scholarly journals Inhibition of γ-Radiation Induced DNA Damage in Plasmid pBR322 by TMG, a Water-soluble Derivative of Vitamin E

2002 ◽  
Vol 43 (2) ◽  
pp. 153-153 ◽  
Author(s):  
REMA RAJAGOPALAN ◽  
KHALIDA WANI ◽  
NAGARAJ G. HUILGOL ◽  
TSUTOMU V. KAGIYA ◽  
CHERUPALLY K. KRISHNAN NAIR
Keyword(s):  
Dna Damage ◽  
Vitamin E ◽  
Water Soluble ◽  
Plasmid Pbr322 ◽  
Γ Radiation ◽  
Radiation Induced

scholarly journals Krüppel-like factor 4 exhibits antiapoptotic activity following γ-radiation-induced DNA damage

Oncogene ◽  
2006 ◽  
Vol 26 (16) ◽  
pp. 2365-2373 ◽  
Author(s):  
A M Ghaleb ◽  
J P Katz ◽  
K H Kaestner ◽  
J X Du ◽  
V W Yang
Keyword(s):  
Dna Damage ◽  
Γ Radiation ◽  
Radiation Induced ◽  
Antiapoptotic Activity

Evaluation of γ-radiation-induced DNA damage in two species of bivalves and their relative sensitivity using comet assay

2014 ◽  
Vol 150 ◽  
pp. 1-8 ◽  
Author(s):  
M.K. Praveen Kumar ◽  
S.K. Shyama ◽  
B.S. Sonaye ◽  
U Roshini Naik ◽  
S.B. Kadam ◽  
...  
Keyword(s):  
Dna Damage ◽  
Comet Assay ◽  
Relative Sensitivity ◽  
Γ Radiation ◽  
Radiation Induced

Abundance of cyclin B1 regulates γ-radiation–induced apoptosis

Blood ◽  
2000 ◽  
Vol 95 (8) ◽  
pp. 2645-2650 ◽  
Author(s):  
Lisa A. Porter ◽  
Gurmit Singh ◽  
Jonathan M. Lee
Keyword(s):  
Cell Cycle ◽  
Dna Damage ◽  
Mammalian Cells ◽  
Hematopoietic Cells ◽  
Cyclin B1 ◽  
Regulatory Subunit ◽  
Potent Inducer ◽  
Γ Radiation ◽  
Radiation Induced ◽  
Induced Apoptosis

Abstract γ-Radiation is a potent inducer of apoptosis. There are multiple pathways regulating DNA damage-induced apoptosis, and we set out to identify novel mechanisms regulating γ-radiation–induced apoptosis in hematopoietic cells. In this report, we present data implicating the cyclin B1 protein as a regulator of apoptotic fate following DNA damage. Cyclin B1 is the regulatory subunit of the cdc2 serine/threonine kinase, and accumulation of cyclin B1 in late G2 phase of the cell cycle is a prerequisite for mitotic initiation in mammalian cells. We find that abundance of the cyclin B1 protein rapidly increases in several mouse and human hematopoietic cells (Ramos, DP16, HL60, thymocytes) undergoing γ-radiation–induced apoptosis. Cyclin B1 accumulation occurs in all phases of the cell cycle. Antisense inhibition of cyclin B1 accumulation decreases apoptosis, and ectopic cyclin B1 expression is sufficient to induce apoptosis. These observations are consistent with the idea that cyclin B1 is both necessary and sufficient for γ-radiation-induced apoptosis.

Inhibition of radiation-induced DNA damage in plasmid pBR322 by chlorophyllin and possible mechanism(s) of action

1999 ◽  
Vol 425 (1) ◽  
pp. 71-79 ◽  
Author(s):  
S.Santosh Kumar ◽  
R.C. Chaubey ◽  
T.P.A. Devasagayam ◽  
K.I. Priyadarsini ◽  
P.S. Chauhan
Keyword(s):  
Dna Damage ◽  
Plasmid Pbr322 ◽  
Radiation Induced

In vitro DNA damage characterisation studies on plasmid pBR322 after exposure to γ radiation by 60Co

2011 ◽  
Vol 291 (3) ◽  
pp. 661-664 ◽  
Author(s):  
Vedansha Jaiswal ◽  
Pragati Misra ◽  
P. K. Shukla ◽  
P. W. Ramteke ◽  
A. B. Tiku
Keyword(s):  
Dna Damage ◽  
Plasmid Pbr322 ◽  
Γ Radiation

Influence of ferulic acid on γ-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes

Toxicology ◽  
2006 ◽  
Vol 228 (2-3) ◽  
pp. 249-258 ◽  
Author(s):  
M. Srinivasan ◽  
A. Ram Sudheer ◽  
K. Raveendran Pillai ◽  
P. Raghu Kumar ◽  
P.R. Sudhakaran ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Dna Damage ◽  
Ferulic Acid ◽  
Primary Culture ◽  
Antioxidant Status ◽  
Rat Hepatocytes ◽  
Isolated Rat Hepatocytes ◽  
Γ Radiation ◽  
Radiation Induced ◽  
Isolated Rat

Caffeine does not potentiate γ-radiation induced DNA damage in ataxia telangiectasia lymphoblastoid cells

1998 ◽  
Vol 401 (1-2) ◽  
pp. 27-32 ◽  
Author(s):  
D.Gwyn Bebb ◽  
Patricia P. Steele ◽  
Pamela J. Warrington ◽  
Joyce A. Moffat ◽  
Barry W. Glickman
Keyword(s):  
Dna Damage ◽  
Ataxia Telangiectasia ◽  
Lymphoblastoid Cells ◽  
Γ Radiation ◽  
Radiation Induced

Ferulic acid (FA) abrogates γ-radiation induced oxidative stress and DNA damage by up-regulating nuclear translocation of Nrf2 and activation of NHEJ pathway

2017 ◽  
Vol 51 (1) ◽  
pp. 47-63 ◽  
Author(s):  
Ujjal Das ◽  
Krishnendu Manna ◽  
Amitava Khan ◽  
Mahuya Sinha ◽  
Sushobhan Biswas ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Ferulic Acid ◽  
Nuclear Translocation ◽  
Γ Radiation ◽  
Nhej Pathway ◽  
Radiation Induced
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