Qigong Exercise Alleviates Fatigue, Anxiety, and Depressive Symptoms, Improves Sleep Quality, and Shortens Sleep Latency in Persons with Chronic Fatigue Syndrome-Like Illness

Objectives. To evaluate the effectiveness of Baduanjin Qigong exercise on sleep, fatigue, anxiety, and depressive symptoms in chronic fatigue syndrome- (CFS-) like illness and to determine the dose-response relationship.Methods. One hundred fifty participants with CFS-like illness (mean age= 39.0,SD = 7.9) were randomly assigned to Qigong and waitlist. Sixteen 1.5-hour Qigong lessons were arranged over 9 consecutive weeks. Pittsburgh Sleep Quality Index (PSQI), Chalder Fatigue Scale (ChFS), and Hospital Anxiety and Depression Scale (HADS) were assessed at baseline, immediate posttreatment, and 3-month posttreatment. The amount of Qigong self-practice was assessed by self-report.Results. Repeated measures analyses of covariance showed a marginally nonsignificant (P= 0.064) group by time interaction in the PSQI total score, but it was significant for the “subjective sleep quality” and “sleep latency” items, favoring Qigong exercise. Improvement in “subjective sleep quality” was maintained at 3-month posttreatment. Significant group by time interaction was also detected for the ChFS and HADS anxiety and depression scores. The number of Qigong lessons attended and the amount of Qigong self-practice were significantly associated with sleep, fatigue, anxiety, and depressive symptom improvement.Conclusion. Baduanjin Qigong was an efficacious and acceptable treatment for sleep disturbance in CFS-like illness. This trial is registered with Hong Kong Clinical Trial Register:HKCTR-1380.

Download Full-text

Subjective Sleep Quality and Depressive Symptoms in Patients with the Chronic Fatigue Syndrome

Journal of Chronic Fatigue Syndrome ◽

10.1300/j092v10n02_03 ◽

2002 ◽

Vol 10 (2) ◽

pp. 19-28 ◽

Cited By ~ 3

Author(s):

A. W. Graffelman ◽

A. Knuistingh Neven ◽

L. Nagelkerken ◽

H. Petri ◽

M. P. Springer

Keyword(s):

Depressive Symptoms ◽

Chronic Fatigue Syndrome ◽

Sleep Quality ◽

Chronic Fatigue ◽

Subjective Sleep Quality ◽

Subjective Sleep ◽

Fatigue Syndrome

Download Full-text

Subjective sleep quality and association with depression syndrome, chronic diseases and health-related physical fitness in the middle-aged and elderly

10.21203/rs.2.23848/v4 ◽

2021 ◽

Author(s):

Min-Fang Hsu ◽

Kang-Yun Lee ◽

Tsung-Ching Lin ◽

Wen-Te Liu ◽

Shu-Chuan Ho

Keyword(s):

Depressive Symptoms ◽

Physical Fitness ◽

Sleep Quality ◽

Chronic Diseases ◽

Sleep Latency ◽

Middle Aged ◽

Subjective Sleep Quality ◽

Subjective Sleep ◽

Self Rated Health ◽

Health Related

Abstract Background: As a complex phenomenon, sleep quality is difficult to objectively define and measure, and multiple factors related to sleep quality, such as age, lifestyle, physical activity, and physical fitness, feature prominently in older adult populations. The aim of the present study was to evaluate subjective sleep quality using the Pittsburgh Sleep Quality Index (PSQI) and to associate sleep quality with health-related physical fitness factors, depressive symptoms, and the number of chronic diseases in the middle-aged and elderly.Methods: We enrolled a total of 283 middle-aged and elderly participants from a rehabilitation clinic or health examination department. The PSQI was used to evaluate sleep quality. The health-related fitness assessment included anthropometric and physical fitness parameters. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale (CES-D) short form. Data were analyzed with SPSS 18.0, and descriptive statistics and logistic regression analysis were used for the analyses.Results: Overall, 27.9% of participants in this study demonstrated bad sleepers (with a PSQI score of >5), 10.2% of study participants frequently used sleep medication to help them fall asleep, and 6.0% reported having significant depressive symptoms (with a CES-D score of ≥10). There are two major findings: (1) depression symptoms, the number of chronic diseases, self-rated health, and arthritis were significantly associated with a poor sleep quality, and (2) the 2-min step test was associated with longer sleep latency. These results confirmed that the 2-min step was associated with a longer sleep latency among the health-related physical fitness items.Conclusions: Our study found that depressive syndrome, chronic disease numbers, a poor self-rated health status, and arthritis were the main risk factors that influenced subjective sleep quality.

