scholarly journals Morel-Lavallee Syndrome: A Rare Tumefactive Lesion

2020 ◽  
Author(s):  
Mohamed Labied ◽  
Siham Salam ◽  
Salma Jabri ◽  
Dalal Laoudiyi ◽  
Kamilia Chbani ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Lower Leg ◽  
Differential Diagnoses ◽  
Fibrous Capsule ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Imaging Characteristics ◽  
French Surgeon ◽  
Over Time

First described by the French surgeon Maurice Morel-Lavallee in 1853, Morel-Lavallee syndrome (MLS) is a serolymphatic effusion resulting from tangential injury to richly vascularized tissues. The imaging characteristics may be variable over time due to lesion progression and the eventual organization of a fibrous capsule. We report a case of extensive MLS in the lower leg of a 12-year-old child. We discuss the ultrasound and magnetic resonance imaging findings and describe the differential diagnoses.

scholarly journals Computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report

2020 ◽  
Vol 48 (8) ◽  
pp. 030006052092043
Author(s):  
Ya-qiong Cui ◽  
Li-li Wang ◽  
Gang Huang ◽  
Lian-ping Zhao
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Malignant Neoplasm ◽  
Radical Excision ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Radiographic Appearance ◽  
Imaging Characteristics ◽  
Nasal Chondromesenchymal Hamartoma

Nasal chondromesenchymal hamartoma (NCMH) is a rare destructive benign neoplasm that predominantly develops in infants and young children. The lesion is usually located in the nasal cavity, often in the adjacent paranasal sinuses and orbital region and especially in the ethmoid sinus. Because the imaging characteristics of NCMH often mimic the features of malignant tumors, it is clinically important to study the radiographic appearance of this disease. Therefore, we herein present the computed tomography and magnetic resonance imaging findings of NCMH occurring in a 7-year-old girl. The mass was resected via an endoscopic surgical approach and definitively diagnosed as NCMH based on histologic and immunohistochemical analysis. However, signs of tumor recurrence manifested 45 months after surgery. NCMH can be locally aggressive with an expansive and destructive radiographic appearance, which highly implies a malignant neoplasm. Hence, an accurate diagnosis is essential to avoid potentially harmful therapies, and detailed computed tomography or magnetic resonance imaging should be performed prior to surgery. Selective arterial embolization is also an important part of preoperative management because the degree of enhancement may not be adequate to determine the blood supply of the tumor. Moreover, complete radical excision cannot guarantee that the lesion will not recur.

scholarly journals Fat-Containing Lesions of the Liver: A Review of Differential Diagnoses

2020 ◽  
Vol 71 (1) ◽  
pp. 12-18
Author(s):  
Andrew D. Chung
Keyword(s):  
Magnetic Resonance Imaging ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Differential Diagnoses ◽  
Malignant Neoplasms ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Invaluable Tool

The presence of intralesional fat provides an invaluable tool for narrowing the differential diagnosis for both benign and malignant neoplasms of the abdomen and pelvis. The ability to characterize intralesional fat is further expanded by the ability of magnetic resonance imaging to detect small quantities (intravoxel) of fat. The differential diagnosis of fat-containing lesions arising in the liver is broader than that of many other solid organs. However, this differential can be further refined depending on the type of fat (macroscopic vs intravoxel) and with the use of ancillary imaging findings. Radiologists must be aware of benign and malignant mimickers of common lesions.

The chameleon of neuroinflammation: magnetic resonance imaging characteristics of natalizumab-associated progressive multifocal leukoencephalopathy

2013 ◽  
Vol 19 (14) ◽  
pp. 1826-1840 ◽  
Author(s):  
Mike P Wattjes ◽  
Nancy D Richert ◽  
Joep Killestein ◽  
Marlieke de Vos ◽  
Esther Sanchez ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Progressive Multifocal Leukoencephalopathy ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Comprehensive Overview ◽  
Imaging Characteristics ◽  
Demyelinating Lesions ◽  
Asymptomatic Stage

Natalizumab is a monoclonal antibody against α4-integrin approved for the treatment of multiple sclerosis (MS) due to a positive effect on clinical and magnetic resonance imaging (MRI) outcome measures. However, one relatively rare but serious side effect of this drug is a higher risk of developing progressive multifocal leukoencephalopathy (PML). Since the FDA approval, more than 300 natalizumab-associated PML cases have been documented among more than 100,000 treated MS patients. MRI is a crucial tool in the surveillance of patients treated with natalizumab in order to detect possible signs of PML in the asymptomatic stage. Although classical imaging characteristics of PML are well established, MRI findings in natalizumab-associated PML, particularly in early disease stages, show rather new and heterogeneous imaging findings including different patterns of inflammation with contrast enhancement. This review provides a comprehensive overview of the heterogeneous imaging findings in natalizumab-associated PML in the context of the underlying pathophysiology, histopathology, and the diagnostic procedure. We describe the MRI patterns of PML lesion evolution and complications including immune reconstitution inflammatory syndrome (IRIS). Finally, we present guidelines to differentiate MRI findings in PML from inflammatory demyelinating lesions, to facilitate the early diagnosis of PML in patients treated with natalizumab.

scholarly journals Alterations in magnetic resonance imaging characteristics of bioabsorbable magnesium screws over time in humans: a retrospective single center study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Lena Sonnow ◽  
Andreas Ziegler ◽  
Gesa H. Pöhler ◽  
Martin H. Kirschner ◽  
Maximilian Richter ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Proton Density ◽  
Artifact Reduction ◽  
Single Center ◽  
Resonance Imaging ◽  
Imaging Characteristics ◽  
Single Center Study ◽  
Over Time ◽  
Center Study

Abstract Objectives This study aimed to examine the alterations in magnetic resonance imaging (MRI) characteristics of bioabsorbable magnesium (Mg) screws over time in a single center study in humans. Methods Seventeen patients who underwent medial malleolar (MM) fracture or osteotomy fixation using bioabsorbable Mg screws and had at least one postoperative MRI were included in this retrospective study. Six of them had more than one MRI in the postoperative period and were subject of the artifact reduction measurements. 1.5T or 3T MRI scans were acquired in different periods in each patient. The size and extent of the artifact were assessed independently by two experienced radiologists both quantitatively (distance measurement) and qualitatively (Likert scale). Results In the quantitative measurements of the six follow-up patients the screw’s signal loss artifact extent significantly decreased over the time, regardless of the MRI field strength (p<0.001). The mean artifact reduction was 0.06 mm (95% confidence interval [CI]: 0.05–0.07) for proton density weighted [PDw] and 0.04 mm (95% CI: 0.03–0.05) for T1 weighted (T1w) sequences per week. The qualitative assessments similarly showed significant artifact reduction in all MRI sequences. Different imaging findings, like bone marrow edema (BME), liquid collections, and gas formation were reported. The overall inter-reader agreement was high (κ=0.88, p<0.001). Conclusions The time-dependent artifact reduction of Mg screws in postoperative controls might indicate the expected self-degradation of the Mg implants. In addition, different MRI findings were reported, which are characteristic of Mg implants. Further MRI studies are required to get a better understanding of Mg imaging properties.

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