report

2021 ◽  
Vol 49 (8) ◽  
pp. 030006052110395
Author(s):  
Jianchun Li ◽  
Chengzhong Peng ◽  
Xiaoming Fan ◽  
Ligang Wang ◽  
Jing Wang
Keyword(s):  
Preoperative Diagnosis ◽  
Paediatric Population ◽  
Emission Tomography ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Ultrasound Contrast ◽  
Positron Emission ◽  
Contrast Enhanced ◽  
Pancreatic Masses ◽  
Contrast Enhanced Ultrasonography

Pancreatoblastoma (PB) is a rare epithelial malignancy usually occurring in the paediatric population. Adult PB is rare, and its imaging findings are similar to those of other tumours, making preoperative diagnosis a considerable challenge. We report correlative ultrasound, contrast-enhanced ultrasonography, contrast-enhanced magnetic resonance imaging, and positron emission tomography-computed tomography findings in a 60-year-old woman with PB. PB often presents with uncommon imaging features and should be considered in the differential diagnosis of pancreatic masses. It is important for clinicians to be aware of these differences to provide effective treatment.

scholarly journals SIUMB recommendations for focal pancreatic lesions

2020 ◽  
Vol 23 (4) ◽  
pp. 599-606
Author(s):  
Mirko D’Onofrio ◽  
◽  
Ilario de Sio ◽  
Paoletta Mirk ◽  
Gianpaolo Vidili ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Medical Doctors ◽  
Contrast Enhanced ◽  
Focal Hepatic Lesions ◽  
Practical Guidelines ◽  
Contrast Enhanced Ultrasonography ◽  
Hepatic Lesions

Abstract Contrast-enhanced ultrasonography (CEUS) is increasingly being performed in Italy and Europe, particularly in the field of hepato-gastroenterology. Initially, it was mainly carried out to characterize focal hepatic lesions, but, since then, numerous studies have demonstrated its efficacy in the differential diagnosis of focal pancreatic pathologies (D’Onofrio et al. in Expert Rev Med Devices 7(2):257–273, 2010; Vidili et al. in J Ultrasound 22(1):41–51, 2019). The purpose of this paper is to provide Italian Medical Doctors with recommendations and thereby practical guidelines on the management of these patients. The present paper reports the final conclusions reached by the SIUMB guideline commission. This paper addresses particularly percutaneous ultrasound (US) examination (transabdominal US) and is drawn up specifically for publication.

Differential Diagnosis of Spine Tumors: My Favorite Mistake

2019 ◽  
Vol 23 (01) ◽  
pp. 026-035 ◽  
Author(s):  
Domenico Albano ◽  
Carmelo Messina ◽  
Salvatore Gitto ◽  
Olympia Papakonstantinou ◽  
Luca Sconfienza
Keyword(s):  
Differential Diagnosis ◽  
Pulse Sequences ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Imaging Features ◽  
Correct Interpretation ◽  
Benign Lesions ◽  
Contrast Enhanced ◽  
Robust Reliability

AbstractImaging has a pivotal role in the detection and characterization of spine bone tumors (SBTs), especially using magnetic resonance (MR) imaging and computed tomography (CT). Although MR performed with conventional pulse sequences has a robust reliability in the assessment of SBTs, some imaging features of benign lesions and malignancies overlap, making the differential diagnosis challenging. Several imaging tools are now available to perform a correct interpretation of images of SBTs including diffusion-weighted imaging, dynamic contrast-enhanced MR, Dixon sequences, and dual-energy CT. Nevertheless, strengths and weaknesses of imaging modalities should be kept in mind, and it is crucial to be aware of the pitfalls that can be encountered in daily clinical practice when dealing with these lesions. This review provides an overview on the main challenges encountered when dealing with SBTs, providing some tricks of the trade to avoid possible diagnostic traps.

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