Download Full-text

Systematic Review of Sleep Characteristics in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Healthcare ◽

10.3390/healthcare9050568 ◽

2021 ◽

Vol 9 (5) ◽

pp. 568

Author(s):

Rebekah Maksoud ◽

Natalie Eaton-Fitch ◽

Michael Matula ◽

Hélène Cabanas ◽

Donald Staines ◽

...

Keyword(s):

Systematic Review ◽

Chronic Fatigue Syndrome ◽

Sleep Quality ◽

Sleep Latency ◽

Chronic Fatigue ◽

Myalgic Encephalomyelitis ◽

Objective Measures ◽

Fatigue Syndrome ◽

Multiple Sleep Latency ◽

Multiple Sleep Latency Testing

(1) Background—Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multifaceted illness characterized by profound and persistent fatigue unrelieved by rest along with a range of other debilitating symptoms. Experiences of unrefreshing and disturbed sleep are frequently described by ME/CFS patients. This is the first systematic review assessing sleep characteristics in ME/CFS. The aim of this review is to determine whether there are clinical characteristics of sleep in ME/CFS patients compared to healthy controls using objective measures such as polysomnography and multiple sleep latency testing. (2) Methods—the following databases—Pubmed, Embase, Medline (EBSCO host) and Web of Science, were systematically searched for journal articles published between January 1994 to 19 February 2021. Articles that referred to polysomnography or multiple sleep latency testing and ME/CFS patients were selected, and further refined through use of specific inclusion and exclusion criteria. Quality and bias were measured using the Joanna Briggs Institute checklist. (3) Results—twenty observational studies were included in this review. The studies investigated objective measures of sleep quality in ME/CFS. Subjective measures including perceived sleep quality and other quality of life factors were also described. (4) Conclusions— Many of the parameters measured including slow- wave sleep, apnea- hypopnea index, spectral activity and multiple sleep latency testing were inconsistent across the studies. The available research on sleep quality in ME/CFS was also limited by recruitment decisions, confounding factors, small sample sizes and non-replicated findings. Future well-designed studies are required to understand sleep quality in ME/CFS patients.

Download Full-text

Can prolong life with nine turn method (Yan Nian Jiu Zhuan) Qigong alleviates Fatigue, Sleep quality, Depression and anxiety on Patients with Chronic Fatigue Syndrome: a Randomized, Controlled, Clinical Study ?

10.21203/rs.3.rs-965010/v1 ◽

2021 ◽

Author(s):

Fangfang Xie ◽

Jiatuo Xu ◽

Chong Guan ◽

Ziji Cheng ◽

Yuanjia Gu ◽

...

Keyword(s):

