scholarly journals Correlation between Serum Uric Acid Level and Microalbuminuria in Type-2 Diabetic Nephropathy

2017 ◽  
Vol 33 (6) ◽  
Author(s):  
Hina Latif ◽  
Adil Iqbal ◽  
Rabia Rathore ◽  
Nasir Farooq Butt
Keyword(s):  
Uric Acid ◽  
Diabetic Nephropathy ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Type 2 Diabetic

Effect of Lovastatin Therapy and Withdrawal on Serum Uric Acid Level in People With Type 2 Diabetic Nephropathy

2012 ◽  
Vol 31 (4) ◽  
pp. 353-363 ◽  
Author(s):  
Nariman Nezami ◽  
Javid Safa ◽  
Behzad Salari ◽  
Sona Ghorashi ◽  
Khashayar Khosraviani ◽  
...  
Keyword(s):  
Uric Acid ◽  
Diabetic Nephropathy ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Type 2 Diabetic

scholarly journals Analysis of Serum Uric Acid Level in Patients with and without Diabetic Nephropathy

2020 ◽  
Vol 27 (1) ◽  
Author(s):  
Erika Rosaria Simbolon ◽  
Suci Aprianti ◽  
Nurahmi Nurahmi ◽  
Liong Boy Kuniawan
Keyword(s):  
Uric Acid ◽  
Diabetic Nephropathy ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Microvascular Complications ◽  
Serum Levels ◽  
Significant Difference

Diabetic nephropathy is one of the microvascular complications in type 2 Diabetes Mellitus (DM). Diagnosis of diabeticnephropathy is based on any history of DM, a decrease in Glomerular Estimation Filtrate Rate (eGFR) using the CKD-Epiformula, and albuminuria. The role of serum uric acid level in diabetic nephropathy remains an ongoing debate. Serum uricacid levels may be the cause or the result of diabetic nephropathy. This study aimed to analyze serum uric acid levels inpatients with and without diabetic nephropathy and determine its correlation with diabetic nephropathy. This study wasperformed at Dr. Wahidin Sudirohusodo Hospital, Makassar, by taking the data from the medical record of type 2 DMpatients from January to April 2018. Fifty-nine patients with diabetic nephropathy and 150 patients without diabeticnephropathy participated in this study. An independent T-test and Pearson's correlation test were used for statisticalanalysis. There was a significant difference in uric acid level between patients with and without diabetic nephropathy(9.57±3.42 mg/dL vs. 6.41±2.86 mg/dL, p < 0.001). There was significant correlation between uric acid serum levels with urea(p < 0.001, r=0.585), creatinine (p<0.001, r=0.413) and eGFR (p < 0.001, r=-0.525) in patients with diabetic nephropathy. Uricacid levels in patients with diabetic nephropathy were higher than patients without diabetic nephropathy. Higher levels ofurea and the serum creatinine led to higher levels of serum uric acid. Contrastingly, a lower eGFR rate led to higher levels ofuric acid.

scholarly journals Serum uric acid level is associated with type 2 diabetes mellitus and diabetic regulation

2018 ◽  
Vol 1 (4) ◽  
pp. 134-138 ◽  
Author(s):  
Burcin Meryem Atak ◽  
Tuba Taslamacioglu Duman ◽  
Mehmet Zahid Kocak ◽  
Haluk Savli
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level

scholarly journals Serum uric acid level in type 2 diabetes mellitus

2019 ◽  
Vol 6 (4) ◽  
pp. 1265
Author(s):  
D. Vasantha Kalyani ◽  
M. Ilamaran ◽  
P. Suresh Kumar ◽  
Saranya Nagalingam
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
The Mean ◽  
Artery Disease

