scholarly journals Profile of Medicaid enrollees with sickle cell disease: A high need, high cost population

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0257796
Author(s):  
April Grady ◽  
Anthony Fiori ◽  
Dhaval Patel ◽  
Jessica Nysenbaum

Sickle cell disease is a progressively debilitating genetic condition that affects red blood cells and can result in a variety of serious medical complications, reduced life expectancy, and diminished quality of life. Medicaid nationwide covered 66 percent of sickle cell disease hospitalizations in 2004 and 58 percent of emergency department visits for the disease between 1999 and 2007. Using Medicaid data from four states with large populations that account for more than one-third of Medicaid program enrollment, we examined the characteristics of those with sickle cell disease. We found instances of mortality rates more than nine times the age-adjusted population average (in Texas, a mortality rate for Medicaid enrollees with SCD of 1.11 percent compared to 0.12 percent overall); rates of disability-related eligibility–which is associated with long-term Medicaid enrollment–of up to 69 percent; and half or more of affected enrollees having (all-cause) hospital stays, emergency department visits, and opioid prescription fills. With gene therapies on the horizon that will spur discussions of treatment coverage, costs, and outcomes for people with sickle cell disease, it is important for relevant stakeholders to understand the affected populations.

2010 ◽  
Vol 38 (4) ◽  
pp. S536-S541 ◽  
Author(s):  
Hussain R. Yusuf ◽  
Hani K. Atrash ◽  
Scott D. Grosse ◽  
Christopher S. Parker ◽  
Althea M. Grant

2020 ◽  
Vol 184 ◽  
pp. 109292 ◽  
Author(s):  
Amelia H. Blumberg ◽  
Stefanie T. Ebelt ◽  
Donghai Liang ◽  
Claudia R. Morris ◽  
Jeremy A. Sarnat

2017 ◽  
Vol 65 (4) ◽  
pp. e26906 ◽  
Author(s):  
Andrea K. Morrison ◽  
Matthew P. Myrvik ◽  
David C. Brousseau ◽  
Amy L. Drendel ◽  
J. Paul Scott ◽  
...  

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 4610-4610
Author(s):  
Andrea P Borns ◽  
Kristy Marquez ◽  
Djesika Amendah ◽  
Alan Whiteman ◽  
Lanetta B Jordan ◽  
...  

Abstract Abstract 4610 OBJECTIVES Both asthma and sickle cell disease are major Public Health concerns. Previous studies have demonstrated that asthma among children with sickle cell disease (SCD) may increase the risk of developing acute chest syndrome (ACS), which can be life threatening. These respiratory complications may increase emergency department (ED) utilization, increase health care costs, and reduce life span among persons with SCD. The purpose of this study is to determine whether children with SCD and asthma have significantly more ED visits and if they are at higher risk of developing ACS compared to children with SCD who do not have asthma. METHODS We used MarketScan® Multi-State Medicaid Databases from Thompson Reuters (Ann Arbor, Michigan) for the years 2001 to 2005. These are proprietary datasets covering eight unidentified states. We used International Classification of Disease, 9th Division, Clinical Modifications (ICD-9-CM) codes to identify SCD, asthma and ACS. RESULTS In 2005, there were 2428 children with SCD continuously enrolled in Medicaid. Among those, 369 (15.2%) patients were identified as having asthma. The mean number of emergency department visits was significantly higher among children with both SCD and asthma compared to children with SCD without asthma (p<0.05). In addition, children with SCD and asthma were more likely to have at least one episode of ACS than children with SCD without asthma (28.2% vs. 7.8%, respectively). CONCLUSIONS Among children with SCD who are enrolled in Medicaid, asthma is a common comorbidity, which is associated with high incidence of ACS. Therefore asthma should be aggressively managed among SCD patients. Proper management of asthma may result not only in reduced pulmonary complications, but also reduced costs related to emergency department utilization and progression of lung disease into adulthood. Disclosures: No relevant conflicts of interest to declare.


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