Detection of biomolecules and bioconjugates by monitoring rotated grating-coupled surface plasmon resonance

Localized surface plasmon resonance (LSPR) is induced by incident light when it interacts with noble metal nanoparticles that have smaller sizes than the wavelength of the incident light. Recently, LSPR-based nanobiosensors were developed as tools for highly sensitive, label-free, and flexible sensing techniques for the detection of biomolecular interactions. In this paper, we describe the basic principles of LSPR-based nanobiosensing techniques and LSPR sensor system for biomolecule sensing. We also discuss the challenges using LSPR nanobiosensors for detection of biomolecules as a biomarker.

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Highly sensitive detection of biomolecules with the magneto-optic surface-plasmon-resonance sensor

Optics Letters ◽

10.1364/ol.31.001085 ◽

2006 ◽

Vol 31 (8) ◽

pp. 1085 ◽

Cited By ~ 194

Author(s):

B. Sepúlveda ◽

A. Calle ◽

L. M. Lechuga ◽

G. Armelles

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Sensitive Detection ◽

Surface Plasmon Resonance Sensor ◽

Highly Sensitive ◽

Resonance Sensor ◽

Detection Of Biomolecules ◽

Highly Sensitive Detection ◽

Magneto Optic

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Study of Computational Theory of Surface Plasmon Resonance (SPR) for Porcine Gelatin Detected Sensor Based Nanomaterial Fe3O4–CNT in Otto’s Configuration

Proceeding International Conference on Science and Engineering ◽

10.14421/icse.v1.279 ◽

2017 ◽

Vol 1 ◽

pp. 115-124

Author(s):

Maulina Lutfiyah ◽

Asih Melati

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Laser Light ◽

Metal Layer ◽

Biomolecular Detection ◽

Computational Theory ◽

Gelatin Layer ◽

Detection Of Biomolecules ◽

Angular Shift

Accurate biomolecular detection can be performed through the Surface Plasmon Resonance (SPR) phenomenon. This study was conducted to determine the effect of the addition of Fe3O4 and Carbon Nanotube (CNT) nanomaterials in the Otto configurations and their use as porcine detection sensors. The research was conducted theoretically by finding the equation of reflectance and computationally using Matlab software version 7.12.0 to know SPR angle and reflectance value. This research uses ATR method with Otto configuration. The modeling was finished using HeNe laser light on 632.8 nm wavelength, semi-circle prism type BK7, metal layer of gold nanoparticles. The results of the research can be used in the detection of porcine gelatin by Otto configurations. The best air gap thickness is 30 nm. The best thickness of the gold layer and Fe3O4 layer are 50 nm and 0.05 nm. The applied of MWCNT nanoparticles is not effective in the detection of biomolecules based SPR. While the thickness of SWCNT used is 1 nm. The SWCNT material also proved to be better used in SPR systems. The addition of porcine gelatin layer in the system shows a graphic change in the form of increasing reflectance value and SPR angular shift.

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