Dental Caries and Salivary Interleukin - 6 among Preterm Postpartum Women in Relation to Baby Birth Weight : Comparative Study

The study aimed to assess the number, localization and distribution of interleukin 6 (IL-6) positive cells in healthy pulp, acute and chronic pulpitis. The study group included 48 patients aged between 18-72, treated in University of Medicine and Pharmacy Grigore T. Popa Iasi, Romania. The pulpectomy was performed on 42 patients diagnosed with acute and chronic pulpitis. The other 6 patients, without signs of dental caries or periodontal disease, were submitted to extractions of teeth for orthodontic purposes, with pulpectomy performed before extraction. The pulp samples were examined with optic microscope. The detection and assessment of IL-6 were performed using immunohistochemical technique. Data were statistically analysed using non-parametric tests. According to morphopathological criteria, 42.85% were classified as acute pulpitis and 57.14% as chronic pulpitis. The pulp samples in control group were not associated with IL-6 positive cells. The analysis of all samples with acute and chronic pulpitis identified 73.80% samples with IL-6 and 26.20% associated with the absence of IL-6. The highest frequency of IL-6 positive cells was recorded in rich-cell zone of crown dental pulp. The systemic distribution of IL-6 positive cells was mostly diffused without well-defined orientation. IL-6 release in acute and chronic pulpitis is significantly higher comparing with healthy pulp tissue.

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Comparative study of anti-VEGF Ranibizumab and Interleukin-6 receptor antagonist Tocilizumab in Adjuvant-induced Arthritis

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2018.07.014 ◽

2018 ◽

Vol 356 ◽

pp. 65-75 ◽

Cited By ~ 6

Author(s):

Amany El-Shahawy Abdel-Maged ◽

Amany M. Gad ◽

Amal Kamal Abdel-Aziz ◽

Mohammad M. Aboulwafa ◽

Samar S. Azab

Keyword(s):

Comparative Study ◽

Receptor Antagonist ◽

Interleukin 6 ◽

Adjuvant Induced Arthritis ◽

Anti Vegf ◽

Interleukin 6 Receptor

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Prevalence of dental caries in adult south Indian population in association with dietary pattern: A comparative study

Journal of Pharmacy And Bioallied Sciences ◽

10.4103/jpbs.jpbs_155_20 ◽

2020 ◽

Vol 12 (5) ◽

pp. 546

Author(s):

Druvan Kavitha ◽

Anju Varghese ◽

Singh Prabath ◽

Rayar Sreeram ◽

Joseph Asha ◽

...

Keyword(s):

Dental Caries ◽

Comparative Study ◽

Dietary Pattern ◽

Indian Population ◽

South Indian Population ◽

South Indian

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Risks of Selected Fetal Adverse Pregnancy Outcomes at Advance Maternal Age

10.53350/pjmhs211582468 ◽

2021 ◽

Vol 15 (8) ◽

pp. 2468-2471

Author(s):

Saadia Yasmeen ◽

Sumayya . ◽

Javeria Saleem ◽

Jawairiah Liaqat ◽

Nadia Pervaiz ◽

...

Keyword(s):

