scholarly journals A protocol for rapid monocyte isolation and generation of singular human monocyte-derived dendritic cells

PLoS ONE ◽  
2020 ◽  
Vol 15 (4) ◽  
pp. e0231132 ◽  
Author(s):  
Thaize Quiroga Chometon ◽  
Mariana da Silva Siqueira ◽  
Julie Carmo Sant´anna ◽  
Matheus Rogério Almeida ◽  
Mariana Gandini ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Human Monocyte ◽  
Monocyte Isolation

scholarly journals Human monocyte isolation methods influence cytokine production from in vitro generated dendritic cells

Immunology ◽  
2005 ◽  
Vol 114 (2) ◽  
pp. 204-212 ◽  
Author(s):  
Eyad Elkord ◽  
Paul E. Williams ◽  
Howard Kynaston ◽  
Anthony W. Rowbottom
Keyword(s):  
Dendritic Cells ◽  
Cytokine Production ◽  
Human Monocyte ◽  
Isolation Methods ◽  
Monocyte Isolation

scholarly journals Human Herpesvirus 6A Induces Dendritic Cell Death and HMGB1 Release without Virus Replication

Pathogens ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 57
Author(s):  
Rasmus Gustafsson
Keyword(s):  
Cell Death ◽  
Dendritic Cells ◽  
High Mobility ◽  
Human Herpesvirus ◽  
Human Monocyte ◽  
Hmgb1 Protein ◽  
Innate And Adaptive Immunity ◽  
Th2 Polarization ◽  
Dependent Cell ◽  
Ifn Γ

Human herpesvirus 6A (HHV-6A) is a common virus that has important immunomodulatory effects. Dendritic cells (DC) are key players in innate and adaptive immunity and are implicated in the pathogenesis of many human diseases, including infections. (1) Background: Previous studies have demonstrated suppressive effects of HHV-6A on key DC functions. (2) Methods: human monocyte derived dendritic cells were inoculated with HHV-6A and viral replication, cell viability, and release of high mobility group box 1 (HMGB1) protein from DC and of the cytokines IL-2, IL-4, IL-6, IL-10, TNF and IFN-γ after co-culture with allogenic CD4+ T cells were assessed. (3) Results: Nonproductive infection of HHV-6A in DC leads to titer-dependent cell death and the release of HMGB1 protein, and a Th2 polarization. (4) Conclusion: These immune responses aimed to clear the infection may also imply risks for inflammatory pathologies associated with HHV-6A such as multiple sclerosis.

scholarly journals IFN-γ and R-848 Dependent Activation of Human Monocyte-Derived Dendritic Cells by Neisseria meningitidis Adhesin A

2007 ◽  
Vol 179 (6) ◽  
pp. 3904-3916 ◽  
Author(s):  
Cristina Mazzon ◽  
Barbara Baldani-Guerra ◽  
Paola Cecchini ◽  
Tihana Kasic ◽  
Antonella Viola ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Neisseria Meningitidis ◽  
Human Monocyte ◽  
Ifn Γ

3,10-Dihydroxy-decanoic acid, isolated from royal jelly, stimulates Th1 polarising capability of human monocyte-derived dendritic cells

2011 ◽  
Vol 126 (3) ◽  
pp. 1211-1217 ◽  
Author(s):  
Tanja Dzopalic ◽  
Dragana Vucevic ◽  
Sergej Tomic ◽  
Jelena Djokic ◽  
Ioanna Chinou ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Royal Jelly ◽  
Human Monocyte ◽  
Decanoic Acid

scholarly journals Costimulation of Dectin-1 and DC-SIGN Triggers the Arachidonic Acid Cascade in Human Monocyte-Derived Dendritic Cells

2008 ◽  
Vol 180 (8) ◽  
pp. 5727-5736 ◽  
Author(s):  
Isela Valera ◽  
Nieves Fernández ◽  
Antonio García Trinidad ◽  
Sara Alonso ◽  
Gordon D. Brown ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Arachidonic Acid ◽  
Human Monocyte ◽  
Arachidonic Acid Cascade
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