scholarly journals Differentiating Coeliac Disease from Irritable Bowel Syndrome by Urinary Volatile Organic Compound Analysis – A Pilot Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e107312 ◽  
Author(s):  
Ramesh P. Arasaradnam ◽  
Eric Westenbrink ◽  
Michael J. McFarlane ◽  
Ruth Harbord ◽  
Samantha Chambers ◽  
...  
Gut ◽  
2014 ◽  
Vol 63 (Suppl 1) ◽  
pp. A110.1-A110
Author(s):  
J Covington ◽  
M McFarlane ◽  
R Harbord ◽  
E Westenbrink ◽  
S Chambers ◽  
...  

2014 ◽  
Vol 146 (5) ◽  
pp. S-472-S-473
Author(s):  
James Covington ◽  
Ruth Harbord ◽  
Eric W. Westenbrink ◽  
Samantha Chambers ◽  
Michael McFarlane ◽  
...  

2016 ◽  
Vol 10 (1) ◽  
pp. 016012 ◽  
Author(s):  
R P Arasaradnam ◽  
M McFarlane ◽  
K Ling ◽  
S Wurie ◽  
N O’Connell ◽  
...  

2020 ◽  
Vol 14 ◽  
pp. 117863021989087
Author(s):  
Donna Auguste ◽  
Shelly L Miller

Volatile organic compounds (VOCs) are emitted from a variety of household and personal care products. Many VOCs are known to be potentially toxic or carcinogenic. Synthetic hair is used in hair-styling practices, including practices in African American communities that involve singeing or heating the synthetic hair. The research questions that we sought to answer were as follows: Are VOCs emitted from singed or heated synthetic hair? If so, what are the VOC species and relative masses identified in singed or heated synthetic hair? We tested samples from 2 sources of singed and heated synthetic hair in a microchamber; one source was flame-retardant synthetic hair and the other source was non-flame-retardant synthetic hair. Our findings confirmed that VOCs are emitted from singed or heated synthetic hair for both types of sources. For flame-retardant synthetic hair, we identified and measured mass for species that included acetone, acetonitrile, 2-butanone, benzene, chloromethane, chloroethane, and 1,2-dichloroethane. For non-flame-retardant synthetic hair, we identified and measured mass for species that included acetone, acetonitrile, chloromethane, trichlorofluoromethane, and 2-propanol.


Bioanalysis ◽  
2013 ◽  
Vol 5 (18) ◽  
pp. 2239-2247 ◽  
Author(s):  
Florian Gahleitner ◽  
Cristina Guallar-Hoyas ◽  
Caroline S Beardsmore ◽  
Hitesh C Pandya ◽  
CL Paul Thomas

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 755
Author(s):  
Rachael Slater ◽  
Alessandra Frau ◽  
Jane Hodgkinson ◽  
Debra Archer ◽  
Chris Probert

Anoplocephala perfoliata is a common equine tapeworm associated with an increased risk of colic (abdominal pain) in horses. Identification of parasite and intestinal microbiota interactions have consequences for understanding the mechanisms behind parasite-associated colic and potential new methods for parasite control. A. perfoliata was diagnosed by counting of worms in the caecum post-mortem. Bacterial DNA was extracted from colonic contents and sequenced targeting of the 16S rRNA gene (V4 region). The volatile organic compound (VOC) metabolome of colonic contents was characterised using gas chromatography mass spectrometry. Bacterial diversity (alpha and beta) was similar between tapeworm infected and non-infected controls. Some compositional differences were apparent with down-regulation of operational taxonomic units (OTUs) belonging to the symbiotic families of Ruminococcaceae and Lachnospiraceae in the tapeworm-infected group. Overall tapeworm burden accounted for 7–8% of variation in the VOC profile (permutational multivariate analysis of variance). Integration of bacterial OTUs and VOCs demonstrated moderate to strong correlations indicating the potential of VOCs as markers for bacterial OTUs in equine colonic contents. This study has shown potential differences in the intestinal microbiome and metabolome of A. perfoliata infected and non-infected horses. This pilot study did not control for extrinsic factors including diet, disease history and stage of infection.


2016 ◽  
Vol 10 (4) ◽  
pp. 046012 ◽  
Author(s):  
H J Martin ◽  
M A Turner ◽  
S Bandelow ◽  
L Edwards ◽  
Svetlana Riazanskaia ◽  
...  

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