scholarly journals Increased Expression of Neurotrophin 4 Following Focal Cerebral Ischemia in Adult Rat Brain with Treadmill Exercise

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e52461 ◽  
Author(s):  
Jin-Young Chung ◽  
Min-Wook Kim ◽  
Moon-Suk Bang ◽  
Manho Kim
2015 ◽  
Vol 245 ◽  
pp. 44-57 ◽  
Author(s):  
Amelia R. Van Slooten ◽  
Yuhui Sun ◽  
Andrew N. Clarkson ◽  
Bronwen J. Connor

Stroke ◽  
2008 ◽  
Vol 39 (10) ◽  
pp. 2837-2844 ◽  
Author(s):  
Shang-Wei Hou ◽  
Yong-Quan Wang ◽  
Ming Xu ◽  
Di-Han Shen ◽  
Ji-Jiang Wang ◽  
...  

2009 ◽  
Vol 55 (7) ◽  
pp. 629-636 ◽  
Author(s):  
Yong-Quan Wang ◽  
Hui-Ru Cui ◽  
Shan-Zheng Yang ◽  
Hua-Ping Sun ◽  
Mei-Hong Qiu ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Jin-Young Chung ◽  
Min-Wook Kim ◽  
Wooseok Im ◽  
In Koo Hwang ◽  
Moon-Suk Bang ◽  
...  

Neurotrophin-3 (NT-3) is a neurotrophic factor that mainly binds to the tyrosine kinase C (trkC) receptor. NT-3 has been shown to have neuroprotective effects in focal cerebral ischemia. Exercise also has ability to induce functional recovery in focal cerebral ischemia. However, the relationship between NT-3, its receptor trkC, and exercise has not been revealed. In this study, we assessed the expressions of NT-3 and trkC in focal cerebral ischemia. We also assessed the expression of NT-3 and trkC with treadmill exercise in focal cerebral ischemia. The results showed that, in a permanent middle cerebral artery occlusion rat model, exercise increased NT-3 and trkC expression. However, the patterns of expression of NT-3 and trkC at different time points varied. These results suggest that exercise-induced functional recovery in focal cerebral ischemia was related to NT-3 and trkC, but the role on times of NT-3 and trkC differed, although trkC is the receptor kinase for NT-3.


2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S217-S217
Author(s):  
Kentaro Deguchi ◽  
Mikiro Takaishi ◽  
Takeshi Hayashi ◽  
Atsuhiko Oohira ◽  
Shoko Nagotani ◽  
...  

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