Incidence and predictors of premalignant cervical lesions among women in Jos University teaching hospital, Plateau state, Nigeria

2016 ◽  
Vol 10 (3) ◽  
pp. 138-144
Author(s):  
Ajayi Abraham Dare ◽  
Grace Daniel ◽  
Ari Eunice Samuel ◽  
Winna Folashade ◽  
Jacob Onyawole Rachael
2019 ◽  
Vol 2 (4) ◽  
pp. 191-196
Author(s):  
ED Jatau ◽  
OB Toma ◽  
OJ Egesie ◽  
DO Damulak ◽  
Z Ayuba ◽  
...  

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.


2019 ◽  
Vol 2 (4) ◽  
pp. 191-196
Author(s):  
ED Jatau ◽  
OB Toma ◽  
OJ Egesie ◽  
DO Damulak ◽  
Z Ayuba ◽  
...  

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.


2019 ◽  
Vol 2 (4) ◽  
pp. 191-196
Author(s):  
ED Jatau ◽  
OB Toma ◽  
OJ Egesie ◽  
DO Damulak ◽  
Z Ayuba ◽  
...  

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.


2019 ◽  
Vol 2 (4) ◽  
pp. 191-196
Author(s):  
ED Jatau ◽  
OB Toma ◽  
OJ Egesie ◽  
DO Damulak ◽  
Z Ayuba ◽  
...  

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.


2019 ◽  
Vol 2 (4) ◽  
pp. 191-196
Author(s):  
ED Jatau ◽  
OB Toma ◽  
OJ Egesie ◽  
DO Damulak ◽  
Z Ayuba ◽  
...  

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.


Author(s):  
Oluwasiji O Olaitan

Central obesity poses more threat to human health than general obesity and stress increases its presentation. This study assessed prevalence of central obesity and stress, and their association with hypertension. Two hundred and eighty-three health workers in Jos Teaching Hospital, Plateau State, Nigeria were randomly selected. Socio-demographic characteristics and lifestyles (physical activity, alcohol intake, smoking and stress) were evaluated by semi-structured and International Stress Management Association Questionnaire. Central obesity was determined by waist circumference.


Author(s):  
M. Shehu ◽  
H. Shehu ◽  
T. O. Ubanyi

Neonatal jaundice is defined as the yellowish discoloration of the skin and sclera due to accumulation of unconjugated bilirubin. This is common in newborns and if not detected and treated early can lead to severe morbidity and mortality. Aim: The aim of the study was to analyze the knowledge, attitude and practices of mothers in Bingham University Teaching Hospital on Neonatal Jaundice. Method: This was a descriptive cross-sectional study which was carried out among mothers coming for ante and post-natal clinics in Bingham University Teaching Hospital from March to June 2019, using consecutive sampling of mothers that came for ante and post-natal services that consented to the study. The knowledge, attitude and practice of Neonatal Jaundice (NNJ) was assessed using a pretested questionnaire which was analyzed using SPSS version 22. Results: The results showed that 80% of mothers >40 years are able to define jaundice correctly compared to the 30% in mothers <26 years. Thirty-seven percent of mothers did not know any single cause of NNJ. Knowledge on NNJ was significantly associated with occupation, education and parity with fisher’s exact test of 0.045, 0.034 and 0.026 respectively.  Only 16% of the mothers knew that phototherapy is the major form of treatment for NNJ, most will expose their babies to sunlight. Some traditional beliefs about the cause of NNJ includes bad blood, bad breastmilk, change in weather and evil eye. Conclusion: There is need for more health education talks, campaigns and enlightenment of mothers on NNJ.


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