Chronic Fatigue Syndrome ◽

Sleep Quality ◽

Chronic Fatigue ◽

Anxiety And Depression ◽

Unknown Etiology ◽

Control Group ◽

Depression And Anxiety ◽

Treatment Groups ◽

Fatigue Syndrome ◽

Wide Range

Abstract Background Chronic fatigue syndrome (CFS) is a complex disease with unknown etiology and mechanism. Prolong life with nine turn method (PLWNT) Qigong is a system of mind-body exercise with restorative benefits that have shown a wide range of benefits in the treatment of CFS. The purpose of this study is to investigate the effect of PLWNT Qigong exercise on CFS with a focus on fatigue, sleep quality, depression and anxiety. Methods A total of 135 participants were randomly divided into treatment groups and control group in the same proportion. The treatment groups received PLWNT Qigong exercise (PLWNT Group) or cognitive behavioral therapy treatment (CBT Group). The healthy control group (HC Group) does not receive any treatment and maintains daily life. Participants from treatment groups were taught by related highly qualified professor at the Shanghai University of Traditional Chinese Medicine once a week and were supervised online during the remaining 6 days at home, over 12 consecutive weeks. The primary outcome was fatigue (MFI-20) and secondary outcomes were sleep quality (PSQI), anxiety and depression (HADS). All groups were measured at baseline (T0) and post-intervention (T1). Results 134 patient completed the study (45 in the PLWNT Group, 44 in the CBT Group and 45 in HC Group). The within group comparison of PLWNT and CBT groups were all showed significant improvement in MFI-20, PSQI and HADS after the intervention (p༜0.05). No significant difference was found between the PLWNT group and CBT group(p༞0.05),but the total effective rate of the PLWNT group was 62.22%, which was higher than the CBT group was 50.00%. The changes in the PLWNT group and CBT group were all higher than those in the HC group except for habitual sleep efficiency and sleep medicine using(p༜0.05). In additional, fatigue degree changes in the PLWBT group were positively correlated with sleep degree (r=0.315) and anxiety degree(r=0.333), but only anxiety degree(r=0.332) was found to be positively correlated with fatigue in the CBT group. Conclusion PLWNT Qigong exercise has the potential as a rehabilitation method on CFS with a focus on fatigue, sleep quality, anxiety and depression. Yet, the results need to be interpreted carefully and needs to be repeated in a larger sample. Future studies will expand the sample size for further in-depth research to determine the frequency and intensity of PLWNT Qigong intervention that is particularly beneficial to CFS. The study registered in the American Clinical Trial Registry on 4 November 2018, the registration number is NCT03496961.

Download Full-text

Subjective sleep quality and association with depression syndrome, chronic diseases and health-related physical fitness in the middle-aged and elderly

BMC Public Health ◽

10.1186/s12889-021-10206-z ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Min-Fang Hsu ◽

Kang-Yun Lee ◽

Tsung-Ching Lin ◽

Wen-Te Liu ◽

Shu-Chuan Ho

Keyword(s):

Depressive Symptoms ◽

Physical Fitness ◽

Sleep Quality ◽

Chronic Diseases ◽

Sleep Latency ◽

Middle Aged ◽

Subjective Sleep Quality ◽

Subjective Sleep ◽

Self Rated Health ◽

Health Related

Abstract Background As a complex phenomenon, sleep quality is difficult to objectively define and measure, and multiple factors related to sleep quality, such as age, lifestyle, physical activity, and physical fitness, feature prominently in older adult populations. The aim of the present study was to evaluate subjective sleep quality using the Pittsburgh Sleep Quality Index (PSQI) and to associate sleep quality with health-related physical fitness factors, depressive symptoms, and the number of chronic diseases in the middle-aged and elderly. Methods We enrolled a total of 283 middle-aged and elderly participants from a rehabilitation clinic or health examination department. The PSQI was used to evaluate sleep quality. The health-related fitness assessment included anthropometric and physical fitness parameters. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale (CES-D) short form. Data were analyzed with SPSS 18.0, and descriptive statistics and logistic regression analysis were used for the analyses. Results Overall, 27.9% of participants in this study demonstrated bad sleepers (with a PSQI score of > 5), 10.2% of study participants frequently used sleep medication to help them fall asleep, and 6.0% reported having significant depressive symptoms (with a CES-D score of ≥10). There are two major findings: (1) depression symptoms, the number of chronic diseases, self-rated health, and arthritis were significantly associated with a poor sleep quality, and (2) the 2-min step test was associated with longer sleep latency. These results confirmed that the 2-min step was associated with a longer sleep latency among the health-related physical fitness items. Conclusions Our study found that depressive syndrome, chronic disease numbers, a poor self-rated health status, and arthritis were the main risk factors that influenced subjective sleep quality.

