scholarly journals Transcranial Direct Current Stimulation in the Treatment of Subacute Post-Stroke Thalamic Aphasia

Author(s):  
William Campanella ◽  
Riccardo Pedrini ◽  
Lucilla Vestito ◽  
Lucio Marinelli ◽  
Carlo Trompetto ◽  
...  

Background: Although many studies have demonstrated the effectiveness of transcranial direct current stimulation (tDCS) in improving speech recovery in post-stroke aphasia, as far as we know patients affected by thalamic aphasia have never been investigated. Patient and method: A 65-year-old man with severe non-fluent aphasia due to a left thalamic haemorrhagic stroke underwent intensive daily speech therapy combined with tDCS.  Results: The patient showed progressive improvement with almost complete recovery of his speech disorder, behavioural disinhibition and apathy.  Conclusions: Our findings suggest that tDCS with concurrent speech therapy can be useful in patients with subcortical stroke lesions.

2020 ◽  
Vol 19 (2) ◽  
Author(s):  
Mohamad Hashim N ◽  
Jamil NFF ◽  
Ahmad Roslan NF ◽  
Mohd Zohdi WN ◽  
SF Salim M ◽  
...  

Transcranial Direct Current Stimulation (tDCS) is an adjunct to behavioral speech therapy to enhance the recovery of post-stroke dysphasia. Administration of tDCS involves the application of low- amplitude electrical currents through surface electrodes, which are placed onto the scalp to influence the neuronal activity.TDCS montage and patients' clinical characteristics are the important factors in determining the outcome of the intervention.  We aim to describe the clinical characteristics, outcomes and local limitation factors of five post-stroke patients who received TDCS combined with behavioural therapy for dysphasia. All patients, except for Case #5 showed improvement at day 10 post-intervention in several speech and language domains. TDCS is a promising adjunctive intervention in enhancing neuroplasticity activity in a post-stroke brain. A further well design case-controlled study is warranted to prove its efficacy in our local population. Local factors and limitations that may influence the outcome should be considered. 


2016 ◽  
Vol 20 (2) ◽  
pp. 252-257 ◽  
Author(s):  
Vania L.C. Carvalho Lima ◽  
Luanda A. Collange Grecco ◽  
Valéria C. Marques ◽  
Felipe Fregni ◽  
Clara R. Brandão de Ávila

Neurocase ◽  
2011 ◽  
Vol 17 (4) ◽  
pp. 318-322 ◽  
Author(s):  
Viviane F. Bueno ◽  
Andre R. Brunoni ◽  
Paulo S. Boggio ◽  
Isabela M. Bensenor ◽  
Felipe Fregni

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Caroline Schnakers ◽  
Zhong Sheng Zheng ◽  
Henry Millan ◽  
Sharon Lee ◽  
Melissa Howard ◽  
...  

Background: There is growing evidence even amongst those with chronic aphasia that transcranial direct current stimulation (tDCS) combined with behavioral speech therapy could boost language. However, current findings do not allow making strong recommendations for using tDCS in order to improve language in post-stroke aphasia. The efficacy of tDCS therefore still needs to be established using double-blind controlled randomized trials in large samples. Intervention: In this ongoing double-blind randomized placebo controlled trial study, participants were randomly assigned either to the tDCS group or to the sham group. Both groups had five consecutive days of 20 minutes session, using a FDA approved tDCS device (soterixmedical.com). Behavioral and neuroimaging data were performed the week before/after tDCS/sham intervention and again 3 months following treatment. Participants: 42 post-stroke patients with chronic aphasia (32 males; age: 61±11y; 0.9-18years post-injury; 32 ischemic stroke; 19 non-fluent aphasia). Eighteen patients were in the tDCS group. Main Outcome Measures: The Western Aphasia Battery-Revised (WAB-R), Communication Outcomes after Stroke, patient and family report (COAST). MRI Diffusion Tensor Imaging data (64 dir) were also collected. Statistical Analyses: Anova with repeated measures was used on the behavioral outcome measures with aphasia severity, age and time since injury as covariates in SPSS. The average fractional anisotropy (FA) and mean diffusivity (MD) were extracted per ROI from each participant and timepoint. Main Results: a) Behavioral. Groups differed, pre/post intervention, on the WAB-R total score, for the Auditory-Verbal Comprehension and Repetition subscores; b) Neuroimaging. Change in Spontaneous Speech and Auditory Verbal Comprehension negatively correlated with change in mean MD and FA, respectively, in Superior Cerebellar Peduncle for tDCS, but not sham. Conclusion: Our preliminary findings show a higher improvement in language functions (for both receptive and expressive language skills) in response to treatment (vs. sham). Neuroplasticity was observed in superior cerebellar peduncle in response to tDCS mediated language improvement.


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