Neglected Tropical Diseases: Infection, Modeling, and Control

2010 ◽  
Vol 21 (1) ◽  
pp. 53-69 ◽  
Author(s):  
Alison Kealey ◽  
Robert Smith
2019 ◽  
Vol 113 (12) ◽  
pp. 839-844 ◽  
Author(s):  
Hannah Kuper

AbstractNeglected tropical diseases (NTDs) are a diverse group of infectious conditions that vary in their epidemiology, impact and control. They are among the most common conditions globally, affecting approximately one billion people. Many NTDs have long-term consequences, such as visual and physical impairments. As a result, people with NTDs may have difficulties in carrying out activities or participating in society—in other words, NTDs can cause disabilities. Additionally, NTDs are often strongly linked to stigma and can have mental health consequences. It is therefore important to incorporate rehabilitation within NTD programmes. Rehabilitation can be conceptualized narrowly in terms of the provision of clinical services (e.g. physiotherapy and assistive devices) or, more broadly, including efforts to improve employment, overcome stigma and enhance social participation of people with disabilities. Approximately 15% of the global population has a disability, and this large group must be considered when designing NTD programmes. Improving the inclusion of people with disabilities may require adaptations to NTD programmes, such as making them physically accessible or training staff about disability awareness. Without incorporating disability within NTD programmes, the quality of life of people with NTDs will suffer and global targets for elimination and management of NTDs will not be met.


2019 ◽  
Vol 27 (1) ◽  
Author(s):  
Lorenzo Zammarchi ◽  
Federico Gobbi ◽  
Andrea Angheben ◽  
Michele Spinicci ◽  
Dora Buonfrate ◽  
...  

Abstract Background In recent years, an increasing number of individuals affected by neglected tropical diseases (NTDs) have been observed in Italy, due to migration, international travels and climate changes. Reliable data on the current NTD epidemiology in Italy and the health system preparedness on this issue are not available. Methods We report the results of a survey on selected NTDs (schistosomiasis, strongyloidiasis, echinococcosis, Chagas disease, leishmaniasis, cysticercosis, filariasis and scabies) in nine Italian sentinel centres, in order to investigate their occurrence throughout the country and identify which ones are a priority for public health interventions, development of protocols for case management, and training activities. To explore the preparedness of the centres, we investigate the availability of specific diagnostic tools and drugs, needed for the management of the most common NTDs. We also reviewed and summarized the available national policies, recommendations and guidelines on NTDs in Italy. Results Overall, 4123 NTDs cases were diagnosed in nine Italian centres within a 7-year period (2011–2017). Schistosomiasis and strongyloidiasis were the most common NTDs, accounting for about one-third each of all the diagnosed cases, followed by Chagas disease. The number of cases showed a significant trend to increase over time, mainly due to foreign-born subjects. Serology for Schistosoma spp. and Strongyloides stercoralis was available in seven and five centres, respectively. Agar plate stool culture for S. stercoralis was available in three sites. Ivermectin and praziquantel were always available in six centres. Six national policies, recommendations and guidelines documents were available, but for the most part, they are not fully implemented yet. Conclusions This survey showed how some NTDs, such as schistosomiasis and strongyloidiasis, are becoming more common in Italy, due to multiple components. A list of seven key actions was proposed, in order to improve diagnosis, management and control of NTDs in Italy.


2016 ◽  
Vol 8 (suppl 1) ◽  
pp. i34-i52 ◽  
Author(s):  
Belete Mengitsu ◽  
Oumer Shafi ◽  
Biruck Kebede ◽  
Fikreab Kebede ◽  
Dagemlidet T. Worku ◽  
...  

2011 ◽  
Vol 5 (10) ◽  
pp. e1222 ◽  
Author(s):  
Derek A. Lobo ◽  
Raman Velayudhan ◽  
Priya Chatterjee ◽  
Harajeshwar Kohli ◽  
Peter J. Hotez

2009 ◽  
Vol 3 (10) ◽  
pp. e537 ◽  
Author(s):  
Hugh J. W. Sturrock ◽  
Diana Picon ◽  
Anthony Sabasio ◽  
David Oguttu ◽  
Emily Robinson ◽  
...  

2020 ◽  
Vol 4 (1) ◽  

Lymphatic filariasis is a neglected tropical diseases, which infection occurs when filarial parasites are transmitted to human through mosquitoes’ bite. In Indonesia, the infection incidence was increased significantly throughout these recent years, it was reported about 6,998 cases in 2004, and whereas in 2018 there were 12,677 cases. Moreover, Indonesian government has conducted two strategies, firstly by applying MDA to reduce the incident rate (mf rate <1%), and secondly by managing and monitoring chronic filariasis patients. However, there were still limited reported studies on the filariasis vector surveillance and control. In this study, we are focus in urban filariasis with Culex quinquefasciatus as the main vector of Wuchereria bancrofti. This mosquito was active during night time, at around 10 pm and 2-4 am, more likely active outdoor rather than indoor, and catched mostly during biting rather than resting activities. Their breeding places were mostly in stagnant and polluted water. In some endemic areas showed the high genetic variation among these mosquitos and defend proteins were detected in positive mosquitos. These proteins present in mosquitos to fight back the filarial parasites.


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