Simultaneous Determination of Tramadol and Ibuprofen in Pharmaceutical Preparations by First Order Derivative Spectrophotometric and LC Methods

2008 ◽  
Vol 68 (9-10) ◽  
pp. 843-847 ◽  
Author(s):  
A. B. Thomas ◽  
N. G. Dumbre ◽  
R. K. Nanda ◽  
L. P. Kothapalli ◽  
A. A. Chaudhari ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Vu Dang Hoang ◽  
Dong Thi Ha Ly ◽  
Nguyen Huu Tho ◽  
Hue Minh Thi Nguyen

The application of first-order derivative and wavelet transforms to UV spectra and ratio spectra was proposed for the simultaneous determination of ibuprofen and paracetamol in their combined tablets. A new hybrid approach on the combined use of first-order derivative and wavelet transforms to spectra was also discussed. In this application, DWT (sym6 and haar), CWT (mexh), and FWT were optimized to give the highest spectral recoveries. Calibration graphs in the linear concentration ranges of ibuprofen (12–32 mg/L) and paracetamol (20–40 mg/L) were obtained by measuring the amplitudes of the transformed signals. Our proposed spectrophotometric methods were statistically compared to HPLC in terms of precision and accuracy.


2009 ◽  
Vol 25 (4) ◽  
pp. 487-492 ◽  
Author(s):  
Vitor C. ALMEIDA ◽  
Alexandro M. M. VARGAS ◽  
Juliana C. GARCIA ◽  
Ervim LENZI ◽  
Cláudio C. OLIVEIRA ◽  
...  

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