scholarly journals Alphavirus Replicon DNA Expressing HIV Antigens Is an Excellent Prime for Boosting with Recombinant Modified Vaccinia Ankara (MVA) or with HIV gp140 Protein Antigen

PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0117042 ◽  
Author(s):  
Maria L. Knudsen ◽  
Karl Ljungberg ◽  
Roger Tatoud ◽  
Jonathan Weber ◽  
Mariano Esteban ◽  
...  
Keyword(s):  
Protein Antigen

scholarly journals Physicochemical Characterization Cascade of Nanoadjuvant–Antigen Systems for Improving Vaccines

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 544
Author(s):  
Giuditta Guerrini ◽  
Antonio Vivi ◽  
Sabrina Gioria ◽  
Jessica Ponti ◽  
Davide Magrì ◽  
...  
Keyword(s):  
Immune Response ◽  
Protein Structure ◽  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Protein Antigen ◽  
Efficacy And Safety

Adjuvants have been used for decades to enhance the immune response to vaccines, in particular for the subunit-based adjuvants. Physicochemical properties of the adjuvant-protein antigen complexes, such as size, morphology, protein structure and binding, influence the overall efficacy and safety of the vaccine. Here we show how to perform an accurate physicochemical characterization of the nanoaluminum–ovalbumin complex. Using a combination of existing techniques, we developed a multi-staged characterization strategy based on measurements of increased complexity. This characterization cascade has the advantage of being very flexible and easily adaptable to any adjuvant-protein antigen combinations. It will contribute to control the quality of antigen–adjuvant complexes and immunological outcomes, ultimately leading to improved vaccines.

scholarly journals Design and immunological properties of topographic immunogenic determinants of a protein antigen (LDH-C4) as vaccines.

1992 ◽  
Vol 267 (9) ◽  
pp. 6338-6346
Author(s):  
P.T. Kaumaya ◽  
A.M. VanBuskirk ◽  
E Goldberg ◽  
S.K. Pierce
Keyword(s):  
Protein Antigen ◽  
Immunological Properties

scholarly journals Mechanism of Thimerosal-Induced Structural Destabilization of a Recombinant Rotavirus P[4] Protein Antigen Formulated as a Multi-Dose Vaccine

2020 ◽  
Author(s):  
Kawaljit Kaur ◽  
Jian Xiong ◽  
Nishant Sawant ◽  
Sanjeev Agarwal ◽  
John M. Hickey ◽  
...  
Keyword(s):  
Protein Antigen ◽  
Dose Vaccine

Molecular detection andin vivo analysis of the specific T cell response to a protein antigen

1992 ◽  
Vol 22 (10) ◽  
pp. 2639-2647 ◽  
Author(s):  
Madeleine Cochet ◽  
Christophe Pannetier ◽  
Armelle Regnault ◽  
Sylvie Darche ◽  
Claude Leclerc ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Response ◽  
Molecular Detection ◽  
T Cell Response ◽  
Protein Antigen

scholarly journals Localization on the cell surface of streptococcal protein antigen A

1994 ◽  
Vol 118 (1-2) ◽  
pp. 175-1739
Author(s):  
Robert G. Holt ◽  
Howard J. Wynder
Keyword(s):  
Cell Surface ◽  
Protein Antigen ◽  
Antigen A

Expression of viral capsid protein antigen against Epstein-Barr virus in plastids ofNicotiana tabacum cv. SR1

2006 ◽  
Vol 94 (6) ◽  
pp. 1129-1137 ◽  
Author(s):  
Maggie Y.T. Lee ◽  
Yuanxiang Zhou ◽  
Raymond W.M. Lung ◽  
Mee-Len Chye ◽  
Wing-Kin Yip ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Epstein Barr Virus ◽  
Protein Antigen ◽  
Viral Capsid ◽  
Viral Capsid Protein ◽  
Barr Virus ◽  
Ofnicotiana Tabacum ◽  
Epstein Barr
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