scholarly journals Necrotising fasciitis in a patient treated with FOLFIRI-aflibercept for colorectal cancer: a case report

2017 ◽  
Vol 99 (8) ◽  
pp. e225-e226 ◽  
Author(s):  
A Gonzaga-López ◽  
J Muñoz-Rodriguez ◽  
A Ruiz-Casado
Keyword(s):  
Colorectal Cancer ◽  
Case Report ◽  
Folinic Acid ◽  
Rare Complication ◽  
Stage Iv ◽  
Fournier’S Gangrene ◽  
Necrotising Fasciitis ◽  
Fournier's Gangrene ◽  
Rectosigmoid Cancer

Anti-angiogenics have become an important part of the treatment of several types of tumours such as ovarian, breast, lung and colorectal cancer. Necrotising fasciitis has been reported with bevacizumab but no cases have been reported with aflibercept, ramucirumab or regorafenib in patients with colorectal cancer. Necrotising fasciitis is a rare complication affecting one in 5000 bevacizumab users. We report the case of a 64-year-old man with stage IV rectosigmoid cancer under treatment with folinic acid, fluorouracil and irinotecan (FOLFIRI) and aflibercept, who developed a Fournier’s gangrene.

Acquired Penoscrotal Transposition—a Rare Complication of Fournier’s Gangrene—Case Report

2018 ◽  
Vol 81 (3) ◽  
pp. 284-286
Author(s):  
J. S. Rajkumar ◽  
Anirudh Rajkumar ◽  
S. Akbar ◽  
Hema Tadimari ◽  
Dharmendra Kollapalayam Raman ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Complication ◽  
Fournier’S Gangrene ◽  
Fournier's Gangrene ◽  
Penoscrotal Transposition

Fournier's gangrene as Amyand's hernia complication

2019 ◽  
Vol 98 (7) ◽  
pp. 291-296
Keyword(s):  
Case Report ◽  
Case Reports ◽  
Rare Condition ◽  
Sporadic Case ◽  
Fournier’S Gangrene ◽  
Amyand’S Hernia ◽  
Fournier's Gangrene ◽  
Randomized Controlled Studies ◽  
Based Medicine ◽  
Hernia Complication

Introduction: Fournier’s gangrene is a rare but fast deteriorating and serious condition with high mortality. In most cases, it is characterized as necrotizing fasciitis of the perineum and external genitals. Amyand’s hernia is a rare condition where the appendix is contained in the sac of an inguinal hernia. Inflammatory alterations in the appendix account only for 0.1 % of the cases when Amyand’s hernia is verified. Fournier’s gangrene as a complication of a late diagnosis of appendicitis located in the inguinal canal is described in the literature as rare case reports. Case report: The case report of a 70-year-old patient with Fournier’s gangrene resulting from gangrenous appendicitis of Amyand’s hernia. Conclusion: Fournier’s gangrene as a complication of Amyand’s hernia is a rare condition. Only sporadic case reports thereof can be found in the literature. Because of the rarity of this pathology and the lack of randomized controlled studies, it is difficult to determine the optimal treatment according to the principles of evidence-based medicine. An appropriate approach for this condition appears to be the combination of guidelines developed in Amyand’s therapy according to Losanoff and Basson, along with the recommended “gold standard” therapy for Fournier’s gangrene. This means early and highly radical surgical debridement, adequate antibiotic therapy and intensive care.

Fournier's Gangrene of Genitalia: Case Report

2003 ◽  
Vol 70 (1-4) ◽  
pp. 38-40
Author(s):  
P. Salciccia ◽  
G. Poveromo ◽  
S. Salciccia
Keyword(s):  
Septic Shock ◽  
Case Report ◽  
Early Diagnosis ◽  
Rare Disease ◽  
Abdominal Wall ◽  
Sudden Onset ◽  
Fournier’S Gangrene ◽  
Fournier's Gangrene ◽  
Prodromal Symptoms

Fournier's gsngrene is a rare disease involving the scrotum and the penis with occasional extension up to the abdominal wall. The etiology of the disease, commonly without prodromal symptoms and with sudden onset, is still not fully understood. The organisms are usually streptococcus haemoliticus and/or anerobic bacteria. We report a case of Fournier's gangrene, presenting septic shock. The patient was treated with reanimatory care, antibiotics, local excision and debridment. Speaking about anatomical and etiopathogenetic hypotheses, we discuss the diagnostic problems and the treatment of the disease. We emphasize the role of the early diagnosis.

Dangers of delayed diagnosis of perianal abscess and undrained perianal sepsis in Fournier’s gangrene: a case series

2020 ◽  
Vol 13 (10) ◽  
pp. e236503
Author(s):  
Edgardo Solis ◽  
Yi Liang ◽  
Grahame Ctercteko ◽  
James Wei Tatt Toh
Keyword(s):  
Delayed Diagnosis ◽  
Case Series ◽  
Perianal Abscess ◽  
Scoring Systems ◽  
Fournier’S Gangrene ◽  
Necrotising Fasciitis ◽  
Risk Indicator ◽  
Fournier's Gangrene ◽  
Perianal Sepsis

Fournier’s gangrene (FG) is a rapidly progressing infective necrotising fasciitis of the perianal, perineal and genital region. It is characterised by its aggressive nature and high mortality rates of between 15% and 50%. While it has been commonly found to primarily develop from urological sources, there have been increasing reports of the role of colorectal sources as the underlying aetiology of FG. Presented is a case series of four FG presentations at a single institution during a 12-month period as a result of underlying untreated perianal disease highlighting its dangers in progressing to a deadly infection, advocating for early and aggressive surgical debridement, and the role of adjunct scoring systems, such as Laboratory Risk Indicator for Necrotising Fasciitis, in guiding clinical diagnosis.

scholarly journals Fournier's gangrene in a female with spinal cord injury: a case report

Spinal Cord ◽  
2009 ◽  
Vol 48 (3) ◽  
pp. 268-269 ◽  
Author(s):  
V Nigam ◽  
T A Halim ◽  
H S Chhabra
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Case Report ◽  
Fournier’S Gangrene ◽  
Fournier's Gangrene ◽  
Cord Injury

scholarly journals Fournier’s Gangrene in a Patient with Type 2 Diabetes Mellitus Treated with Empagliflozin: A Case Report

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Yasunori Nagano ◽  
Naomi Kashiwagi Yakame ◽  
Hisae Aoki ◽  
Tamaki Yamakawa ◽  
Naoko Iwahashi Kondo
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Case Report ◽  
Fournier’S Gangrene ◽  
Fournier's Gangrene
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