IRAK Inhibitor Protects the Intestinal Tract of Necrotizing Enterocolitis by Inhibiting the Toll-Like Receptor (TLR) Inflammatory Signaling Pathway in Rats

Medical Science Monitor ◽

10.12659/msm.910327 ◽

2018 ◽

Vol 24 ◽

pp. 3366-3373 ◽

Author(s):

Yu Hou ◽

Xin Lu ◽

Yueju Zhang

Keyword(s):

Signaling Pathway ◽

Necrotizing Enterocolitis ◽

Intestinal Tract ◽

Toll Like Receptor ◽

Inflammatory Signaling

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Disruption of Tight Junction Barrier Function and Upregulation of Inflammatory Signaling Pathway in a Necrotizing Enterocolitis Mouse Model

The FASEB Journal ◽

10.1096/fasebj.29.1_supplement.265.5 ◽

2015 ◽

Vol 29 (S1) ◽

Author(s):

Srikanth Ravisankar ◽

Rodney Tatum ◽

Maja Herco ◽

Yan‐Hua Chen

Keyword(s):

Mouse Model ◽

Tight Junction ◽

Signaling Pathway ◽

Necrotizing Enterocolitis ◽

Barrier Function ◽

Inflammatory Signaling

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Semapimod Reduces Intestinal Cell Inflammatory Signaling by Blocking ATPase Activity in Toll-like Receptor-4 Chaperone gp96 to Reduce Phosphorylation of p38 MAPKinase in a Cell Line model for Necrotizing Enterocolitis

Journal of Surgical Research ◽

10.1016/j.jss.2013.11.624 ◽

2014 ◽

Vol 186 (2) ◽

pp. 624-625

Author(s):

A.Y. Lee ◽

J. Wang ◽

A. Grishin ◽

H.R. Ford

Keyword(s):

Atpase Activity ◽

Cell Line ◽

Necrotizing Enterocolitis ◽

Intestinal Cell ◽

Toll Like Receptor ◽

Inflammatory Signaling ◽

Toll Like Receptor 4 ◽

Cell Line Model ◽

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Toll-like receptor-6 (TLR6) deficient mice are protected from myocardial fibrosis induced by high fructose feeding through anti-oxidant and inflammatory signaling pathway

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2016.02.111 ◽

2016 ◽

Vol 473 (2) ◽

pp. 388-395 ◽

Author(s):

Yuan Zhang ◽

Yi Zhang

Keyword(s):

Signaling Pathway ◽

Myocardial Fibrosis ◽

Toll Like Receptor ◽

Inflammatory Signaling ◽

High Fructose ◽

Anti Oxidant ◽

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Norkurarinol Inhibits Toll-Like Receptor 3 (TLR3)-Mediated Pro-inflammatory Signaling Pathway and Rotavirus Replication

Journal of Pharmacological Sciences ◽

10.1254/jphs.11077fp ◽

2012 ◽

Vol 118 (2) ◽

pp. 161-170 ◽

Author(s):

Hyun-Mee Oh ◽

Seung Woong Lee ◽

Mi Hye Park ◽

Mi Hwa Kim ◽

Young Bae Ryu ◽

...

Keyword(s):

Signaling Pathway ◽

Toll Like Receptor ◽

Inflammatory Signaling

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Cotinine aggravates inflammatory response in thromboangiitis obliterans through TLR-4/MyD88/NF-κB inflammatory signaling pathway

International Angiology ◽

10.23736/s0392-9590.20.04327-8 ◽

2020 ◽

Vol 39 (3) ◽

Author(s):

Sen Shi ◽

Li Song ◽

Yong Liu ◽

Yanzheng He

Keyword(s):

Inflammatory Response ◽

Signaling Pathway ◽

Thromboangiitis Obliterans ◽

Inflammatory Signaling

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Faculty Opinions recommendation of TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1016387.200666 ◽

2003 ◽

Author(s):

David Underhill

Keyword(s):

Signaling Pathway ◽

Toll Like Receptor ◽

Toll Like Receptor 4

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Toll Like receptor 4 antagonist FP7 alleviates lipopolysaccharide‐induced septic shock via NF‐kB signaling pathway

Chemical Biology & Drug Design ◽

10.1111/cbdd.13837 ◽

2021 ◽

Author(s):

Chao Li ◽

Junhui Wang ◽

Mailiang Zhao ◽

Sheng Zhang ◽

Yanwei Zhang

Keyword(s):

Septic Shock ◽

Signaling Pathway ◽

Toll Like Receptor ◽

Toll Like Receptor 4

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Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells

Kidney & Blood Pressure Research ◽

10.1159/000447932 ◽

2016 ◽

Vol 41 (5) ◽

pp. 635-642 ◽

Author(s):

Tadaatsu Imaizumi ◽

Chikashi Yano ◽

Akiko Numata ◽

Koji Tsugawa ◽

Ryo Hayakari ◽

...

Keyword(s):

Signaling Pathways ◽

Mesangial Cells ◽

Type I Interferon ◽

Type I ◽

Toll Like Receptor ◽

Inflammatory Signaling ◽

Human Mesangial Cells

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Recently Discovered Oligosaccharide Inhibits Toll-Like Receptor 4 and Prevents Intestinal Stem Cell Apoptosis in Experimental Necrotizing Enterocolitis

Journal of the American College of Surgeons ◽

10.1016/j.jamcollsurg.2016.06.168 ◽

2016 ◽

Vol 223 (4) ◽

pp. S86

Author(s):

Laura Y. Martin ◽

Chhinder P. Sodhi ◽

Hongpeng Jia ◽

Yukihiro Yamaguchi ◽

Misty Good ◽

...

Keyword(s):

Stem Cell ◽

Necrotizing Enterocolitis ◽

Cell Apoptosis ◽

Intestinal Stem Cell ◽

Toll Like Receptor ◽

Toll Like Receptor 4

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Ginsenoside Ro, an oleanolic saponin of Panax ginseng, exerts anti-inflammatory effect by direct inhibiting toll like receptor 4 signaling pathway

Journal of Ginseng Research ◽

10.1016/j.jgr.2021.05.011 ◽

2021 ◽

Author(s):

Hong-Lin Xu ◽

Guang-Hong Chen ◽

Yu-Ting Wu ◽

Ling-Peng Xie ◽

Zhang-Bin Tan ◽

...

Keyword(s):

Signaling Pathway ◽

Panax Ginseng ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Anti Inflammatory ◽

Inflammatory Effect

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