A Quantitative Trait Locus Influencing Activin-to-Estrogen Ratio in Pedigreed Baboons Maps to a Region Homologous to Human Chromosome 19

Human Biology ◽  
2001 ◽  
Vol 73 (6) ◽  
pp. 787-800 ◽  
Author(s):  
Lisa J. Martin ◽  
John Blangero ◽  
Jeffrey Rogers ◽  
Michael C. Mahaney ◽  
James E. Hixson ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Human Chromosome ◽  
Quantitative Trait ◽  
Chromosome 19 ◽  
Trait Locus ◽  
Human Chromosome 19

A quantitative trait locus influencing estrogen levels maps to a region homologous to human chromosome 20

2001 ◽  
Vol 5 (2) ◽  
pp. 75-80 ◽  
Author(s):  
LISA J. MARTIN ◽  
JOHN BLANGERO ◽  
JEFFREY ROGERS ◽  
MICHAEL C. MAHANEY ◽  
JAMES E. HIXSON ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Human Chromosome ◽  
Quantitative Trait ◽  
Potential Candidate ◽  
General Pedigree ◽  
Genome Wide ◽  
A Genome ◽  
Component Approach ◽  
Trait Locus ◽  
Variance Component Approach

Estrogen, a steroid hormone, regulates reproduction and has been implicated in several diseases. We performed a genome-wide scan using multipoint linkage analysis implemented in a general pedigree-based variance component approach to identify genes with measurable effects on variation in estrogen levels in baboons. A microsatellite polymorphism, D20S171, located on human chromosome 20q13.11, showed strong evidence of linkage with a LOD score of 3.06 ( P = 0.00009). This region contains several potential candidate genes including melanocortin 3 receptor ( MC3R), cytochrome P-450 subfamily XXIV ( CYP24), and breast carcinoma amplified sequence ( BCAS1). This is the first evidence of a quantitative trait locus with a significant effect on estrogen.

scholarly journals A Quantitative Trait Locus Influencing Free Plasma Protein S Levels on Human Chromosome 1q

2003 ◽  
Vol 23 (3) ◽  
pp. 508-511 ◽  
Author(s):  
Laura Almasy ◽  
José Manuel Soria ◽  
Juan Carlos Souto ◽  
Imma Coll ◽  
Delphine Bacq ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Human Chromosome ◽  
Plasma Protein ◽  
Quantitative Trait ◽  
Protein S ◽  
Chromosome 1Q ◽  
Trait Locus ◽  
Free Plasma

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

1997 ◽  
Vol 15 (3) ◽  
pp. 273-276 ◽  
Author(s):  
Anthony G. Comuzzie ◽  
James E. Hixson ◽  
Laura Almasy ◽  
Braxton D. Mitchell ◽  
Michael C. Mahaney ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Human Chromosome ◽  
Fat Mass ◽  
Quantitative Trait ◽  
Major Quantitative Trait Locus ◽  
Chromosome 2 ◽  
Serum Leptin ◽  
Trait Locus

Evidence for quantitative trait locus for conformation traits on chromosome 19 in beef cattle

2001 ◽  
Vol 118 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Napolitano ◽  
Catillo ◽  
Lucioli ◽  
Carretta ◽  
Di Giacomo ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Beef Cattle ◽  
Quantitative Trait ◽  
Chromosome 19 ◽  
Trait Locus

scholarly journals Quantitative trait locus determining dietary macronutrient intakes is located on human chromosome 2p22

2004 ◽  
Vol 80 (5) ◽  
pp. 1410-1414 ◽  
Author(s):  
Guowen Cai ◽  
Shelley A Cole ◽  
Raul A Bastarrachea-Sosa ◽  
Jean W MacCluer ◽  
John Blangero ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Human Chromosome ◽  
Quantitative Trait ◽  
Trait Locus

Influence of a Quantitative Trait Locus on Mouse Chromosome 19 to the Light-Adapted Electroretinogram

2008 ◽  
Vol 49 (9) ◽  
pp. 4058 ◽  
Author(s):  
Alison L. Reynolds ◽  
Michael Danciger ◽  
G. Jane Farrar ◽  
Peter Humphries ◽  
Paul F. Kenna
Keyword(s):  
Quantitative Trait Locus ◽  
Mouse Chromosome ◽  
Quantitative Trait ◽  
Chromosome 19 ◽  
Trait Locus
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