Should older hypertensive patients be kidney donors?

2019 ◽  
Vol 4 (6) ◽  
pp. 314-321
Author(s):  
Rhodri Pyart ◽  
Vinod S Dibbur ◽  
Maike Eylert ◽  
Ann Marsden ◽  
Rhian Cooke ◽  
...  
Keyword(s):  
Older Patients ◽  
Kidney Donor ◽  
Single Centre ◽  
Living Kidney Donor ◽  
Donor Pool ◽  
Hypertensive Patients ◽  
Additional Group ◽  
Single Centre Study ◽  
Donor Criteria ◽  
Marginal Donors

Relaxing living kidney donor criteria allows donor pool expansion, but the risks to marginal donors who are both older and hypertensive are not well defined. This single-centre study of donors compared post-nephrectomy changes in blood pressure and estimated kidney function stratified by age, gender and the presence of hypertension. Data from an additional group of hypertensive older patients undergoing unilateral nephrectomy for malignancy were also analysed.

scholarly journals SAT-096 LIVING KIDNEY DONOR CONVERSION RATES – A SINGLE CENTRE STUDY

2019 ◽  
Vol 4 (7) ◽  
pp. S46
Author(s):  
A. Jackson ◽  
J.A. Lee ◽  
C. Coomarasamy ◽  
H. Talreja
Keyword(s):  
Kidney Donor ◽  
Single Centre ◽  
Living Kidney Donor ◽  
Centre Study ◽  
Conversion Rates ◽  
Single Centre Study

scholarly journals SP776IMPACT OF PRE-TRANSPLANT HISTOLOGICAL SCORE ON FIVE YEARS GRAFT OUTCOMES OF KIDNEYS FROM MARGINAL DONORS: A SINGLE-CENTRE STUDY

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii634-iii634
Author(s):  
Paolo Carta ◽  
Leonardo Caroti ◽  
Elisa Buti ◽  
Giulia Antognoli ◽  
Egrina Dervishi ◽  
...  
Keyword(s):  
Single Centre ◽  
Centre Study ◽  
Histological Score ◽  
Single Centre Study ◽  
Marginal Donors

Four years' experience of live kidney donor follow-up: a single-centre study

2016 ◽  
Vol 1 (3) ◽  
pp. 140-143
Author(s):  
Maha Mohamed ◽  
Alison Callaway ◽  
Caroline Wroe
Keyword(s):  
Kidney Donor ◽  
Single Centre ◽  
Centre Study ◽  
Live Kidney Donor ◽  
Single Centre Study

scholarly journals Impact of the pre-transplant histological score on 3-year graft outcomes of kidneys from marginal donors: a single-centre study

2013 ◽  
Vol 28 (10) ◽  
pp. 2637-2644 ◽  
Author(s):  
P. Carta ◽  
M. Zanazzi ◽  
L. Caroti ◽  
E. Buti ◽  
A. Mjeshtri ◽  
...  
Keyword(s):  
Single Centre ◽  
Centre Study ◽  
Histological Score ◽  
Single Centre Study ◽  
Marginal Donors

scholarly journals Sort and Sieve: Pre-Triage Screening of Patients with Suspected COVID-19 in the Emergency Department

2021 ◽  
Vol 18 (17) ◽  
pp. 9271
Author(s):  
Kirsten R.C. Hensgens ◽  
Inge H.T. van Rensen ◽  
Anita W. Lekx ◽  
Frits H.M. van Osch ◽  
Lieve H.H. Knarren ◽  
...  
Keyword(s):  
Emergency Department ◽  
Older Patients ◽  
Primary Outcome ◽  
Screening Method ◽  
Single Centre ◽  
Medical Unit ◽  
Acute Medical Unit ◽  
Single Centre Study ◽  
Screening Accuracy ◽  
Specific Symptoms

Introduction. To reduce the risk of nosocomial transmission, suspected COVID-19 patients entering the Emergency Department (ED) were assigned to a high-risk (ED) or low-risk (acute medical unit, AMU) area based on symptoms, travel and contact history. The objective of this study was to evaluate the performance of our pre-triage screening method and to analyse the characteristics of initially undetected COVID-19 patients. Methods. This was a retrospective, observational, single centre study. Patients ≥ 18 years visiting the AMU-ED between 17 March and 17 April 2020 were included. Primary outcome was the (correct) number of COVID-19 patients assigned to the AMU or ED. Results. In total, 1287 patients visited the AMU-ED: 525 (40.8%) AMU, 762 (59.2%) ED. Within the ED group, 304 (64.3%) of 473 tested patients were COVID-19 positive, compared to 13 (46.4%) of 28 tested patients in the AMU group. Our pre-triage screening accuracy was 63.7%. Of the 13 COVID-19 patients who were initially assigned to the AMU, all patients were ≥65 years of age and the majority presented with gastro-intestinal or non-specific symptoms. Conclusion. Older COVID-19 patients presenting with non-specific symptoms were more likely to remain undetected. ED screening protocols should therefore also include non-specific symptoms, particularly in older patients.

scholarly journals Microtransplantation Improves the Outcome of Older Patients With Newly Diagnosed Acute Myeloid Leukaemia: a Single-centre Study With Long-term Follow-up

2022 ◽  
Author(s):  
Juan Liu ◽  
Xiao-mei Huang ◽  
Si-yuan Zhao ◽  
Ya-kun Yang ◽  
Yuan-yuan Qu ◽  
...  
Keyword(s):  
Overall Survival ◽  
Stem Cell ◽  
Complete Remission ◽  
Older Patients ◽  
Newly Diagnosed ◽  
Single Centre ◽  
Free Survival ◽  
Single Centre Study ◽  
Acute Myeloid

Abstract Purpose: This retrospective single-centre study was to validate the efficacy and safety of microtransplantation (or micro-stem cell transplantation, MST) in the treatment of older patients with acute myeloid leukemia (AML).Methods: MST combines chemotherapy and human leukocyte antigen (HLA)-mismatched peripheral blood stem cell infusion without graft-versus-host disease (GVHD) prophylaxis. In total, 26 newly diagnosed AML patients were enrolled in our study from April 2008 to April 2018. The deadline date of follow-up was December 31, 2019. All of them received MST. Patients were divided into 2 age groups: 60~70 years (n=17) and >70 years (n=9). The outcomes of complete remission (CR) rate, overall survival (OS), leukemia free survival (LFS), hematopoietic recovery time, and treatment related toxicities were analyzed and summarized in this study.Results: 10 patients were still alive with complete remission (CR) at the deadline date, and the median overall survival (OS) was 64 months (range, 21-135 months). The CR, relapse and nonrelapse mortality rates were 84.6%, 38.5% and 30%, respectively. Both OS (p < 0.0001) and leukaemia free survival (LFS) (p < 0.0001) were significantly higher in the younger group than in the older group. The median times of neutrophil and platelet recovery were 12 days and 14 days, respectively. Conclusions: These data showed that MST could be an alternative treatment for older AML patients.

Opting out: a single-centre pilot study assessing the reasons for and the psychosocial impact of withdrawing from living kidney donor evaluation

2017 ◽  
Vol 43 (11) ◽  
pp. 756-761 ◽  
Author(s):  
Carrie Thiessen ◽  
Zainab Jaji ◽  
Michael Joyce ◽  
Paula Zimbrean ◽  
Peter Reese ◽  
...  
Keyword(s):  
Pilot Study ◽  
Psychosocial Impact ◽  
Kidney Donor ◽  
Single Centre ◽  
Living Kidney Donor ◽  
Opting Out ◽  
Donor Evaluation
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