Background: Diabetes mellitus is the most important risk factor associated with two to four fold increased incidence of coronary artery disease. The major risk factors for CAD are hypercholesterolemia, hypertension, diabetes mellitus, and cigarette smoking Objectives: To study the level of serum uric acid in type 2 diabetes mellitus and the correlation between elevated serum uric acid level and the component of metabolic syndrome like obesity, hypertension, dyslipidemia.Methods: The study was done as descriptive analytical study among the diabetic patients in a tertiary care setting during the period January 2018 to February 2019. The inclusion and exclusion criteria were clearly defined and the study participants were recruited for the study after getting the informed consent. The socio demographic profile, clinical and laboratory data were collected from the blood sample obtained from the patients with the standardized procedures. Data was entered in Microsoft excel spread sheet and analyzed statistically using SPSS statistical software. Student ‘t’ test and Chi-square test values were applied for significance.Results: Serum uric acid in the study population and control varied from 3.0 to 8.1 and 2.7 to 5.5 mg/dl respectively. The mean and standard deviation of uric acid among cases was 5.08±1.42 while in control it was 3.55±0.62 respectively. The serum uric acid level of diabetics was very much elevated compare with controls and it was highly significant. Significant correlation was noticed between serum uric acid and BMI as well as WHR. Elevated uric acid levels were significantly noticed among those with hypertension, dyslipidemia, coronary artery disease and chronicity of the diabetes.Conclusions: Uric acid was significantly elevated in diabetic population and the mean value of serum uric acid level was higher in longer duration of diabetes, hypertension, dyslipidemia, central obesity which are the components of metabolic syndrome.

scholarly journals STUDY OF SERUM URIC ACID LEVEL IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

2021 ◽  
pp. 36-38
Author(s):  
Rohit Mathew ◽  
Aswathy Joseph
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Life Style Changes

BACKGROUND:Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. AIM:To evaluate the serum uric acid level in patients with type 2 Diabetes mellitus. MATERIALS AND METHODS:It was a prospective observational study conducted on 100 patients attending Medicine Department of Jhalawar Medical College, Jhalawar, Rajasthan. The study was done to assess the uric acid status in patients with diabetes mellitus and to find out its association with Age, Gender, Body Mass Index (BMI), Waist Hip Ratio (WHR), Dyslipidemia and Hypertension. Relevant history, vitals, clinical examination and laboratory investigations were done and recorded. RESULTS:This study evaluated the level of serum uric acid in Type 2 diabetes mellitus patients and confirmed there significantly high prevalence of hyperuricemia among type 2 diabetes subjects and increased association with increasing age, BMI, WHR, Dyslipidemia, Hypertension and female sex. CONCLUSION: Patients with Poor metabolic control and longer duration of diabetes were more susceptible to develop various complications including hyperuricemia. Early diagnosis and control of Diabetes Mellitus and its complications is indicated and potential therapeutic approaches (therapeutic life style changes and pharmacotherapy) should be initiated.

CORRELATION OF SERUM URIC ACID LEVEL WITH GLYCAEMIC STATUS IN TYPE 2 DIABETES MELLITUS PATIENTS IN DARBHANGA

2021 ◽  
pp. 68-70
Author(s):  
Mritunjay Kumar ◽  
Sheela Kumari ◽  
Debarshi Jana
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Blood Glucose ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level

Objectives : Our study was to detect the correlation of serum uric acid level with glycaemic status and with lipid prole. And also evaluate the various biochemical parameters, anthropometric measurements, blood pressure, serum uric acid level and associated factors. Methods: A 100 subjects with type 2 diabetes mellitus as a case and 100 subjects with non diabetics as control with age group greater than 40 years were enrolled in this study. A detail history, dietary pattern, clinical examination and relevant investigation were performed. Anthropometric examination like as measurement of BMI, measurement of waist-hip ratio and biochemical investigations like as blood glucose, serum HbA1c estimation, serum uric acid and serum lipid prole were performed to all subjects. Results : Data was analyzed by using SPSS software. Mean±SD was observed. P value was taken ≤0.05 for signicant differences. Conclusion : Type 2 diabetes mellitus patients is a strong negative correlation between blood glucose level and serum uric acid level. So that serum uric acid can be used as an important parameter to assess future cardiovascular risk in a type 2 diabetes mellitus patient.

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