Emollients: treatment for dry skin disorders in older people

1999 ◽  
Vol 4 (6) ◽  
pp. 269-274 ◽  
Author(s):  
Moira Crawford
Keyword(s):  
Older People ◽  
Skin Disorders ◽  
Dry Skin

Dry skin disorders

2020 ◽  
pp. 403-416
Keyword(s):  
Clinical Sign ◽  
Underlying Mechanism ◽  
Skin Disorders ◽  
Dry Skin ◽  
Netherton Syndrome ◽  
Collodion Baby ◽  
Harlequin Ichthyosis ◽  
The Common ◽  
Scaly Skin ◽  
Recessive Ichthyosis

This chapter on dry skin disorders describes a range of mainly genetic dermatoses whose predominant feature is dry scaly skin. It excludes conditions such as eczema where dry skin is a secondary clinical sign. The underlying mechanism of dry scaly skin is briefly discussed and an algorithm points to possible diagnoses. The focus is on the genetic ichthyoses, defined as congenital, lifelong, generalized dry and scaly skin. The common ichthyoses are non-inflammatory (ichthyosis vulgaris and X-linked recessive ichthyosis) but there are several inflammatory ichthyoses, some associated with fragile skin (blistering) and several with multisystem complications, such as Netherton syndrome. Salient features of each are reviewed with illustrations of selected cases and management is outlined. Two important neonatal presentations, collodion baby and harlequin ichthyosis, are described.

scholarly journals The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin

2016 ◽  
Vol 29 (3) ◽  
pp. 135-147 ◽  
Author(s):  
Simon G. Danby ◽  
Kirsty Brown ◽  
Tim Higgs-Bayliss ◽  
John Chittock ◽  
Lujain Albenali ◽  
...  
Keyword(s):  
Older People ◽  
Skin Barrier ◽  
Structure And Function ◽  
Barrier Structure ◽  
Dry Skin ◽  
And Function

Management of Pruritus

2010 ◽  
Vol 3 (7) ◽  
pp. 384-387 ◽  
Author(s):  
Ferhat Uddin
Keyword(s):  
Atopic Dermatitis ◽  
Effective Treatment ◽  
Disease Process ◽  
Underlying Disease ◽  
Skin Disorders ◽  
Dry Skin ◽  
Lichen Simplex Chronicus ◽  
Complex Process ◽  
Underlying Disease Process

Pruritus, or itch, is a common sensation that causes a person to want to scratch. It is a complex process that commonly occurs with skin disorders such as xerotic eczema, atopic dermatitis and urticaria. It may also be related to an underlying disease process such as cholestasis or hyperthyroidism or simply be caused by dry skin, especially in the cold. Effective treatment of pruritus can prevent scratch-induced complications such as lichen simplex chronicus and impetigo. Therapy is often aimed at eliminating the underlying cause first, followed by the management of the itchy sensation.

scholarly journals Pharmacotherapy for Skin Disorders in Older People

2012 ◽  
Vol 42 (2) ◽  
pp. 150-154
Author(s):  
Sarah Shen ◽  
Robert I Kelly
Keyword(s):  
Older People ◽  
Skin Disorders

scholarly journals A real-world, non-interventional Indian study on clinical assessment of intense moisturizing formulation in dry skin disorders

2021 ◽  
Vol 7 (6) ◽  
pp. 848
Author(s):  
Dhiraj S. Dhoot ◽  
Namrata Mahadkar ◽  
Hanmant Barkate
Keyword(s):  
Atopic Dermatitis ◽  
Global Assessment ◽  
Severity Index ◽  
Physician Global Assessment ◽  
Skin Area ◽  
Skin Disorders ◽  
Dry Skin ◽  
Product Categories ◽  
Retrospective Data Analysis ◽  
Good Improvement

