Case Report: Inflammatory myofibroblastic tumor causes formation of an ileal conglomerate in a patient previously treated for Wilms’ tumor

Introduction: Inflammatory myofibroblastic tumors (IMTs) are uncommon mesenchymal lesions classified by WHO as neoplasms of uncertain behavior. Morphologically, IMTs are composed of proliferating spindled myofibroblastic cells accompanied by a marked - usually chronic - inflammatory infiltrate. The etiology is unknown, but several theories have been suggested, including an association with Wilms’ tumor. IMTs are rarely diagnosed in adults and have been reported in various organs. IMTs are considered benign but with a potential to recur at their primary site. Case report: A 44-year-old female experienced intermittent severe abdominal pain, loose stools and a visible abdominal bulge. In early childhood the patient had been treated for a Wilms’ tumor. At admission Meckel’s diverticulitis was suspected, but during surgery a tumor in the terminal ileum, creating a conglomerate of small intestinal loops, was observed and completely resected. The pathology report characterized the tumor as a histologically benign inflammatory myofibroblastic tumor. Postoperatively, the patient experienced several complications including an anastomotic leakage and subsequent formation of an abscess and transcutaneous fistula. Discussion: IMTs rarely arise in the small intestine, and to our knowledge the manifestation of a small intestine conglomerate has not been described previously. Making the diagnosis is difficult, and numerous differential diagnoses were possible in this case. Approximately 8-25% of IMTs in the gastrointestinal tract recur locally. Complete surgical resection is the treatment of choice, and re-excision is the preferred therapy for local recurrence. To our knowledge, no guidelines concerning follow-ups are available. Conclusion: IMTs in the terminal ileum can mimic Meckel’s diverticulitis and present with symptoms of obstructive ileus due to the formation of a conglomerate of small intestinal loops. Furthermore, IMTs should be considered as a diagnostic possibility in patients with a past medical history of Wilms’ tumor.

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Arteriovenous uterine malformation: case report

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20196056 ◽

2019 ◽

Vol 9 (1) ◽

pp. 409

Author(s):

Raúl D. Lara Sánchez ◽

Alexander J. Rafaelano Miranda ◽

Sara E. Hernandez Flores ◽

Tania P. Alvarez ◽

Jose M. Bizuet Cabrera ◽

...

Keyword(s):

Case Report ◽

Heavy Menstrual Bleeding ◽

Menstrual Bleeding ◽

Ultrasound Finding ◽

Pathology Report ◽

Uterine Malformation ◽

History Of

The case of a 49-year-old patient is reported, with a particular history of obstetric risk, who presented with severe transvaginal hemorrhage, was performed doppler arteriography and ultrasound, finding data suggestive of arteriovenous uterine malformation, surgery was decided due to heavy menstrual bleeding with anemia, the pathology report shows characteristics of an arteriovenous uterine malformation.

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Atresia coli in a Japanese black calf diagnosed by a barium sulphate enema contrast radiograph in the standing position: a case report

Veterinární Medicína ◽

10.17221/6267-vetmed ◽

2012 ◽

Vol 57 (No. 7) ◽

pp. 376-379

Author(s):

K. Abouelnasr ◽

M. Ishii ◽

H. Inokuma ◽

Y. Kobayashi ◽

K. Lee ◽

...

Keyword(s):

Small Intestine ◽

Case Report ◽

Abdominal Distension ◽

Standing Position ◽

Barium Sulphate ◽

Radiographic Examination ◽

Anal Opening ◽

Old Japanese ◽

History Of ◽

Colon And Rectum

A three day-old Japanese black calf was admitted with a history of abdominal distension and absence of defecation. Dilated loops of the small intestine and hypoplasia of the colon and rectum was observed upon a contrast radiographic examination in the standing position. At necropsy atresia coli with undeveloped rectum and patent anal opening was found. We conclude that a contrast radiograph in the standing position is useful for diagnosing atresia coli in such cases.  

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Primary Adenosquamous Cell Carcinoma of the Ileum in a Dog

Veterinary Sciences ◽

10.3390/vetsci7040155 ◽

2020 ◽

Vol 7 (4) ◽

pp. 155

Author(s):

Masashi Yuki ◽

Roka Shimada ◽

Tetsuo Omachi

Keyword(s):

Small Intestine ◽

Case Report ◽

Cell Carcinoma ◽

Surgical Resection ◽

Clinical Course ◽

Mass Lesion ◽

Abdominal Radiography ◽

First Case ◽

History Of

A 9-year-old male, castrated Chihuahua was examined because of a 7-day history of intermittent vomiting. A mass in the small intestine was identified on abdominal radiography and ultrasonography. Laparotomy revealed a mass lesion originating in the ileum, and surgical resection was performed. The mass was histologically diagnosed as adenosquamous cell carcinoma. Chemotherapy with carboplatin was initiated, but the dog was suspected to have experienced recurrence 13 months after surgery and died 3 months later. To our knowledge, this is the first case report to describe the clinical course of adenosquamous cell carcinoma in the small intestine of a dog.

