Efficacy and Safety of Oral Low Dose Theophylline in Jordanian Patients with Stable Chronic Obstructive Pulmonary Disease Treated at King Hussein Medical Center

2016 ◽  
Vol 23 (1) ◽  
pp. 34-40
Author(s):  
Rakan M. Haddad ◽  
Sultan K. Alsureehein ◽  
Ghaith Abu Alsamen
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Low Dose ◽  
Medical Center ◽  
Chronic Obstructive ◽  
Efficacy And Safety ◽  
Obstructive Pulmonary Disease

scholarly journals Simultaneous Assessment of Airway Instability and Respiratory Dynamics with Low-Dose 4D-CT in Chronic Obstructive Pulmonary Disease: A Technical Note

Respiration ◽  
2014 ◽  
Vol 87 (4) ◽  
pp. 294-300 ◽  
Author(s):  
Mark O. Wielpütz ◽  
Ralf Eberhardt ◽  
Michael Puderbach ◽  
Oliver Weinheimer ◽  
Hans-Ulrich Kauczor ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Low Dose ◽  
Technical Note ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
4D Ct ◽  
Respiratory Dynamics ◽  
Simultaneous Assessment

The Effects of Oral Almitrine on Pattern of Breathing and Gas Exchange in Patients with Chronic Obstructive Pulmonary Disease

1984 ◽  
Vol 66 (4) ◽  
pp. 435-442 ◽  
Author(s):  
J. R. Stradling ◽  
C. G. Nicholl ◽  
D. Cover ◽  
E. E. Davies ◽  
J. M. B. Hughes ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Gas Exchange ◽  
Pulmonary Disease ◽  
Low Dose ◽  
Statistical Significance ◽  
Chronic Obstructive ◽  
Inspiratory Flow Rate ◽  
Obstructive Pulmonary Disease ◽  
Oxygen Breathing ◽  
Arterial Po2

1. Almitrine at a low dose of 100 mg orally significantly raises Pao2 and lowers Paco2 in patients with chronic obstructive pulmonary disease, compared with placebo, when they were breathing air or 28% oxygen. 2. The estimated ideal alveolar — arterial Po2 difference was less after almitrine compared with placebo, when patients were breathing either air or 28% oxygen. 3. After almitrine overall ventilation breathing air increased by 10% but this did not reach statistical significance. During 28% oxygen breathing almitrine hardly altered overall ventilation but the inspiratory duty cycle (Ti/Ttot.) decreased and mean inspiratory flow rate (VT/Ti) increased compared with placebo. These changes were significant on a paired t-test (P<0.05). 4. Changes in both volume and pattern of breathing may explain the improved gas exchange in the lung after almitrine.

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