<p><strong>Introduction: </strong>Moisturizers account for the largest and important skin care product categories and are the backbone in the management of dry skin conditions associated with atopic dermatitis (AD), psoriasis and ichthyosis. </p><p><strong>Methods: </strong>A multicentre, retrospective data analysis was done at 145 dermatology clinics across India in patients who were prescribed MaxRich®. Patients with history of xerosis with an identifiable causes like atopic dermatitis, psoriasis and ichthyosis were included in study. Effectiveness data in terms of improvement in Dry Skin Area and Severity Index (DASI) Score compared to baseline and physician global assessment at the end of treatment for improvement in xerosis were captured.</p><p><strong>Results: </strong>There was significant reduction in mean DASI score as compared to baseline at week 2 &amp; 4 (p&lt;0.01). As compared to baseline, a significant decrease in DASI score was observed by 47.7% and 82.4% at the end of week 2 and 4 respectively. As per physician global assessment, 458 patients (83.4%) noticed very good improvement in xerosis at the end of 4 weeks whereas 82 patients (14.9%) recorded moderate improvement. Similar results were also obtained for patient global assessment where 478 patients (87%) recorded very good improvement; 67 patients (12.2%) and 6 patients (1.1%) recorded moderate and mild improvement respectively. There were no adverse events reported with MaxRich®.</p><p><strong>Conclusion: </strong>MaxRich®, an intense moisturizer was effective in improvement of DASI score associated with atopic dermatitis, psoriasis and ichthyosis and can be considered as an adjunct therapy in the management of these skin disorders for better results.</p>

Pruritus in older people

2013 ◽  
Vol 23 (1) ◽  
pp. 1-14 ◽  
Author(s):  
KS Chen ◽  
PD Yesudian
Keyword(s):  
Adverse Effects ◽  
Older People ◽  
Drug Reactions ◽  
Dry Skin ◽  
Common Cause ◽  
Wide Range ◽  
Immunological Changes ◽  
Topical Treatments ◽  
Cutaneous Drug Reactions ◽  
Systemic Agents

SummaryPruritus in older people is caused by a wide range of dermatological, systemic, neurological and psychogenic diseases. It can also be attributed to various cutaneous drug reactions. The dermatological, neurological and immunological changes associated with ageing predispose older people to pruritus of a wide range of aetiologies. The most common cause of pruritus in older people is xerosis, or dry skin. Regular use of emollients is the mainstay of treatment for pruritus of any cause, with general measures aiming to ensure optimal skin hydration and to prevent the itch–scratch cycle. Topical treatments are generally better tolerated for localized pruritus. Anti-histamines are the predominant agents to treat pruritus, but can be inadequate in many cases. Numerous other systemic agents have been demonstrated to alleviate pruritus depending on the cause, but may be limited by their adverse effects. This article reviews the current published literature on pruritus in older people, with a practical approach to its evaluation and management in non-specialist settings.

Changes in corneocyte element concentrations occur in skin inner stratum corneum

1990 ◽  
Vol 48 (2) ◽  
pp. 146-147
Author(s):  
R. R. Warner
Keyword(s):  
Stratum Corneum ◽  
Human Skin ◽  
Element Concentration ◽  
Skin Barrier ◽  
Barrier Properties ◽  
Brick Wall ◽  
Inorganic Elements ◽  
Dry Skin ◽  
Skin Biopsies ◽  
Intercellular Lipid

Keratinocytes undergo maturation during their transit through the viable layers of skin, and then abruptly transform into flattened, anuclear corneocytes that constitute the cellular component of the skin barrier, the stratum corneum (SC). The SC is generally considered to be homogeneous in its structure and barrier properties, and is often shown schematically as a featureless brick wall, the “bricks” being the corneocytes, the “mortar” being intercellular lipid. Previously we showed the outer SC was not homogeneous in its composition, but contained steep gradients of the physiological inorganic elements Na, K and Cl, likely originating from sweat salts. Here we show the innermost corneocytes in human skin are also heterogeneous in composition, undergoing systematic changes in intracellular element concentration during transit into the interior of the SC.Human skin biopsies were taken from the lower leg of individuals with both “good” and “dry” skin and plunge-frozen in a stirred, cooled isopentane/propane mixture.

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