scholarly journals Association between the seminal vesicle weight and certain steroids in buffaloes (Bubalus bubalis)

2014 ◽  
Vol 7 (1) ◽  
pp. 21-25 ◽  
Author(s):  
S. Shinde ◽  
S. Mahmood ◽  
G. Singh ◽  
M. R. Verma
Keyword(s):  
Seminal Vesicle ◽  
Bubalus Bubalis ◽  
Seminal Vesicle Weight

Infrastructure and Innervation of Water Buffalo (Bubalus bubalis) Seminal Vesicle

1992 ◽  
Vol 145 (4) ◽  
pp. 420-429 ◽  
Author(s):  
A. Abou-Elmagd ◽  
R. Kujat ◽  
K.-H. Wrobel
Keyword(s):  
Seminal Vesicle ◽  
Water Buffalo ◽  
Bubalus Bubalis

Effects of prenatal X-irradiation on testicular function and morphology in the rat

1959 ◽  
Vol 196 (4) ◽  
pp. 896-898 ◽  
Author(s):  
Benjamin H. Ershoff
Keyword(s):  
Seminal Vesicle ◽  
Prenatal Development ◽  
Male Rat ◽  
Testicular Function ◽  
Seminal Vesicle Weight ◽  
X Irradiation ◽  
Testicular Injury

Present findings confirm and extend previous observations that x-irradiation during certain stages of prenatal development results in testicular injury and infertility in the male rat. The effects were particularly marked in the offspring of rats irradiated on the 18th day of pregnancy. These rats also showed in addition to testes injury a significant reduction in seminal vesicle weight. Testicular injury also occurred in the offspring of rats irradiated on the 14th day of pregnancy but was less marked than in the 18-day series. No abnormalities in testicular function or morphology were observed in the offspring of rats irradiated on the 10th day of pregnancy.

THE COMPARATIVE ACTIONS OF TESTOSTERONE PROPIONATE AND 5α-ANDROSTAN17β-OL-3-ONE PROPIONATE ON THE REPRODUCTIVE BEHAVIOUR, PHYSIOLOGY AND MORPHOLOGY OF MALE RATS

1971 ◽  
Vol 51 (2) ◽  
pp. 241-NP ◽  
Author(s):  
H. H. FEDER
Keyword(s):  
Body Weight ◽  
Seminal Vesicle ◽  
Sexual Behaviour ◽  
Testosterone Propionate ◽  
Reproductive Behaviour ◽  
Male Rats ◽  
Male Sexual Behaviour ◽  
Testicular Weight ◽  
Seminal Vesicle Weight ◽  
Experienced Adult

SUMMARY 5α-Androstan-17β-ol-3-one in its free or in its propionate form was injected systemically (125 μg/day/rat) into sexually experienced, adult, castrated, male rats. These compounds were ineffective in activating masculine behaviour patterns, despite having measurable effects on body weight, seminal vesicle weight and penile morphology. The propionate form also had strong anti-gonadotrophic properties, since when it was injected for 6 days into intact, immature, male rats it significantly reduced testicular weight. In contrast, testosterone propionate (125 μg/day/rat) restored male sexual behaviour to the levels found before castration when injected systemically. Testosterone propionate also affected body weight, seminal vesicle weight, penile morphology and the testicular weight of immature males. These effects may have been due in part to conversion of testosterone to 5α-androstan-17β-ol-3-one, but this metabolic step does not seem to be obligatory for activation of male sexual behaviour in rats.

scholarly journals Variability of response in cross-fostered rats

1972 ◽  
Vol 6 (2) ◽  
pp. 225-234 ◽  
Author(s):  
R. M. Sharpe ◽  
Audrey Morris ◽  
A. C. Wyatt ◽  
P. S. Brown
Keyword(s):  
Seminal Vesicle ◽  
Ovarian Response ◽  
Time Variability ◽  
Sleeping Time ◽  
Immature Rats ◽  
Seminal Vesicle Weight ◽  
The Cross

The variability of the response to drugs of immature rats bred in natural litters was compared with that of rats cross-fostered into all-male or all-female groups of 9, 12 and 14. The variability of ovarian response to gonadotrophin was significantly greater in naturally-bred animals than in those from cross-fostered litters. There was a suggestion of a similar effect in the variability of barbiturate sleeping time. Variability of seminal vesicle weight, used as an index of response to gonadotrophin in males, did not differ significantly between the cross-fostered and natural litters. Unexpectedly, cross-fostered rats gained more weight in the 4 days after weaning than naturally-bred rats.

