Vector-borne disease distributions and risks to the UK

2020 ◽  
Vol 11 (5) ◽  
pp. 210-217
Author(s):  
Donato Traversa

In the recent decades, the geographic distribution of vector-borne diseases (VBDs) of dogs and cats has changed for intrinsic and extrinsic reasons. Therefore some infections/infestations, some of zoonotic concern, have been recorded in geographic areas where they were unexpected. In Europe, arthropods (e.g. ticks, fleas, mosquitoes and sand flies) and the pathogens that they transmit are in general considered to be more frequent in the Mediterranean Basin. Nonetheless, a possible occurrence in other regions should not be a priori excluded, given that travels of animals (to or imported from endemic areas), movements of goods and global warming all may foster the introduction of vectors and/or transmitted pathogens in previously free areas. This could also be the case in the UK, which, because of its territorial characteristics as an island area in north-western Europe, is traditionally considered at minor risk of VBDs. Given the growing increase of movements and travels of pets, and changes in the phenology of many arthropod vectors, it is crucial that veterinary practitioners are aware of and prepared to diagnose, treat and control a series of unexpected diseases.

2020 ◽  
Vol 25 (3) ◽  
pp. 1-6
Author(s):  
Donato Traversa

In the recent decades, the geographic distribution of vector-borne diseases (VBDs) of dogs and cats has changed for intrinsic and extrinsic reasons. Therefore some infections/infestations, some of zoonotic concern, have been recorded in geographic areas where they were unexpected. In Europe, arthropods (e.g. ticks, fleas, mosquitoes and sand flies) and the pathogens that they transmit are in general considered to be more frequent in the Mediterranean Basin. Nonetheless, a possible occurrence in other regions should not be a priori excluded, given that travels of animals (to or imported from endemic areas), movements of goods and global warming all may foster the introduction of vectors and/or transmitted pathogens in previously free areas. This could also be the case in the UK, which, because of its territorial characteristics as an island area in north-western Europe, is traditionally considered at minor risk of VBDs. Given the growing increase of movements and travels of pets, and changes in the phenology of many arthropod vectors, it is crucial that veterinary practitioners are aware of and prepared to diagnose, treat and control a series of unexpected diseases.


2009 ◽  
Vol 9 (1) ◽  
pp. 1521-1560 ◽  
Author(s):  
M. Beekmann ◽  
R. Vautard

Abstract. The variability of the relative sensitivity to volatile organic compounds (VOC) or NOx emissions, the chemical regime, over Europe during summers 2001 to 2003 is simulated with a regional scale transport-chemistry model. The robustness of chemical regimes is shown. A VOC sensitive regime over North-Western Europe and a mainly NOx sensitive regime over the Mediterranean basin and Eastern Europe are found, confirming earlier published results. The chemical regime time variability, its robustness to several environmental factors (seasonality, interannual variability) and to model uncertainty are thoroughly analysed. The chemical regime spatial structure only slightly depends on the ozone target considered (daily ozone maximum or AOT40, SOMO35, ...). Differences between particular years and summer months are weak. Day to day variability is significant but does not change the occurrence of one or another chemical regime over North-Western Europe and the Mediterranean basin. Expected decreases in anthropogenic NOx emissions over Europe since the last and for the next few decades have shifted and will shift chemical regimes to more NOx sensitive. The predictive and explanatory use of chemical regime indicator species is also investigated. For all cases but near ship tracks over the Mediterranean basin, the spatial pattern of chemical regimes appears to be robust with respect to model uncertainty.


2010 ◽  
Vol 10 (20) ◽  
pp. 10067-10084 ◽  
Author(s):  
M. Beekmann ◽  
R. Vautard

Abstract. The variability of the relative sensitivity of photochemical ozone formation to volatile organic compounds (VOC) and NOx emissions, the chemical regime, over Europe during summers 2001 to 2003 is simulated with a regional scale transport-chemistry model. The robustness and variability of chemical regimes is shown. A VOC sensitive regime over North-Western Europe and a mainly NOx sensitive regime over the Mediterranean basin and Eastern Europe are found, confirming earlier published results. The chemical regime time variability, its robustness with respect to several environmental factors (seasonality, interannual variability) and with respect to model uncertainty are thoroughly analysed. For the regions with well pronounced chemical regimes over North-Western Europe and the Mediterranean, the chemical regime occurrence only slightly depends on the ozone target considered – daily ozone or Ox (= O3 + NO2) maximum or mean, AOT's, SOMO35, .... For these regions, differences between particular years and summer months are weak, day to day variability is significant but does not change the occurrence of one or another chemical regime. On the contrary, over North-Eastern Germany, the chemical regime changes form one day to another and is also dependent on the ozone target chosen. Expected decreases in anthropogenic NOx emissions over Europe since the last and for the next few decades have shifted and will shift chemical regimes to more NOx sensitive. The predictive skill of chemical regime indicator species is made evident at continental scale, extending their spatial range of applicability with respect to earlier studies. Several sensitivity tests were performed in order to account for major sources of model uncertainty. With the exception of regions near ship tracks over the Mediterranean basin, the spatial pattern of chemical regimes appears to be robust with respect to model uncertainty for all cases tested.


