A phase 2, double-blind, multicenter, randomized, placebo-controlled, dose‑ranging study of the efficacy and safety of Astodrimer Gel for the treatment of bacterial vaginosis

Arthur S. Waldbaum; Jane R. Schwebke; Jeremy R. A. Paull; Clare F. Price; Stephanie R. Edmondson; Alex Castellarnau; Philip McCloud; George R. Kinghorn

doi:10.1371/journal.pone.0232394

A phase 2, double-blind, multicenter, randomized, placebo-controlled, dose‑ranging study of the efficacy and safety of Astodrimer Gel for the treatment of bacterial vaginosis

PLoS ONE ◽

10.1371/journal.pone.0232394 ◽

2020 ◽

Vol 15 (5) ◽

pp. e0232394 ◽

Cited By ~ 2

Author(s):

Arthur S. Waldbaum ◽

Jane R. Schwebke ◽

Jeremy R. A. Paull ◽

Clare F. Price ◽

Stephanie R. Edmondson ◽

...

Keyword(s):

Bacterial Vaginosis ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Dose Ranging

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Efficacy and safety of s201086/GLPG1972, an ADAMTS-5 inhibitor, in patients with knee osteoarthritis: roccella, a 52-week, randomized, double-blind, dose-ranging phase 2 study

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2021.02.348 ◽

2021 ◽

Vol 29 ◽

pp. S264

Author(s):

T.J. Schnitzer ◽

M. Pueyo ◽

H. Deckx ◽

E. van der Aar ◽

K. Bernard ◽

...

Keyword(s):

Knee Osteoarthritis ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Phase 2 Study ◽

Dose Ranging

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A phase 2, randomized, double-blind, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal candidiasis

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2018.03.001 ◽

2018 ◽

Vol 218 (6) ◽

pp. 624.e1-624.e9 ◽

Cited By ~ 17

Author(s):

Stephen R. Brand ◽

Thorsten P. Degenhardt ◽

Karen Person ◽

Jack D. Sobel ◽

Paul Nyirjesy ◽

...

Keyword(s):

Vulvovaginal Candidiasis ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Recurrent Vulvovaginal Candidiasis ◽

Dose Ranging

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Re: Combination Treatment with Mirabegron and Solifenacin in Patients with Overactive Bladder: Efficacy and Safety Results from a Randomised, Double-blind, Dose-ranging, Phase 2 Study (Symphony)

European Urology ◽

10.1016/j.eururo.2015.02.017 ◽

2015 ◽

Vol 67 (6) ◽

pp. 1189-1190

Author(s):

Francisco Cruz

Keyword(s):

Overactive Bladder ◽

Combination Treatment ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Phase 2 Study ◽

Dose Ranging

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Mo1053 A Phase 2, Randomized, Double-Blind, Parallel-Group, Multicenter, Dose-Ranging Study to Evaluate the Efficacy and Safety of a Novel Potassium-Competitive Acid Blocker (P-CAB) TAK-438 in Patients With Erosive Esophagitis

Gastroenterology ◽

10.1016/s0016-5085(13)62088-0 ◽

2013 ◽

Vol 144 (5) ◽

pp. S-564-S-565 ◽

Cited By ~ 2

Author(s):

Tsutomu Chiba ◽

Yuuichi Sakurai ◽

Akira Nishimura ◽

Naoki Hiramatsu ◽

Eiji Umegaki ◽

...

Keyword(s):

Erosive Esophagitis ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Parallel Group ◽

Dose Ranging

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Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial

The Lancet ◽

10.1016/s0140-6736(18)31773-2 ◽

2018 ◽

Vol 392 (10148) ◽

pp. 637-649 ◽

Cited By ~ 128

Author(s):

Patrick M O'Neil ◽

Andreas L Birkenfeld ◽

Barbara McGowan ◽

Ofri Mosenzon ◽

Sue D Pedersen ◽

...

Keyword(s):

Weight Loss ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Trial ◽

Dose Ranging

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Faculty Opinions recommendation of Combination treatment with mirabegron and solifenacin in patients with overactive bladder: efficacy and safety results from a randomised, double-blind, dose-ranging, phase 2 study (Symphony).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718339612.793493406 ◽

2014 ◽

Author(s):

Piotr Radziszewski ◽

Slawomir Poletajew

Keyword(s):

Overactive Bladder ◽

Combination Treatment ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Phase 2 Study ◽

Dose Ranging

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Prospective, randomized, double-blind, Phase 2 dose-ranging study comparing efficacy and safety of imipenem/cilastatin plus relebactam with imipenem/cilastatin alone in patients with complicated urinary tract infections

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/dkx139 ◽

2017 ◽

Vol 72 (9) ◽

pp. 2616-2626 ◽

Cited By ~ 64

Author(s):

Matthew Sims ◽

Valeri Mariyanovski ◽

Patrick McLeroth ◽

Wayne Akers ◽

Yu-Chieh Lee ◽

...

Keyword(s):

Urinary Tract ◽

Urinary Tract Infections ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Dose Ranging ◽

Tract Infections

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Methodology of a phase 2, randomized, double-blind, placebo-controlled, parallel group, dose-ranging, 36-week, multicenter trial to evaluate the efficacy and safety of daxibotulinumtoxinA for injection for the treatment of upper limb spasticity in adults after stroke or traumatic brain injury

Toxicon ◽

10.1016/j.toxicon.2018.11.202 ◽

2018 ◽

Vol 156 ◽

pp. S83

Author(s):

Michael Munin ◽

Atul T. Patel ◽

Allison Brashear ◽

David Simpson ◽

David Charles ◽

...

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Multicenter Trial ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group ◽

Limb Spasticity ◽

Dose Ranging

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Results from a phase 2, randomized, double-blind, placebo-controlled, dose ranging study to evaluate the efficacy and safety of VT 1161 oral tablets in the treatment of patients with recurrent vulvovaginal candidiasis

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2017.08.084 ◽

2017 ◽

Vol 217 (6) ◽

pp. 715 ◽

Cited By ~ 2

Author(s):

J.D. Sobel ◽

S.R. Brand ◽

T.P. Degenhardt ◽

K. Person ◽

P. Nyirjesy ◽

...

Keyword(s):

Vulvovaginal Candidiasis ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Recurrent Vulvovaginal Candidiasis ◽

Dose Ranging

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Faculty Opinions recommendation of Combination treatment with mirabegron and solifenacin in patients with overactive bladder: efficacy and safety results from a randomised, double-blind, dose-ranging, phase 2 study (Symphony).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718339612.793540483 ◽

2017 ◽

Author(s):

Lori Ann Birder

Keyword(s):

Overactive Bladder ◽

Combination Treatment ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Phase 2 Study ◽

Dose Ranging

Download Full-text