scholarly journals Association of the urinary sodium to urinary specific gravity ratio with metabolic syndrome in Korean children and adolescents: The Korea National Health and Nutrition Examination Survey 2010-2013

PLoS ONE ◽  
2017 ◽  
Vol 12 (12) ◽  
pp. e0189934 ◽  
Author(s):  
Cheol Hwan So ◽  
Hwal Rim Jeong ◽  
Young Suk Shim
Keyword(s):  
Metabolic Syndrome ◽  
Specific Gravity ◽  
Children And Adolescents ◽  
National Health ◽  
Urinary Sodium ◽  
Nutrition Examination Survey ◽  
Korean Children ◽  
Health And Nutrition ◽  
Urinary Specific Gravity

Association of sodium intake with insulin resistance in Korean children and adolescents: the Korea National Health and Nutrition Examination Survey 2010

2018 ◽  
Vol 31 (2) ◽  
pp. 117-125 ◽  
Author(s):  
Yong Min Kim ◽  
So Hyun Kim ◽  
Young Suk Shim
Keyword(s):  
Insulin Resistance ◽  
Children And Adolescents ◽  
National Health ◽  
Sodium Intake ◽  
Urinary Sodium ◽  
Nutrition Examination Survey ◽  
Creatinine Ratio ◽  
Korean Children ◽  
Urinary Creatinine ◽  
Health And Nutrition

Abstract Background: This study aimed to evaluate the relationship between sodium intake and insulin resistance indices. Methods: A total of 718 Korean children and adolescents (411 boys) aged 10–18 years who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) were included in the study. The urinary sodium to urinary creatinine ratio was used as a surrogate for sodium intake. The homeostatic model assessment of insulin resistance (HOMA-IR) and the quantitative insulin sensitivity check index (QUICKI) were used as indices of insulin resistance. Results: The mean urinary sodium to urinary creatinine ratio was 11.34 in males and 10.17 in females. The urinary sodium to urinary creatinine ratio was significantly positively correlated with HOMA-IR (r=0.165, p<0.001) and inversely correlated with QUICKI (r=−0.181, p<0.001) in Pearson’s correlation analyses. In a multivariate linear regression analysis, the urinary sodium to urinary creatinine ratio was independently and significantly positively associated with HOMA-IR (β=0.073, p=0.018) and significantly inversely associated with QUICKI (β=−0.080, p=0.007) after adjustment for possible confounders. HOMA-IR was independently and significantly positively associated with the urinary sodium to urinary creatinine ratio (β=0.087, p=0.018), whereas QUICKI was independently and significantly negatively associated with the urinary sodium to urinary creatinine ratio (β=−0.097, p=0.009) after controlling for confounders. Conclusions: Our results suggest that sodium intake, as estimated by the urinary sodium to urinary creatinine ratio, may be independently associated with insulin resistance in children and adolescents.

scholarly journals Blood Mercury Levels in Relation to Overweight in Korean Children and Adolescents: Results From The Korean National Health and Nutrition Examination Survey 2010-2013

2021 ◽  
Author(s):  
KY YOUNG CHO
Keyword(s):  
Children And Adolescents ◽  
National Health ◽  
Mercury Level ◽  
Overweight And Obesity ◽  
Mercury Exposure ◽  
Seafood Consumption ◽  
Nutrition Examination Survey ◽  
Korean Children ◽  
Health And Nutrition ◽  
Blood Mercury

Abstract Background: Previous researches for adults have demonstrated a substantial role of mercury exposure in the development of overweight and obesity development, but those findings are inconsistent. Although children and adolescents are more susceptible to the toxic effect of mercury compared to adults, the research of overweight and obesity related to mercury exposure in children and adolescent is scarce. This study aimed to investigate the association of blood mercury levels with body mass index (BMI) in Korean children and adolescents.Methods: The cross-sectional data analyzed were obtained from 1327 participants (age: 10-18 years, 672 males and 655 females) who completed the Korean National Health and Nutrition Examination Survey 2010-2013. The adjusted covariates were age, sex, household income, total intake of seafood in the previous 24 hours, and current status of alcohol consumption and smoking. Results: The adjusted geometric mean blood mercury level was 2.19 µg/L and increased significantly in the overweight group and the highest seafood consumption quartile compared with the level in the normal weight group and lowest seafood consumption quartile, respectively (P < 0.001). The adjusted blood mercury levels were significantly positively correlated with BMI in all participants and females (P < 0.05). When stratified by age and sex, all participants and males in the highest blood mercury level quartile were at higher risk of overweight than those in the lowest quartile (odds ratios [95% confidential intervals, CIs]: 1.78 [1.06-2.98], and 2.06 [1.01-4.23], respectively) after adjusting for the covariates (P < 0.05). Receiver operating characteristic analysis of blood mercury levels for predicting overweight revealed that the area under the curve was 0.603 (P < 0.001).Conclusions: Our study suggested a significant association between mercury exposure and the risk of overweight in Korean children and adolescents.

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