scholarly journals A Quantitative Trait Locus Influencing Free Plasma Protein S Levels on Human Chromosome 1q

2003 ◽  
Vol 23 (3) ◽  
pp. 508-511 ◽  
Author(s):  
Laura Almasy ◽  
José Manuel Soria ◽  
Juan Carlos Souto ◽  
Imma Coll ◽  
Delphine Bacq ◽  
...  
Human Biology ◽  
2001 ◽  
Vol 73 (6) ◽  
pp. 787-800 ◽  
Author(s):  
Lisa J. Martin ◽  
John Blangero ◽  
Jeffrey Rogers ◽  
Michael C. Mahaney ◽  
James E. Hixson ◽  
...  

2001 ◽  
Vol 5 (2) ◽  
pp. 75-80 ◽  
Author(s):  
LISA J. MARTIN ◽  
JOHN BLANGERO ◽  
JEFFREY ROGERS ◽  
MICHAEL C. MAHANEY ◽  
JAMES E. HIXSON ◽  
...  

Estrogen, a steroid hormone, regulates reproduction and has been implicated in several diseases. We performed a genome-wide scan using multipoint linkage analysis implemented in a general pedigree-based variance component approach to identify genes with measurable effects on variation in estrogen levels in baboons. A microsatellite polymorphism, D20S171, located on human chromosome 20q13.11, showed strong evidence of linkage with a LOD score of 3.06 ( P = 0.00009). This region contains several potential candidate genes including melanocortin 3 receptor ( MC3R), cytochrome P-450 subfamily XXIV ( CYP24), and breast carcinoma amplified sequence ( BCAS1). This is the first evidence of a quantitative trait locus with a significant effect on estrogen.


1997 ◽  
Vol 15 (3) ◽  
pp. 273-276 ◽  
Author(s):  
Anthony G. Comuzzie ◽  
James E. Hixson ◽  
Laura Almasy ◽  
Braxton D. Mitchell ◽  
Michael C. Mahaney ◽  
...  

2008 ◽  
Vol 84 (2) ◽  
pp. 75-84 ◽  
Author(s):  
John R. Shaffer ◽  
Candace M. Kammerer ◽  
Jan M. Bruder ◽  
Shelley A. Cole ◽  
Thomas D. Dyer ◽  
...  

2004 ◽  
Vol 80 (5) ◽  
pp. 1410-1414 ◽  
Author(s):  
Guowen Cai ◽  
Shelley A Cole ◽  
Raul A Bastarrachea-Sosa ◽  
Jean W MacCluer ◽  
John Blangero ◽  
...  

BMC Genomics ◽  
2004 ◽  
Vol 5 (1) ◽  
Author(s):  
James Close ◽  
Laurence Game ◽  
Barnaby Clark ◽  
Jean Bergounioux ◽  
Ageliki Gerovassili ◽  
...  

2005 ◽  
Vol 14 (21) ◽  
pp. 3141-3148 ◽  
Author(s):  
Claire A. Parsons ◽  
H. Joel Mroczkowski ◽  
Fiona E.A. McGuigan ◽  
Omar M.E. Albagha ◽  
Stavros Manolagas ◽  
...  

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