scholarly journals Apolipoprotein B mRNA Editing in the Liver and Small Intestine of Rats Fed on Beet Fiber, Soy Protein, and Fish Oil

1999 ◽  
Vol 63 (7) ◽  
pp. 1315-1317
Author(s):  
Reiko MIYAKAWA ◽  
Kei SONOYAMA ◽  
Takanori KASAI

2002 ◽  
Vol 278 (9) ◽  
pp. 7600-7606 ◽  
Author(s):  
Amy P. Patterson ◽  
Zhigang Chen ◽  
Deborah C. Rubin ◽  
Virginie Moucadel ◽  
Juan Lucio Iovanna ◽  
...  


1995 ◽  
Vol 36 (8) ◽  
pp. 1664-1675
Author(s):  
F. Giannoni ◽  
S.C. Chou ◽  
S.F. Skarosi ◽  
M.S. Verp ◽  
F.J. Field ◽  
...  


1999 ◽  
Vol 341 (3) ◽  
pp. 639-645 ◽  
Author(s):  
Mark P. SOWDEN ◽  
Heidi L. COLLINS ◽  
Harold C. SMITH ◽  
Timothy A. GARROW ◽  
Janet D. SPARKS ◽  
...  

The cDNA encoding rat betaine-homocysteine S-methyltransferase (BHMT) was isolated through production of monoclonal antibodies against protein fractions enriched with apolipoprotein B (apo B)-mRNA-editing complexes. BHMT mRNA was expressed predominantly in liver, and also in kidney, but not in small intestine. In stable McArdle RH-7777 (McA) cell lines expressing differing levels of BHMT, the editing efficiency of apo B mRNA was unchanged. Evaluation of apo B-mRNA expression revealed that steady-state levels were increased significantly and in parallel with BHMT protein expression. The highest levels of BHMT mRNA and BHMT enzyme activity expressed in stably transfected McA cells were comparable with those found in rat hepatocytes. In contrast to the changes in apo B-mRNA abundance, levels of other apolipoprotein-encoding mRNAs and several liver-specific and ubiquitously expressed mRNAs were unchanged by BHMT expression. In the cell line expressing the highest level of BHMT, apo B-containing lipoprotein secretion was increased, indicating utilization of increased endogenous message. Results suggest that apo B-mRNA abundance in McA cells is related to the expression of BHMT, an enzyme important in homocysteine metabolism.



1999 ◽  
Vol 40 (4) ◽  
pp. 623-635 ◽  
Author(s):  
Ba-Bie Teng ◽  
Scott Ochsner ◽  
Qian Zhang ◽  
Kizhake V. Soman ◽  
Paul P. Lau ◽  
...  


1990 ◽  
Vol 265 (36) ◽  
pp. 22446-22452 ◽  
Author(s):  
K Boström ◽  
Z Garcia ◽  
K S Poksay ◽  
D F Johnson ◽  
A J Lusis ◽  
...  




Author(s):  
Luciana Di Giorgio ◽  
Pablo Rodrigo Salgado ◽  
Adriana Noemi Mauri




2018 ◽  
pp. 297-317
Author(s):  
Nicholas O. Davidson


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