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Multiple Spinal Cavernous Malformations with Atypical Phenotype after Prior Irradiation: Case Report

Neurosurgery ◽

10.1227/01.neu.0000143618.88015.dd ◽

2004 ◽

Vol 55 (6) ◽

pp. E1435-E1439 ◽

Cited By ~ 23

Author(s):

Pascal Jabbour ◽

Judith Gault ◽

Steven E. Murk ◽

Issam A. Awad

Keyword(s):

Magnetic Resonance Imaging ◽

Case Report ◽

Magnetic Resonance ◽

Wilms Tumor ◽

Incidental Finding ◽

Resonance Imaging ◽

Cavernous Malformations ◽

Drop Metastasis ◽

History Of ◽

Radiation Induced

Abstract OBJECTIVE AND IMPORTANCE: This is the first reported case of histologically proven multiple spinal cavernous malformations (CMs) associated with previous irradiation. There are only two cases reported in the literature of solitary spinal CM after irradiation. In addition, the lesions in our patient had an atypical magnetic resonance imaging appearance mimicking intraspinal drop metastasis. CLINICAL PRESENTATION: A 33-year-old man had an incidental finding of multiple enhancing intraspinal lesions as revealed by magnetic resonance imaging during staging tests for hepatocellular carcinoma. He had a history of Wilms' tumor at a young age with irradiation to the abdomen and pelvis. His family history included a paternal cousin with multiple cerebral CMs. The diagnosis of spinal drop metastasis was made, and further intervention was undertaken for confirmation. INTERVENTION: The patient underwent a lumbar laminectomy with durotomy and excision of two of the lesions. Macroscopic analysis revealed mulberry-like appearance with nerve root involvement, and pathological analysis confirmed the diagnosis of CM. Genetic testing of the patient and his affected cousin was negative for the CCM1 gene. CONCLUSION: The occurrence of multiple spinal lesions in the context of known neoplasia indicates a diagnosis of metastasis. Spinal CMs were not suspected preoperatively because of the atypical appearance revealed by magnetic resonance imaging scans, with uniform contrast enhancement and absence of hemosiderin rim. This case report is discussed relative to previous literature regarding radiation-induced CMs and other known causes of the disease.

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Inflammatory myofibroblastic tumor of the small intestine with intussusception in a child: Case report and literature review

Journal of Pediatric Surgery Case Reports ◽

10.1016/j.epsc.2020.101423 ◽

2020 ◽

Vol 56 ◽

pp. 101423

Author(s):

Rina Harada ◽

Masahiro Ohtaki ◽

Naoki Hashizume ◽

Akihiro Takeshi ◽

Eishiro Murai ◽

...

Keyword(s):

Small Intestine ◽

Case Report ◽

Literature Review ◽

Inflammatory Myofibroblastic Tumor

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Intestinal intussusception and occlusion caused by small bowel polyps in the Peutz-Jeghers syndrome. Management by combined intraoperative enteroscopy and resection through minimal enterostomy: case report

Revista do Hospital das Clínicas ◽

10.1590/s0041-87812000000600005 ◽

2000 ◽

Vol 55 (6) ◽

pp. 219-224 ◽

Cited By ~ 3

Author(s):

Joaquim J. Gama-Rodrigues ◽

José Hyppolito da Silva ◽

Adilson A. Aisaka ◽

Ricardo Jureidini ◽

Renato Falci Júnior ◽

...

Keyword(s):

Small Intestine ◽

Case Report ◽

Surgical Intervention ◽

Intestinal Resection ◽

Hereditary Disease ◽

Secondary Complications ◽

Surgical Interventions ◽

History Of ◽

Peutz Jeghers Syndrome

The Peutz-Jeghers syndrome is a hereditary disease that requires frequent endoscopic and surgical intervention, leading to secondary complications such as short bowel syndrome. CASE REPORT: This paper reports on a 15-year-old male patient with a family history of the disease, who underwent surgery for treatment of an intestinal occlusion due to a small intestine intussusception. DISCUSSION: An intra-operative fiberscopic procedure was included for the detection and treatment of numerous polyps distributed along the small intestine. Enterotomy was performed to treat only the larger polyps, therefore limiting the intestinal resection to smaller segments. The postoperative follow-up was uneventful. CONCLUSION: We point out the importance of conservative treatment for patients with this syndrome, especially those who will undergo repeated surgical interventions because of clinical manifestation while they are still young.

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Oesophageal pseudotumor: a case report

International Surgery Journal ◽

10.18203/2349-2902.isj20171162 ◽

2017 ◽

Vol 4 (4) ◽

pp. 1469

Author(s):

Sreejayan M. P. ◽

Arun S.

Keyword(s):

Case Report ◽

Soft Tissue ◽

Inflammatory Myofibroblastic Tumor ◽

Inflammatory Pseudotumor ◽

Soft Tissue Density ◽

Lower Esophagus ◽

Immunoglobulin G4 ◽

Related Disease ◽

Right Thoracotomy ◽

History Of

Inflammatory pseudo tumor (IPT) also known as inflammatory myofibroblastic tumor (IMT) is a tumor like mass of inflammatory origin. It is a pseudo sarcomatous lesion that has been reported most commonly in liver, followed by lung, mesentery and omentum but very rarely seen in esophagus. Proliferation of myofibroblastic cells is more in IMT. In IPT it is more of an inflammatory reactive or regenerative entity and has an overlapping with immunoglobulin G4-related disease. Lesion often mimics malignancy. A 20 year old male patient with history of dysphagia, more for liquids, underwent CT thorax, showing dilated oesophagus, with a moderately contrast enhancing eccentric soft tissue density lesion involving mid and lower esophagus extending for a length of 6cm. Patient underwent right thoracotomy, and a 5x3x3cm hard lesion involving lower esophagus was excised. Histopathology pointed towards inflammatory myofibroblastic tumor or inflammatory pseudotumor. Proliferation of myofibroblastic cells is more in IMT. In IPT it is more of an inflammatory reactive or regenerative entity and has an overlapping with immunoglobulin G4-related disease. Lesion often mimics malignancy.

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