scholarly journals International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Rabbit

2021 ◽  
Vol 34 (3_Suppl) ◽  
pp. 183S-292S
Author(s):  
Alys E Bradley ◽  
Lyn Miller Wancket ◽  
Matthias Rinke ◽  
Margarita M Gruebbel ◽  
Brett H. Saladino ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
International Harmonization

scholarly journals Acute Kidney Injury (AKI)—The Toxicologic Pathologist’s Constant Companion

2018 ◽  
Vol 46 (8) ◽  
pp. 918-919
Author(s):  
Torrie A. Crabbs
Keyword(s):  
Acute Kidney Injury ◽  
Diagnostic Criteria ◽  
Kidney Injury ◽  
Scientific Session ◽  
Renal Hemodynamics ◽  
Annual Symposium ◽  
Drug Induced ◽  
New Therapies ◽  
International Harmonization

This article provides a brief overview of the second scientific session of the 37th Annual Symposium of the Society of Toxicologic Pathology in Indianapolis, Indiana, on June 18, 2018. The session was entitled “Acute Kidney Injury (AKI): The Toxicologic Pathologist’s Constant Companion” and was co-chaired by Drs. Zaher Radi and Torrie Crabbs. The fundamentals of tubule and interstitial anatomy were covered by Dr. Kevin McDorman, followed by a review of International Harmonization of Nomenclature and Diagnostic Criteria, Standard for Exchange of Nonclinical Data, and Drug-Induced Kidney Injury terminology, which was presented by Dr. Torrie Crabbs. Dr. Bruce Molitoris gave a talk on renal hemodynamics, microcirculation, and ischemia. Advances and challenges on new therapies and clinical targets of AKI were presented by Dr. Brad Rovin, and the session ended with a review from Dr. Zaher Radi on immunopathology of AKI.

scholarly journals International Harmonization of Nomenclature and Diagnostic Criteria (INHAND)

2014 ◽  
Vol 43 (5) ◽  
pp. 730-732 ◽  
Author(s):  
C. M. Keenan ◽  
J. Baker ◽  
A. Bradley ◽  
D. G. Goodman ◽  
T. Harada ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
International Harmonization

scholarly journals International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Non-proliferative and Proliferative Lesions of the Non-human Primate (M. fascicularis)

2021 ◽  
Vol 34 (3_Suppl) ◽  
pp. 1S-182S
Author(s):  
Karyn Colman ◽  
Rachel N. Andrews ◽  
Hannah Atkins ◽  
Theresa Boulineau ◽  
Alys Bradley ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
International Harmonization ◽  
Human Primate

International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Dog

2021 ◽  
Vol 49 (1) ◽  
pp. 5-109
Author(s):  
Jochen Woicke ◽  
Muthafar M. Al-Haddawi ◽  
Jean-Guy Bienvenu ◽  
Jessica M. Caverly Rae ◽  
Franck J. Chanut ◽  
...  
Keyword(s):  
Great Britain ◽  
North America ◽  
Diagnostic Criteria ◽  
Laboratory Animals ◽  
The Internet ◽  
Common Language ◽  
International Harmonization ◽  
Research Organizations ◽  
The World ◽  
Safety Studies

The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions) Project ( www.toxpath.org/inhand.asp ) is a joint initiative of the societies of toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP), and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying lesions observed in most tissues and organs from the dog used in nonclinical safety studies. Some of the lesions are illustrated by color photomicrographs. The standardized nomenclature presented in this document is also available electronically on the internet ( http://www.goreni.org/ ). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous lesions, lesions induced by exposure to test materials, and relevant infectious and parasitic lesions. A widely accepted and utilized international harmonization of nomenclature for lesions in laboratory animals will provide a common language among regulatory and scientific research organizations in different countries and increase and enrich international exchanges of information among toxicologists and pathologists.

International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Minipig

2021 ◽  
Vol 49 (1) ◽  
pp. 110-228
Author(s):  
Mikala Skydsgaard ◽  
Zuhal Dincer ◽  
Wanda M. Haschek ◽  
Kris Helke ◽  
Binod Jacob ◽  
...  
Keyword(s):  
Great Britain ◽  
North America ◽  
Diagnostic Criteria ◽  
Laboratory Animals ◽  
The Internet ◽  
Common Language ◽  
International Harmonization ◽  
Research Organizations ◽  
The World ◽  
Safety Studies

The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions) Project ( www.toxpath.org/inhand.asp ) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP), and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying microscopic lesions observed in most tissues and organs from the minipig used in nonclinical safety studies. Some of the lesions are illustrated by color photomicrographs. The standardized nomenclature presented in this document is also available electronically on the internet ( http://www.goreni.org/ ). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous lesions as well as lesions induced by exposure to test materials. Relevant infectious and parasitic lesions are included as well. A widely accepted and utilized international harmonization of nomenclature for lesions in laboratory animals will provide a common language among regulatory and scientific research organizations in different countries and increase and enrich international exchanges of information among toxicologists and pathologists.

scholarly journals International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) progress to date and future plans

2015 ◽  
Vol 28 (1) ◽  
pp. 51-53 ◽  
Author(s):  
Charlotte M. Keenan ◽  
Julia F. Baker ◽  
Alys E. Bradley ◽  
Dawn G. Goodman ◽  
Takanori Harada ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
International Harmonization ◽  
Future Plans

An adrenocortical oncocytoma with unusual mitochondrial inclusions and cytoplasmic crystals

1994 ◽  
Vol 52 ◽  
pp. 250-251
Author(s):  
W.T. Gunning ◽  
G.D. Haselhuhn ◽  
E.R. Phillips ◽  
S.H. Selman
Keyword(s):  
Adrenal Gland ◽  
Salivary Glands ◽  
Mitotic Activity ◽  
Diagnostic Criteria ◽  
Vascular Invasion ◽  
Benign Neoplasm ◽  
Benign Tumors ◽  
Nuclear Morphology ◽  
Case Presentation ◽  
Microscopic Evidence

Within the last few years, adrenal cortical tumors with features concordant with the diagnostic criteria attributed to oncocytomas have been reported. To date, only nine reported cases exist in the literature. This report is the tenth case presentation of a presumptively benign neoplasm of the adrenal gland with a rare differentiation. Oncocytomas are well recognized benign tumors of the thyroid, parathyroid, and salivary glands and of the kidney. Other organs also give rise to these types of tumors, however with less frequency than the former sites. The characteristics generally used to classify a tumor as an oncocytoma include the following criteria: the tumor is 1) usually a solitary circumscribed mass with no gross nor microscopic evidence of metastasis (no tissue nor vascular invasion), 2) fairly bland in terms of mitotic activity and nuclear morphology, and 3) composed of large eosinophillic cells in which the cytoplasm is packed full of mitochondria (Figure 1).

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