Negative pressure wound therapy in the management of wounds

Negative pressure wound therapy, the controlled application of sub-atmospheric pressure to the wound surface, is becoming an increasingly popular treatment modality for the management of wounds in both human and veterinary medicine. It is proposed to exert a number of actions on the wound environment to promote healing. It is well recognised in the management of acute and chronic wounds and with skin grafting. It shows promise in cases of exposed orthopaedic implants and postoperatively on high-risk closed surgical incisions. Close monitoring following application is essential to ensure continued function. Importantly, it is typically well tolerated with minimal associated complications. However, significant complications are reported, if rarely, hence careful decision-making should be implemented to ensure appropriate use.

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Management of Acute and Chronic Wounds Using Negative Pressure Wound Therapy With Instillation and Dwell Time: A Retrospective

WOUNDS A Compendium of Clinical Research and Practice ◽

10.25270/wnds/081421.01 ◽

2021 ◽

Author(s):

Franco Bassetto ◽

Eleonora de Antoni ◽

Sandro Rizzato ◽

Carlotta Scarpa

Keyword(s):

Surface Area ◽

Negative Pressure ◽

Dwell Time ◽

Negative Pressure Wound Therapy ◽

Chronic Wounds ◽

University Hospital ◽

Wound Surface ◽

Wound Therapy ◽

Surgical Wounds ◽

Infected Wounds

Introduction: The presence of debris covering a wound surface significantly impedes progression toward closure. Negative pressure wound therapy with instillation and dwell time (NPWTi-d) of topical wound solutions is a versatile tool that can be applied to various wound types to promote wound healing. At the University Hospital of Padova in Padova, Italy, NPWTi-d has been incorporated into wound management plans that include debridement and antibiotic therapy, as necessary, for a diverse population of patients with open wounds, including acute, chronic, and infected wounds. Objective: A retrospective analysis of 100 patients (53 male, 47 female; age range, 22-95 years) who underwent NPWTi-d was performed, and key healing outcomes observed in subgroups differentiated by sex, wound etiology, initial wound size, and topical instillation solution were reported. Materials and methods: Wound types included vascular ulcers, surgical wounds, dehiscences, and trauma; anatomic location of the wounds varied. Negative pressure wound therapy with instillation (0.05% sodium hypochlorite, normal saline, or 0.25% acetic acid) was implemented with a dwell time of 3 minutes to 10 minutes, followed by a negative pressure cycle length of 2 hours to 3.5 hours at -75 mm Hg to -125 mm Hg. Dressings were changed approximately every 3 days. Results: After a median of 11 days (range, 1-35 days), the wound surface area significantly decreased (P <.0001), percentage of infected wounds declined from 72% to 46%, and wound closure was attained in 91% of cases. A significant reduction in wound surface area was detected in both sexes, small- and medium-sized wounds, vascular ulcers, surgical wounds, dehiscences, trauma wounds, and pressure ulcers (P <.05). This effect was detected in wounds regardless of topical instillation solution (P <.0001). Conclusions: This study showed that NPWTi-d is a valuable treatment option in a variety of circumstances and can help the clinician achieve a range of therapy goals based on individual patient needs.

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The effects and use of negative pressure wound therapy – a set of case reports

Perspectives in Surgery ◽

10.33699/pis.2020.99.4.183-188 ◽

2020 ◽

Vol 99 (4) ◽

pp. 183-188

Keyword(s):

Wound Healing ◽

High Risk ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Chronic Wounds ◽

Wide Spectrum ◽

Case Reports ◽

Modern Medicine ◽

Wound Therapy ◽

Basic Set

Modern medicine offers a wide spectrum of wound healing resources for acute or chronic wounds. Negative pressure wound therapy (NPWT) is a very effective method, allowing complicated defects and wounds to heal. The basic set is usually provided with various special accessories to facilitate the use and support safe application of NPWT to high-risk tissue. Selected case reports are presented herein to document the special use and combinations of materials in negative pressure wound therapy.

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Burdock leaf and B&W ointment: A natural and suitable alternative to negative pressure wound therapy and skin grafting in the treatment of traumatic crush injury post surgical debridement

Journal of Pediatric Surgery Case Reports ◽

10.1016/j.epsc.2020.101751 ◽

2021 ◽

Vol 65 ◽

pp. 101751

Author(s):

Erin Whiteford ◽

Shahab Abdessalam

Keyword(s):

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Skin Grafting ◽

Surgical Debridement ◽

Crush Injury ◽

Wound Therapy ◽

Suitable Alternative

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Cost-efficacy of skin grafting techniques using negative pressure wound therapy and tissue-engineered skin for burns

10.1063/5.0047187 ◽

2021 ◽

Author(s):

Muhammad Hanif Nadhif ◽

Muhammad Satrio Utomo ◽

Muhammad Farel Ferian ◽

Farhan H. Taufikulhakim ◽

Nadine H. P. Soerojo ◽

...

Keyword(s):

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Skin Grafting ◽

Wound Therapy ◽

Cost Efficacy

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Combination of Three Different Negative Pressure Wound Therapy Applications and Free Flap for Open Elbow Joint Injury With Extensive Burns

Journal of Burn Care & Research ◽

10.1093/jbcr/irab228 ◽

2021 ◽

Author(s):

Junya Oshima ◽

Kaoru Sasaki ◽

Yukiko Aihara ◽

Masahiro Sasaki ◽

Yoichiro Shibuya ◽

...

Keyword(s):

Free Flap ◽

Negative Pressure ◽

Elbow Joint ◽

Negative Pressure Wound Therapy ◽

Skin Grafting ◽

Perioperative Period ◽

Wound Therapy ◽

Joint Injury ◽

Left Limb ◽

Effective Option

Abstract Negative pressure wound therapy (NPWT) for treating burns has a variety of therapeutic applications. Here, we present a case of a 53-year-old woman with self-inflicted burn injuries in whom NPWT was applied for three different purposes. The injured sites were the anterior neck, bilateral arms from the wrists upwards to the chest, and back. The left arm was deeply injured, and the elbow joint cavity was opened during treatment. First, NPWT was used for bridge to skin grafting on the entire upper left limb. Second, NPWT was used as a bolster dressing for the autograft after skin grafting was performed on the left arm except the open part of the joint. Third, NPWT over flap was used on the subsequent flap surgical site to address prolonged exudate from the flap margin. The exudate resolved after about a week. Good results were obtained using NPWT during the perioperative period of free flap transplantation for extensive open elbow joint burns. The use of NPWT is an effective option in the treatment of burns.

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