Download Full-text

Relationship between Perceived Sleep Problems and Thalamic Size in Patients with Chronic Fatigue Syndrome Compared to Non-Fatigued Controls: A Preliminary Study

Clinical Medicine Insights Psychiatry ◽

10.4137/cmpsy.s704 ◽

2008 ◽

Vol 1 ◽

pp. CMPsy.S704

Author(s):

Stefan Begré ◽

Tobias Lütgert ◽

Luca Remonda ◽

Roland Wiest ◽

Claus Kiefer ◽

...

Keyword(s):

Chronic Fatigue Syndrome ◽

Sleep Problems ◽

Chronic Fatigue ◽

Unknown Etiology ◽

Subjective Sleep Quality ◽

Sleep Complaints ◽

Subjective Sleep ◽

Fatigue Syndrome ◽

Post Hoc

Chronic fatigue syndrome (CFS) is characterized by disabling fatigue of unknown etiology. The thalamus is a key subcortical structure in sleep disorders and certain cognitive functions previously shown to be impaired in CFS patients. We investigated the association between subjective sleep quality and thalamic size in CFS. Twelve right-handed CFS patients and 12 age-, gender-, and handedness-matched healthy controls completed the Jenkins Sleep Questionnaire in order to assess subjective sleep problems. Thalamic size was determined by MR-based volumetry. More sleep problems correlated with greater total thalamic volume in patients (rP = 0.62, 95% CI 0.07–0.88, p = 0.032) but not in controls (rP = −0.034, p = 0.30). In post hoc analysis, more sleep problems correlated with right thalamic size in patients (rP = 0.70, 95% CI 0.21–0.91, p = 0.012) but not in controls (rP = −0.080, p = 0.81). Our preliminary results provide a basis for further studies on a possible role of the thalamus in sleep complaints and fatigue of patients with CFS.

Download Full-text

The Association Between Dry Eye Disease With Depression, Anxiety and Sleep Disturbance During COVID-19

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.802302 ◽

2022 ◽

Vol 12 ◽

Author(s):

Qing He ◽

Zhuo Chen ◽

Caiyuan Xie ◽

Lin Liu ◽

Ruihua Wei

Keyword(s):

Sleep Quality ◽

Dry Eye ◽

Sleep Latency ◽

Dry Eye Disease ◽

Eye Disease ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Subjective Sleep Quality ◽

Subjective Sleep ◽

The Relationship

Objective: This study aimed to investigate the relationship between dry eye disease (DED) with anxiety and depression. Additionally, the mediating effect of sleep quality on this relationship was explored.Methods: 321 patients with DED were recruited from Tianjin Medical University Eye Hospital clinic and surveyed using demographic questionnaires, the Ocular Surface Disease Index (OSDI), Hospital Anxiety and Depression Scale (HADS), and Pittsburgh Sleep Quality Index (PSQI). Regression analysis and the bootstrap method were used to investigate the influence of sleep on the relationship between DED, anxiety and depression.Results: Among the patients with DED, 86 (26.79%), 85 (26.48%), and 54 (16.82%) patients presented with anxiety, depression, and both anxiety and depression respectively. The OSDI and PSQI score were positively correlated with depression and anxiety (all p < 0.01). The direct effects of OSDI on depression and anxiety were significant (P < 0.01). Additionally, the bootstrap test showed significant mediating effects of subjective sleep quality [95% CI [0.003–0.016] (depression); [0.001–0.011] (anxiety)] and sleep latency [95% CI [0.001–0.010] (depression); [0.001–0.008] (anxiety)]. These results indicated that the severity of DED symptoms, as measured by the OSDI score, affected anxiety and depression through a direct and an indirect pathway mediated by subjective sleep quality and sleep latency.Conclusions: The results indicated that there was a significant correlation between DED and anxiety and depression. Moreover, subjective sleep quality and sleep latency were a mediator of the relationship between DED symptoms and anxiety and depression.

