scholarly journals Correction: Contrast Enhanced Micro-Computed Tomography Resolves the 3-Dimensional Morphology of the Cardiac Conduction System in Mammalian Hearts

PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
Author(s):  
Robert S. Stephenson ◽  
Mark R. Boyett ◽  
George Hart ◽  
Theodora Nikolaidou ◽  
Xue Cai ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Conduction System ◽  
Cardiac Conduction ◽  
Cardiac Conduction System ◽  
Micro Computed Tomography ◽  
3 Dimensional ◽  
Contrast Enhanced

scholarly journals Contrast Enhanced Micro-Computed Tomography Resolves the 3-Dimensional Morphology of the Cardiac Conduction System in Mammalian Hearts

PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. e35299 ◽  
Author(s):  
Robert S. Stephenson ◽  
Mark R. Boyett ◽  
George Hart ◽  
Theodora Nikolaidou ◽  
Xue Cai ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Conduction System ◽  
Cardiac Conduction ◽  
Cardiac Conduction System ◽  
Micro Computed Tomography ◽  
3 Dimensional ◽  
Contrast Enhanced

scholarly journals 21 Contrast Enhanced Micro-Computed Tomography Resolves the 3-Dimensional Morphology of the Cardiac Conduction System in Mammalian Hearts

Heart ◽  
2012 ◽  
Vol 98 (Suppl 3) ◽  
pp. A7.1-A7
Author(s):  
S Robert ◽  
Stephenson ◽  
R Mark Boyett ◽  
George Hart ◽  
Theodora Nikolaidou ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Conduction System ◽  
Cardiac Conduction ◽  
Cardiac Conduction System ◽  
Micro Computed Tomography ◽  
3 Dimensional ◽  
Contrast Enhanced

scholarly journals High-Resolution Contrast-Enhanced Micro-Computed Tomography to Identify the Cardiac Conduction System in Congenitally Malformed Hearts

2018 ◽  
Vol 11 (11) ◽  
pp. 1706-1712 ◽  
Author(s):  
Robert S. Stephenson ◽  
Caroline B. Jones ◽  
Rafael Guerrero ◽  
Jichao Zhao ◽  
Robert H. Anderson ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Conduction System ◽  
Cardiac Conduction ◽  
Cardiac Conduction System ◽  
Micro Computed Tomography ◽  
Contrast Enhanced

scholarly journals High resolution 3-Dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Robert S. Stephenson ◽  
Andrew Atkinson ◽  
Petros Kottas ◽  
Filip Perde ◽  
Fatemeh Jafarzadeh ◽  
...  
Keyword(s):  
Mathematical Modeling ◽  
High Resolution ◽  
Conduction System ◽  
Cardiac Conduction ◽  
Cardiac Conduction System ◽  
3 Dimensional

Molecular Profiling of the Cardiac Conduction System: the Dawn of a New Era

2021 ◽  
Vol 23 (8) ◽  
Author(s):  
Sruthi Mantri ◽  
Sean M. Wu ◽  
William R. Goodyer
Keyword(s):  
Molecular Profiling ◽  
Conduction System ◽  
Cardiac Conduction ◽  
Cardiac Conduction System ◽  
New Era

scholarly journals Sudden Unexpected Death Associated with Arrhythmogenic Cardiomyopathy: Study of the Cardiac Conduction System

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1323
Author(s):  
Giulia Ottaviani ◽  
Graziella Alfonsi ◽  
Simone G. Ramos ◽  
L. Maximilian Buja
Keyword(s):  
Fibromuscular Dysplasia ◽  
Ventricular Myocardium ◽  
Conduction System ◽  
Cardiac Conduction ◽  
Future Research ◽  
Cardiac Conduction System ◽  
Arrhythmogenic Cardiomyopathy ◽  
Unexpected Death ◽  
The Past ◽  
The Right

A retrospective study was conducted on pathologically diagnosed arrhythmogenic cardiomyopathy (ACM) from consecutive cases over the past 34 years (n = 1109). The anatomo-pathological analyses were performed on 23 hearts diagnosed as ACM (2.07%) from a series of 1109 suspected cases, while histopathological data of cardiac conduction system (CCS) were available for 15 out of 23 cases. The CCS was removed in two blocks, containing the following structures: Sino-atrial node (SAN), atrio-ventricular junction (AVJ) including the atrio-ventricular node (AVN), the His bundle (HB), the bifurcation (BIF), the left bundle branch (LBB) and the right bundle branch (RBB). The ACM cases consisted of 20 (86.96%) sudden unexpected cardiac death (SUCD) and 3 (13.04%) native explanted hearts; 16 (69.56%) were males and 7 (30.44%) were females, ranging in age from 5 to 65 (mean age ± SD, 36.13 ± 16.06) years. The following anomalies of the CCS, displayed as percentages of the 15 ACM SUCD cases in which the CCS has been fully analyzed, have been detected: Hypoplasia of SAN (80%) and/or AVJ (86.67%) due to fatty-fibrous involvement, AVJ dispersion and/or septation (46.67%), central fibrous body (CFB) hypoplasia (33.33%), fibromuscular dysplasia of SAN (20%) and/or AVN (26.67%) arteries, hemorrhage and infarct-like lesions of CCS (13.33%), islands of conduction tissue in CFB (13.33%), Mahaim fibers (13.33%), LBB block by fibrosis (13.33%), AVN tongue (13.33%), HB duplicity (6.67%%), CFB cartilaginous meta-hyperplasia (6.67%), and right sided HB (6.67%). Arrhythmias are the hallmark of ACM, not only from the fatty-fibrous disruption of the ventricular myocardium that accounts for reentrant ventricular tachycardia, but also from the fatty-fibrous involvement of CCS itself. Future research should focus on application of these knowledge on CCS anomalies to be added to diagnostic criteria or at least to be useful to detect the patients with higher sudden death risks.

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