scholarly journals Correction: Immunological detection of pyrazine-2-carboxylic acid for the detection of pyrazinamide resistance in Mycobacterium tuberculosis

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0259439
Author(s):  
Edgar A. Florentini ◽  
Noelia Angulo ◽  
Robert H. Gilman ◽  
Roberto Alcántara ◽  
Elisa Roncal ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Carboxylic Acid ◽  
Immunological Detection

scholarly journals Subdivision of Mycobacterium tuberculosis into five variants for epidemiological purposes: methods and nomenclature

1982 ◽  
Vol 89 (2) ◽  
pp. 235-242 ◽  
Author(s):  
C. H. Collins ◽  
M. D. Yates ◽  
J. M. Grange
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Carboxylic Acid ◽  
Nitrate Reductase ◽  
Nitrate Reductase Activity ◽  
Reductase Activity ◽  
Acid Hydrazide ◽  
Epidemiological Studies ◽  
Oxygen Requirement ◽  
Carboxylic Acid Hydrazide ◽  
Virulent Strains

SUMMARYVirulent strains of Mycobacterium tuberculosis isolated from humans are divisible into five variants by using four tests: oxygen requirement (aerobic or microaerophilic), nitrate reductase activity, susceptibility to pyrazinamide (60 μg/ml) and susceptibility to thiophene-2-carboxylic acid hydrazide (5 μg/ml). The five variants are referred to as Classical human, Asian human, bovine, African I and African II. The relation of these variants to previously described types is discussed. This simple division has been shown to be useful in epidemiological studies.

scholarly journals Subdivision ofMycobacterium tuberculosisfor epidemiological purposes: a seven year study of the ‘Classical’ and ‘Asian’ types of the human tubercle bacillus in South-East England

1985 ◽  
Vol 94 (1) ◽  
pp. 9-21 ◽  
Author(s):  
J. M. Grange ◽  
M. D. Yates ◽  
C. H. Collins
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Carboxylic Acid ◽  
Age Distribution ◽  
Acid Hydrazide ◽  
Tubercle Bacillus ◽  
Isolation Rate ◽  
Host Pathogen Interaction ◽  
Asian Patients ◽  
Carboxylic Acid Hydrazide ◽  
South East England

SUMMARYHuman strains ofMycobacterium tuberculosiswere divided into the ‘Classical’ and ‘Asian’ types according to their sensitivity to thiophen-2-carboxylic acid hydrazide. The isolation of these two types in South-East England was studied during a seven-year period (1977–1983). The ‘Asian’ type was more prevalent among ethnic Asian patients than among ethnic Europeans. Among Europeans there was a decline in the isolation rate of ‘Classical’ strains and a small but significant increase in ‘Asian’ strains during the study period, so that the proportion of the latter type in this group is increasing. The type of bacillus was unrelated to the site of isolation except that the incidence of lymphadenitis due to the ‘Asian’ type among European females was significantly higher than expected. In general, European patients tended to be older than Asian patients, and the differences in age distribution according to site of isolation and type of bacillus in each ethnic group were small. A notable exception occurred with European females infected with the ‘Asian’ type, whose age distribution was similar to the Asians.In view of the differences in behaviour of the two types of human tubercle bacilli in this country there is a need to cintinue a bacteriological surveillance and also to determine whether the nature of the host–pathogen interaction varies according to the type of bacillus.

scholarly journals Activity of Thiazole-carboxylic Acid Hydrazides on Mycobacterium tuberculosis

1953 ◽  
Vol 73 (2) ◽  
pp. 126-127 ◽  
Author(s):  
Yoshiyuki Takata ◽  
Ken-ichi Yamamoto ◽  
Yoshihiro Takata
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Carboxylic Acid
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