Major Depressive Disorder in Chronic Fatigue Syndrome

2004 ◽  
Vol 12 (3) ◽  
pp. 7-23 ◽  
Author(s):  
Eleanor K. Axe ◽  
Paul Satz ◽  
Natalia L. Rasgon ◽  
Fawzy I. Fawzy
2010 ◽  
Vol 23 (6) ◽  
pp. 643-650 ◽  
Author(s):  
James W. Murrough ◽  
Xiangling Mao ◽  
Katherine A. Collins ◽  
Chris Kelly ◽  
Gizely Andrade ◽  
...  

2009 ◽  
Vol 115 (1-2) ◽  
pp. 46-53 ◽  
Author(s):  
D. Schrijvers ◽  
F. Van Den Eede ◽  
Y. Maas ◽  
P. Cosyns ◽  
W. Hulstijn ◽  
...  

2012 ◽  
Vol 43 (2) ◽  
pp. 375-380 ◽  
Author(s):  
M. Cella ◽  
P. D. White ◽  
M. Sharpe ◽  
T. Chalder

BackgroundSpecific cognitions and behaviours are hypothesized to be important in maintaining chronic fatigue syndrome (CFS). Previous research has shown that a substantial proportion of CFS patients have co-morbid anxiety and/or depression. This study aims to measure the prevalence of specific cognitions and behaviours in patients with CFS and to determine their association with co-morbid anxiety or depression disorders.MethodA total of 640 patients meeting Oxford criteria for CFS were recruited into a treatment trial (i.e. the PACE trial). Measures analysed were: the Cognitive Behavioural Response Questionnaire, the Chalder Fatigue Scale and the Work and Social Adjustment Scale. Anxiety and depression diagnoses were from the Structured Clinical Interview for DSM-IV. Multivariate analysis of variance was used to explore the associations between cognitive-behavioural factors in patients with and without co-morbid anxiety and/or depression.ResultsOf the total sample, 54% had a diagnosis of CFS and no depression or anxiety disorder, 14% had CFS and one anxiety disorder, 14% had CFS and depressive disorder and 18% had CFS and both depression and anxiety disorders. Cognitive and behavioural factors were associated with co-morbid diagnoses; however, some of the mean differences between groups were small. Beliefs about damage and symptom focussing were more frequent in patients with anxiety disorders while embarrassment and behavioural avoidance were more common in patients with depressive disorder.ConclusionsCognitions and behaviours hypothesized to perpetuate CFS differed in patients with concomitant depression and anxiety. Cognitive behavioural treatments should be tailored appropriately.


1999 ◽  
Vol 97 (3) ◽  
pp. 319 ◽  
Author(s):  
D.A. DUPREZ ◽  
M.L. DE BUYZERE ◽  
B. DRIEGHE ◽  
F. VANHAVERBEKE ◽  
Y. TAES ◽  
...  

2017 ◽  
Vol 33 (3) ◽  
pp. 158-165
Author(s):  
Natalia Calvo ◽  
Naia Sáez-Francàs ◽  
Sergi Valero ◽  
Jesús Castro-Marrero ◽  
José Alegre Martín ◽  
...  

Abstract. The study examines the relationship between a categorical and a dimensional personality assessment instrument in patients with Chronic Fatigue Syndrome (CFS). A total of 162 CFS patients were included in the study (91.4% women; mean age 47.5 years). All subjects completed the Spanish versions of the Personality Diagnostic Questionnaire-4+ (PDQ-4+) and the Temperament and Character Inventory-Revised (TCI-R). Results: 78 (48.1%) of the patients presented a Personality Disorder (PD), the most frequent being Cluster C, specifically Obsessive-compulsive disorder, followed by Avoidant disorder. PDs showed a specific pattern of correlation with temperament scales. All PD clusters correlated positively with Harm Avoidance and Self-Transcendence, and negatively with Reward Dependence, Self-Directedness, and Cooperativeness. In a logistic regression analysis, Self-Directedness and Cooperativeness predicted PD presence. The findings are consistent with previous studies in non-CFS samples and suggest that the combination of the Temperament and Character dimensions (low Self-Directedness and Cooperativeness and high Harm Avoidance and Self-Transcendence) correlates with PD severity, and that Self-Directedness and Cooperativeness are associated with PD presence in CFS patients. The integration of these two perspectives expands the current comprehension of personality pathology in CFS patients.


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