Birth Weight ◽

Preterm Birth ◽

Low Birth Weight ◽

Pregnancy Outcomes ◽

Maternal Age ◽

Advanced Maternal Age ◽

Adverse Pregnancy Outcomes ◽

Control Group ◽

Postpartum Women ◽

Adverse Pregnancy

Background and Aim: Advanced maternal age pregnancy could be referred to as pregnancy after 35 years or older. The prevalence of postponing pregnancies is increasing day by day worldwide. However, limited evidence was found on advanced maternal age pregnancy association with fetal adverse outcomes. The present study aimed to evaluate the frequency of advanced maternal age selected fetal adverse pregnancy outcomes. Place and Duration: Obstetrics & Gynaecology department of Alkhidmat Hospital Kohat and Qazi Hussain Ahmad Medical Complex, Nowshera for duration of six months from November 2020 to April 2021. Materials and Methods: This single-centered retrospective study was conducted on 220 postpartum women in the study group (≥35 years) and 170 control group postpartum women (20-34 years) who delivered at Obstetrics & Gynaecology department of Alkhidmat Hospital Kohat and Qazi Hussain Ahmad Medical Complex, Nowshera after 28 gestational weeks. Individuals who met the inclusion criteria were enrolled and sampled based on randomized control sampling technique for both control and study groups. Data extraction checklist and pretested questionnaire were used for data collection from the maternal charts. Adverse pregnancy outcome and advanced maternal age was correlated adjusted relative risks and strength with a 95% confidence interval. SPSS version 20 was used for data analysis and considered p-value >0.05 as a statistical standard. Results: The adverse neonatal outcomes include low birth weight, preterm birth, and stillbirth with a prevalence 38 (17.4%), 46 (20.8%), and 31 (14.2%) respectively in the study group. In the control group, the incidence of low birth weight, preterm birth, and stillbirth was 21 (12.6%), 15 (14.6%) and 6 (3.5%) respectively. The stillbirth (ARR=3.16 95% CI (1.29–6.03) and preterm deliveries (ARR=2.71 95% CI (1.79–3.86) risk had significantly higher prevalence compared to control group advanced age pregnancy. Insignificance association was found between low birth weight and advanced maternal age. Conclusion: Stillbirth and preterm birth was the adverse fetal outcome significantly related with advanced maternal age pregnancy. There was no significant association between low birth weight and advanced maternal age. Keywords: Maternal age, Fetal Adverse Pregnancy Outcomes

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Demographic Profile, Mode of Delivery and Birth Weight in Teenage Pregnancy: A Prospective Comparative Study

Indian Journal of Obstetrics and Gynecology ◽

10.21088/ijog.2321.1636.6318.5 ◽

2018 ◽

Vol 6 (3) ◽

pp. 231-236

Author(s):

C.P. Jishabai ◽

◽

Sheela Gopalakrishnan ◽

Keyword(s):

Birth Weight ◽

Comparative Study ◽

Teenage Pregnancy ◽

Mode Of Delivery ◽

Demographic Profile ◽

Prospective Comparative Study

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Population-Based Estimation of Dental Caries and Periodontal Disease Rates of Gravid and Recently Postpartum Women in Lilongwe, Malawi

American Journal of Perinatology Reports ◽

10.1055/s-0039-1695003 ◽

2019 ◽

Vol 09 (03) ◽

pp. e268-e274

Author(s):

Kathleen M. Antony ◽

Peter N. Kazembe ◽

Ryan M. Pace ◽

Judy Levison ◽

Jesse Mlotha-Namarika ◽

...

Keyword(s):

Dental Caries ◽

Periodontal Disease ◽

Health Workers ◽

Population Based ◽

Oral Health Status ◽

World Health ◽

Postpartum Women ◽

Dental Disease ◽

Dmf Index ◽

Health Organization

Objectives The objective of this study was to determine the rate of dental caries and periodontal disease among gravid and recently postpartum women at five delivery centers within and surrounding Lilongwe, Malawi. Study Design We partnered with obstetric specialists, community health workers, and dentists to perform dental history interviews and dental examinations during the study period from December 2012 to May 2014. Dental examinations were performed according to World Health Organization standards to assess periodontal and oral health status. Results Among the 387 gravid and recently postpartum women, the rate of dental caries was 69.3% and the rate of composite dental disease (caries and periodontal disease) was 76.7%. The majority (69.5%) of women examined had a decayed-missing-filled (DMF) index greater than or equal to one; the average DMF Index was 2.48. The majority of women had never seen a dentist (62.8%). However, most did perform oral hygiene, two or more times per day (90.2%); most women reported brushing with toothpaste (88.1%). Conclusion When assessing this population for dental caries and periodontal disease, the rate of dental disease was high. Therefore, this may be an ideal setting to test for impactful interventions aimed at reducing caries and periodontal disease.

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