Organization ◽  
2021 ◽  
pp. 135050842110209
Author(s):  
Martin Parker

In this review I consider the 20 years that have passed since the publication of my book Against Management. I begin by locating it in the context of the expanding business schools of the UK in the 1990s, and the growth of CMS in north western Europe. After positioning the book within its time, and noting that the book is now simultaneously highly cited and irrelevant, I then explore the arguments I made in the final chapter. If the book is of interest for the next two decades, it because it gestures towards the importance of alternative forms of organization, which I continue to maintain are not reducible to ‘management’. Given the intensifying crises of climate, ecology, inequality and democracy, developing alternatives must be understood as the historical task of CMS within the business school and I propose a ten-point manifesto in support of that commitment.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Ranju Ravindran Santhakumari Manoj ◽  
Maria Stefania Latrofa ◽  
Sara Epis ◽  
Domenico Otranto

Abstract Background Wolbachia is an obligate intracellular maternally transmitted, gram-negative bacterium which forms a spectrum of endosymbiotic relationships from parasitism to obligatory mutualism in a wide range of arthropods and onchocercid nematodes, respectively. In arthropods Wolbachia produces reproductive manipulations such as male killing, feminization, parthenogenesis and cytoplasmic incompatibility for its propagation and provides an additional fitness benefit for the host to protect against pathogens, whilst in onchocercid nematodes, apart from the mutual metabolic dependence, this bacterium is involved in moulting, embryogenesis, growth and survival of the host. Methods This review details the molecular data of Wolbachia and its effect on host biology, immunity, ecology and evolution, reproduction, endosymbiont-based treatment and control strategies exploited for filariasis. Relevant peer-reviewed scientic papers available in various authenticated scientific data bases were considered while writing the review. Conclusions The information presented provides an overview on Wolbachia biology and its use in the control and/or treatment of vectors, onchocercid nematodes and viral diseases of medical and veterinary importance. This offers the development of new approaches for the control of a variety of vector-borne diseases. Graphic Abstract


2022 ◽  
Vol 78 (02) ◽  
pp. 6619-2022
Author(s):  
WIESŁAW NIEDBALSKI

The article reviews the history of BT occurrence in Europe and its present status. It describes the distribution of BT in Europe before 1998, the emergence of BTV in southern and eastern Europe in 1998-2006 and the epidemiology of BT in north-western Europe after 2006. Up to 1998, sporadic cases of BT were noted in Cyprus, on the Iberian Peninsula and on several Greek islands. However, since 1998, probably due to climatic changes, BTV has spread northwards into the Mediterranean Basin, where five BTV serotypes (1, 2, 4, 9 and 16) have been identified. In August 2006, BTV passed for the first time latitude 50°N, and BT outbreaks caused by BTV serotype 8 occurred in the Netherlands, Belgium, Germany, France and Luxembourg. Mass vaccination campaigns implemented in Europe in the spring of 2008 quickly limited the spread of disease caused by BTV-8, and it was eradicated by 2011. However, after a 3-year break, in September 2015, BTV-8 re-emerged in Europe, in central France, and subsequently spread throughout the entire country. In the following years, BTV-8 outbreaks were found in Switzerland, Germany, Belgium and Spain. In addition to BTV-8 outbreaks, BTV serotypes 1, 2, 4, 9 and 16 have recently circulated in Europe. As revealed by phylogeographic inference, the recent spread of BTV in Europe is a consequence of climatic, landscape and vertebrate host factors


2017 ◽  
Vol 31 (1) ◽  
Author(s):  
Ann M. Powers

SUMMARYBeginning in 2004, chikungunya virus (CHIKV) went from an endemic pathogen limited to Africa and Asia that caused periodic outbreaks to a global pathogen. Given that outbreaks caused by CHIKV have continued and expanded, serious consideration must be given to identifying potential options for vaccines and therapeutics. Currently, there are no licensed products in this realm, and control relies completely on the use of personal protective measures and integrated vector control, which are only minimally effective. Therefore, it is prudent to urgently examine further possibilities for control. Vaccines have been shown to be highly effective against vector-borne diseases. However, as CHIKV is known to rapidly spread and generate high attack rates, therapeutics would also be highly valuable. Several candidates are currently being developed; this review describes the multiple options under consideration for future development and assesses their relative advantages and disadvantages.


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