INFLUENCE OF VARIOUS STEROIDS ON TESTES AND ACCESSORY SEX ORGANS IN THE RAT

1965 ◽  
Vol 49 (1) ◽  
pp. 145-154 ◽  
Author(s):  
Fred A. Kind ◽  
M. Maqueo ◽  
Ralph I. Dorfman
Keyword(s):  
Seminal Vesicle ◽  
Treatment Period ◽  
Post Treatment ◽  
Testicular Atrophy ◽  
Male Rats ◽  
Ventral Prostate ◽  
Testis Weight ◽  
Intact Male ◽  
Seminal Vesicle Weight ◽  
Testicular Histology

ABSTRACT Various neutral steroids were studied in intact male rats for their ability to influence testicular function, particularly spermatogenesis. The compounds were injected once daily for 21 days, starting at 21 days of age. One day after the last injection, testicular histology and testis, ventral prostate, and seminal vesicle weights were determined. In some experiments, after the standard 21 day treatment period, testicular histology and function were evaluated after 30 and 60 day post-treatment recovery periods. 2α-Hydroxymethyl-17β-hydroxy-5α-androstan-3-one, 2-hydroxy-5α-androst-2-en-17β-ol, 2,17α-dimethyl-5α-androst-2-en-17β-ol and 2-formyl5α-androst-2-en-17β-ol caused decreases in testicular, ventral prostate and seminal vesicle weight and produced arrest of spermatogenesis. These effects were reversible and testis weight and histology, as well as fertility, were restored in the post-treatment period. 19-Norprogesterone, which did not produce convincing testicular atrophy, did cause significant decreases in ventral prostate and seminal vesicle weight. Chlormadinone showed a similar picture, although direct antagonistic testicular effects were also seen. The lowered ventral prostate and seminal vesicle weights produced by these compounds may be an expression of their antiandrogenic activity.

scholarly journals Curcumin ameliorates atrophy of seminal vesicle via reduction of oxidative stress in castrated mice

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7192 ◽  
Author(s):  
Rui Li ◽  
Hao Li ◽  
Ke Rao ◽  
Kang Liu ◽  
Yan Zhang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Body Weight ◽  
Seminal Vesicle ◽  
Serum Testosterone ◽  
The Body ◽  
Intragastric Administration ◽  
Curcumin Treatment ◽  
Seminal Vesicle Weight ◽  
High Level ◽  
And Function

Background The growth and function of seminal vesicle are dependent on androgen. This study was conducted to investigate the role of oxidative stress in castration-induced seminal vesicle atrophy and to explore the effects of curcumin, an antioxidant extracted from rhizome of turmeric, on seminal vesicle of castrated mice. Methods C57BL/6J mice were randomly divided into three groups: control, castration, and castration with curcumin (n = 10 for each group). After surgical castration, mice in the curcumin treatment group received intragastric administration of curcumin at 100 mg/kg body weight for 4 weeks, whereas mice in the other two groups were treated with olive oil. After that, the body weight, seminal vesicle weight and serum testosterone of mice were measured. Apoptosis and oxidative stress levels in seminal vesicle were also determined. Results After castration, both the weight and size of seminal vesicle decreased dramatically. The expression of three NADPH oxidase (NOX) subtypes: NOX1, NOX2 and NOX4, increased in seminal vesicle of castrated mice, resulting in high level oxidative stress. The ratio of Bax to Bcl-2 was also elevated after castration, accompanied by enhanced caspase3 activity. Additionally, castration increased the number of apoptotic cells in seminal vesicle. Curcumin treatment could inhibit the expression of NOX1, NOX2 and NOX4, decreasing oxidative stress and apoptosis. The atrophy of seminal vesicle caused by castration was ameliorated by curcumin. Conclusion Castration could cause atrophy of seminal vesicle probably via inducing oxidative stress. Curcumin treatment could reduce the oxidative stress in seminal vesicle by decreasing the expression of NOX1, NOX2 and NOX4, thereby ameliorating apoptosis and atrophy of seminal vesicle. Oxidative stress might play a role in castration-induced seminal vesicle atrophy.

EFFECTS OF HUMAN MENOPAUSAL GONADOTROPHIN PREPARATIONS IN DIFFERENT BIOASSAY METHODS

1964 ◽  
Vol 47 (3) ◽  
pp. 409-418 ◽  
Author(s):  
H. van Hell ◽  
R. Matthijsen ◽  
G. A. Overbeek
Keyword(s):  
Seminal Vesicle ◽  
Test Methods ◽  
Starch Gel Electrophoresis ◽  
Uterine Weight ◽  
Human Pituitary ◽  
Human Menopausal Gonadotrophin ◽  
Seminal Vesicle Weight ◽  
Starch Gel ◽  
Weight Test ◽  
Weight Method

