scholarly journals Uptake of Mass Drug Administration Programme for Schistosomiasis Control in Koome Islands, Central Uganda

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0123673 ◽  
Author(s):  
Doreen Tuhebwe ◽  
James Bagonza ◽  
Elizabeth Ekirapa Kiracho ◽  
Adoke Yeka ◽  
Alison M. Elliott ◽  
...  
2021 ◽  
Author(s):  
Mhlengi Vella Ncube ◽  
Tafadzwa Mindu ◽  
Moses John Chimbari

Abstract Background: Children aged five years and below in schistosomiasis endemic areas spend several years living with the schistosome infections before they can be treated as they are excluded from school based mass drug administration programs. The WHO has recommended that these children be included in schistosomiasis preventive chemotherapy in endemic areas. Including these children in schistosomiasis control mass drug administration programs is a complicated task involving translating clinical studies into clinical practice processes, contextualizing clinical practice processes to the resources that are available in the community and economic evaluations. Methodology: We conducted a scoping search on google scholar and the concepts we searched for included implementation strategies, contextualization strategies, resource planning and economic evaluations in health care, risk and quality assessments. We then developed a conceptual framework and explained how the conceptual framework could be used to develop an implementation strategy for a mass drug administration for children aged five year and belowResults: The most common methods/frameworks that were identified in our search for health care implementation strategy development include the following: Donabedian framework, scoping review, FMEA, scenario planning, resource planning and economic evaluation of healthcare interventions and cost-effectiveness analysis.Conclusion: We concluded that the Donabedian framework can be modified and used in conjunction with scoping reviews, FMEA, scenario planning and economic evaluations to develop an implementation strategy for a schistosomiasis control MDA program for children aged five years old and below.


F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 1157 ◽  
Author(s):  
W. Evan Secor

Mass drug administration using praziquantel is the backbone of the current strategy for the control of schistosomiasis. As the theoretical plans have moved into practical application, certain challenges with this approach have surfaced, and it is likely that annual mass drug administration alone may not be sufficient to achieve program goals. However, mass drug administration is still the only available intervention that can be readily used in the wide variety of settings where schistosomiasis is endemic. The task then becomes how to improve this approach and identify what adjuncts to mass drug administration are effective, as programs move from morbidity control to elimination goals. Other aspects worthy of consideration include how best to employ new diagnostic tools to more easily identify where treatment is needed, and new formulations of praziquantel to extend the availability of treatment to all age groups. The aim of this review is to highlight both areas of challenge and of opportunity to improve the public health impact of schistosomiasis control programs.


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