Download Full-text

Cognitive and behavioral coping in people with Chronic fatigue syndrome: An exploratory study searching for intervention targets for depressive symptoms

Journal of Health Psychology ◽

10.1177/1359105317707259 ◽

2017 ◽

Vol 24 (13) ◽

pp. 1878-1883

Author(s):

Vivian Kraaij ◽

Janneke Bik ◽

Nadia Garnefski

Keyword(s):

Depressive Symptoms ◽

Chronic Fatigue Syndrome ◽

Coping Strategies ◽

Depression Scale ◽

Chronic Fatigue ◽

Anxiety And Depression ◽

Cognitive Coping ◽

Hospital Anxiety ◽

Cognitive Emotion Regulation ◽

Fatigue Syndrome

The aim of the study was to find relevant coping factors for the development of psychological interventions for people with chronic fatigue syndrome who suffer from depressive symptoms. A total of 30 adults with chronic fatigue syndrome filled in the Cognitive Emotion Regulation Questionnaire, the COPE and the Hospital Anxiety and Depression Scale. The findings suggested that cognitive coping strategies have a stronger influence than behavioral coping strategies on depressive symptoms. Especially, the cognitive coping strategies refocusing positive, positive reappraisal and catastrophizing were of importance. These findings suggest that these coping strategies should be part of psychological programs for people with chronic fatigue syndrome.

Download Full-text

Exploratory study into the relationship between the symptoms of chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) and fibromyalgia (FM) using a quasiexperimental design

BMJ Open ◽

10.1136/bmjopen-2020-041947 ◽

2021 ◽

Vol 11 (2) ◽

pp. e041947

Author(s):

Pamela G Mckay ◽

Helen Walker ◽

Colin R Martin ◽

Mick Fleming

Keyword(s):

Quality Of Life ◽

Chronic Fatigue Syndrome ◽

Chronic Fatigue ◽

Myalgic Encephalomyelitis ◽

Anxiety And Depression ◽

Symptom Experience ◽

Fatigue Syndrome ◽

The Impact ◽

The Relationship

ObjectiveTo explore the relationship between symptoms of chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) and fibromyalgia (FM). The hypothesis predicated that there would be no significant differences between the group’s symptom experience.DesignA quasiexperimental design. Structural equation modelling (SEM) and invariance testing.ParticipantsMales (M) and females (F) >16 with a confirmed diagnosis of CFS/ME or FM by a general practitioner or specialist. CFS/ME (n=101, F: n=86, M: n=15, mean (M) age M=45.5 years). FM (n=107, F: n=95, M: n=12, M=47.2 years).Outcome measuresDiagnostic criteria: the American Centers for Disease Control and Prevention (CDC) for CFS/ME and the American College of Rheumatology (ACR) criteria for FM. Additional symptom questionnaires measuring: pain, sleep quality, fatigue, quality of life, anxiety and depression, locus of control and self-esteem.ResultsInvariance was confirmed with the exception of the American CDC Symptom Inventory, Fibromyalgia Impact Questionnaire and Hospital Anxiety and Depression Scale (p<0.05) based on five questions. Consequently, it was erroneous to conclude differences. Therefore, the Syndrome Model was created. SEM could not have tested the ACR previously, as it comprised a single data point. Thus, it was combined with these three questionnaires, increasing the data points, to create this new measurable model. Results confirmed no significant differences between groups (p=0.07 (p<0.05)).ConclusionParticipants responded in a similar manner to the questionnaire, confirming the same symptom experience. It is important to consider this in context with differing criteria and management guidelines, as this may influence diagnosis and the trajectory of patient’s management. With the biomedical cause currently unclear, it is the symptom experience and the impact on quality of life that is important. These findings are meaningful for patients, clinicians and policy development and support the requirement for future research.

Download Full-text