ABSTRACT Several gonadotrophin preparations, HMG (Human Menopausal Gonadotrophin), HPG (Human Pituitary Gonadotrophin) and NIH FSH S1 (a FSH preparation distributed by the National Institute of Health) were investigated for biological activity, using three methods of assay. The rat augmentation test, specific for FSH, and the rat seminal vesicle weight test, specific for ICSH both gave statistically valid results. The potencies were expressed in terms of the IRP (International Reference Preparation for HMG), and the International HCG Standard respectively. The gonadotrophic activity as determined by the rat uterine weight method was expressed in terms of IRP and in terms of the International HCG Standard. Good agreement was found between the results in the uterine weight method and the seminal vesicle test, suggesting a strong ICSH dependence for the former. On the other hand, the results of the uterine weight method and the augmentation test were not in agreement. Consequently the rat uterine weight method must be regarded as completely unsuitable for the assay of FSH-activity. Among the three test methods studied, the augmentation test appears to be the only one suitable for the assay of the FSH content of gonadotrophin preparations for clinical use. Fractionation of HMG with ethanol led to preparations with high FSH activity, 200 to 300 times that of IRP, but with little ICSH activity. Most of the ICSH was concentrated in other fractions, indicating that both hormones can be separated. In starch gel electrophoresis these fractions showed different patterns.

A COMPARISON OF SEMINAL VESICLE, KIDNEY AND ADRENAL RESPONSES IN THE RAT FOLLOWING THE ADMINISTRATION OF ANDROGEN

1960 ◽  
Vol XXXIV (III) ◽  
pp. 344-352 ◽  
Author(s):  
Jerome A. Grunt ◽  
Joseph E. Walker
Keyword(s):  
Seminal Vesicle ◽  
Histological Examination ◽  
Testosterone Propionate ◽  
Seminal Vesicles ◽  
Sesame Oil ◽  
Male Rats ◽  
Subcutaneous Injections ◽  
Sexual Organ ◽  
Seminal Vesicle Weight

ABSTRACT The responses of several seminal vesicle in vivo microscopic characteristics, seminal vesicle contractions, seminal vesicle, kidney and adrenal weights and seminal vesicle histology have been compared following the administration of testosterone propionate (T. P.) and norethandrolone (19-NT) to castrated male rats. Fourteen days after castration 35 male Osborne-Mendel rats were divided into 5 groups each containing 6 to 8 animals and given daily subcutaneous injections of 0.1 ml sesame oil with or without added steroids. The groups were: I – sesame oil; II – 100 μg 19-NT; III – 500 μg 19-NT; IV – 100 μg T.P.; V – 500 μg T. P. After 7 days of injections, seminal vesicles were studied by the transillumination method of Knisely. The seminal vesicles, adrenals and kidneys were then removed and weighed and the vesicles were prepared for routine histological examination. The adrenal and kidney weights, as well as the seminal vesicle contractions, responded to both steroids in a similar manner, however, seminal vesicle weight and histology and in vivo characteristics differed greatly. 19-NT appeared to have very little effect on vesicle weight, in vivo characteristics and histology although contractions were inhibited in 13 of 14 animals so treated. Therefore, when used as the end-point in hormonal reactions, seminal vesicle contractions should not be considered comparable to the usual secondary sexual organ reactivity to hormones.

Leydig cell resistance to the cytotoxic effect of ethylene dimethanesulphonate in the adult rat testis

1985 ◽  
Vol 105 (3) ◽  
pp. 311-NP ◽  
Author(s):  
I. D. Morris
Keyword(s):  
Seminal Vesicle ◽  
Leydig Cell ◽  
Leydig Cells ◽  
Serum Testosterone ◽  
Male Rats ◽  
Cell Physiology ◽  
Testis Weight ◽  
Endocrine Activity ◽  
Adult Rat ◽  
Seminal Vesicle Weight

ABSTRACT Weekly doses of the Leydig cell cytotoxic ethylene dimethanesulphonate (EDS) were administered to adult male rats in an attempt to study the endocrine activity of the testis in the absence of Leydig cells. One week after the first dose serum testosterone and LH concentrations and seminal vesicle weights were close to levels in castrated rats and testicular human chorionic gonadotrophin (hCG) binding was severely depressed. These changes were maintained for a further week but subsequently began to return to, but did not achieve, control levels. After six weekly doses seminal vesicle weight and serum testosterone concentrations were significantly higher than in the castrated rats. Serum LH concentrations were declining towards control values at 4 weeks but had risen again at 6 weeks. Serum FSH concentrations were raised to about 50% of the value in castrated rats throughout the period studied. Testis weight and hCG binding, which initially fell, were partially restored at 6 weeks and spermatogenesis was recovering. The data show that responses of the testis to multiple doses of EDS are similar to those after a single dose. This apparent resistance indicates that the regenerating Leydig cells are functionally different from the mature Leydig cell. The similarities between the maturing Leydig cell seen after EDS destruction and those in the immature rat suggest that EDS will provide a valuable model for the investigation of Leydig cell physiology. J. Endocr. (1985) 105, 311–316

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