Subjective Sleep Quality and Depressive Symptoms in Patients with the Chronic Fatigue Syndrome

2002 ◽  
Vol 10 (2) ◽  
pp. 19-28 ◽  
Author(s):  
A. W. Graffelman ◽  
A. Knuistingh Neven ◽  
L. Nagelkerken ◽  
H. Petri ◽  
M. P. Springer
2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Jessie S. M. Chan ◽  
Rainbow T. H. Ho ◽  
Ka-fai Chung ◽  
Chong-wen Wang ◽  
Tzy-jyun Yao ◽  
...  

Objectives. To evaluate the effectiveness of Baduanjin Qigong exercise on sleep, fatigue, anxiety, and depressive symptoms in chronic fatigue syndrome- (CFS-) like illness and to determine the dose-response relationship.Methods. One hundred fifty participants with CFS-like illness (mean age= 39.0,SD = 7.9) were randomly assigned to Qigong and waitlist. Sixteen 1.5-hour Qigong lessons were arranged over 9 consecutive weeks. Pittsburgh Sleep Quality Index (PSQI), Chalder Fatigue Scale (ChFS), and Hospital Anxiety and Depression Scale (HADS) were assessed at baseline, immediate posttreatment, and 3-month posttreatment. The amount of Qigong self-practice was assessed by self-report.Results. Repeated measures analyses of covariance showed a marginally nonsignificant (P= 0.064) group by time interaction in the PSQI total score, but it was significant for the “subjective sleep quality” and “sleep latency” items, favoring Qigong exercise. Improvement in “subjective sleep quality” was maintained at 3-month posttreatment. Significant group by time interaction was also detected for the ChFS and HADS anxiety and depression scores. The number of Qigong lessons attended and the amount of Qigong self-practice were significantly associated with sleep, fatigue, anxiety, and depressive symptom improvement.Conclusion. Baduanjin Qigong was an efficacious and acceptable treatment for sleep disturbance in CFS-like illness. This trial is registered with Hong Kong Clinical Trial Register:HKCTR-1380.


2008 ◽  
Vol 1 ◽  
pp. CMPsy.S704
Author(s):  
Stefan Begré ◽  
Tobias Lütgert ◽  
Luca Remonda ◽  
Roland Wiest ◽  
Claus Kiefer ◽  
...  

Chronic fatigue syndrome (CFS) is characterized by disabling fatigue of unknown etiology. The thalamus is a key subcortical structure in sleep disorders and certain cognitive functions previously shown to be impaired in CFS patients. We investigated the association between subjective sleep quality and thalamic size in CFS. Twelve right-handed CFS patients and 12 age-, gender-, and handedness-matched healthy controls completed the Jenkins Sleep Questionnaire in order to assess subjective sleep problems. Thalamic size was determined by MR-based volumetry. More sleep problems correlated with greater total thalamic volume in patients (rP = 0.62, 95% CI 0.07–0.88, p = 0.032) but not in controls (rP = −0.034, p = 0.30). In post hoc analysis, more sleep problems correlated with right thalamic size in patients (rP = 0.70, 95% CI 0.21–0.91, p = 0.012) but not in controls (rP = −0.080, p = 0.81). Our preliminary results provide a basis for further studies on a possible role of the thalamus in sleep complaints and fatigue of patients with CFS.


2017 ◽  
Vol 13 (09) ◽  
pp. 1057-1066 ◽  
Author(s):  
Elisha K. Josev ◽  
Melinda L. Jackson ◽  
Bei Bei ◽  
John Trinder ◽  
Adrienne Harvey ◽  
...  

2018 ◽  
Author(s):  
Charlotte Mary Horne ◽  
Ray Norbury

Increasing evidence suggests that eveningness is associated with increased risk for depression. Eveningness, however, is also associated with poor sleep quality and the unique role of eveningness in depressive symptomatology remains to be elucidated. The goal of the current study, therefore, was to examine the inter-relationships between eveningness, subjective sleep quality and depressive symptoms in healthy participants free of current or previous depression and sleep disorder. Here, 167 healthy participants (mean age 24.16, 129/38 females/males) completed the reduced Morningness-Eveningness Questionnaire (rMEQ), the Pittsburgh Sleep Quality Index (PSQI) and the Centre for Epidemiological Studies Depression Scale (CES-D). Bootstrap mediation analysis for a simple mediation model including rMEQ, PSQI and CES-D was applied. Eveningness was associated with increased depressive symptoms and mediation analysis showed that this relationship was partly mediated by sleep quality. Our results suggest that indicators of depression observed in evening-type individuals cannot be attributed exclusively to disturbed sleep. We suggest that interventions that target both sleep quality and dysfunctionl cognitive styles would be optimal to promote well-being in evening-type individuals.


2019 ◽  
Vol 24 (3) ◽  
pp. 580-592 ◽  
Author(s):  
Maria Elizabeth Loades ◽  
Katharine A. Rimes ◽  
Sheila Ali ◽  
Trudie Chalder

Introduction:Previous research has indicated that co-morbid depression is common in adolescents with chronic fatigue syndrome (CFS).Objectives:We sought to compare the characteristics of depressive symptoms in adolescents with CFS to those of healthy controls (HCs) and illness controls (adolescents with asthma).Design:Case-control study nested within a prospective clinical cohort.Methods:A total of 121 adolescents with CFS who attended an initial assessment at two specialist CFS units completed the Children’s Depression Inventory (CDI). Their responses were compared to 80 HCs and 27 adolescents with asthma (illness controls). The clinical cohort of adolescents with CFS completed questionnaires at assessment, and those who were seen subsequently for treatment at the CFS unit (68%) completed the measures again at their first treatment session.Results:CFS participants scored significantly higher on all the depression subscales than participants with asthma and HCs. Depression score explained 11% of the variance in subsequent fatigue, but only 1.9% of the variance in physical functioning. Depression score also explained most (68%) of the variance in subsequent depression.Conclusion:Depressive symptoms are more prominent in adolescents with CFS than in HCs or illness controls. These symptoms also appear to remain over time during a naturalistic follow-up where no treatment was provided. This highlights the need for further research into depression in CFS, including stratifying treatment outcomes by depression status to determine what is effective at addressing these symptoms.


1992 ◽  
Vol 26 (2) ◽  
pp. 249-256 ◽  
Author(s):  
Ian Hickie ◽  
Andrew Lloyd ◽  
Denis Wakefield

Associations between immunological and psychological dysfunction in 33 patients with Chronic Fatigue Syndrome (CFS) were examined before and in response to treatment in a double blind, placebo-controlled trial of high dose intravenous immunoglobulin. Only those patients who received active immunotherapy demonstrated a consistent pattern of correlations between improvement in depressive symptoms and markers of cell-mediated immunity (CMI). This finding lends some support to the hypothesis that depressive symptoms in patients with CFS occur secondary to, or share a common pathophysiology with, immunological dysfunction. This pattern and the lack of strong associations between depression and immunological disturbance prior to treatment are less supportive of the view that CFS is primarily a form of depressive disorder or that immunological dysfunction in patients with CFS is secondary to concurrent depression.


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