scholarly journals Book Review: “In Vitro Drug Release Testing of Special Dosage Forms,” Advances in Pharmaceutical Technology Series, Edited by Fotaki and Klein

2021 ◽  
Vol 28 (2) ◽  
pp. 42-42
Author(s):  
Greg Martin
Keyword(s):  
Drug Release ◽  
Dosage Forms ◽  
In Vitro Drug Release ◽  
Pharmaceutical Technology ◽  
Release Testing

In vitro drug release testing of controlled release veterinary drug products

2000 ◽  
pp. 311-332 ◽  
Author(s):  
Michael J. Rathbone ◽  
Jingjian Shen ◽  
Colin R. Ogle ◽  
Shane Burggraaf ◽  
Craig R. Bunt
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Veterinary Drug ◽  
In Vitro Drug Release ◽  
Drug Products ◽  
Release Testing

Synthesis of antibiotic-loaded interporous hydroxyapatite blocks by vacuum method and in vitro drug release testing

Biomaterials ◽  
1998 ◽  
Vol 19 (7-9) ◽  
pp. 817-819 ◽  
Author(s):  
Mansho Itokazu ◽  
Wenyi Yang ◽  
Takaaki Aoki ◽  
Akira Ohara ◽  
Naoki Kato
Keyword(s):  
Drug Release ◽  
In Vitro Drug Release ◽  
Vacuum Method ◽  
Release Testing

scholarly journals Formulation and evaluation of different topical dosage forms for wound healing properties

2020 ◽  
Vol 11 (1) ◽  
pp. 730-746
Author(s):  
Dandasi Jayachandra Dev ◽  
Jayaprakash J S ◽  
Kulkarni P K ◽  
Akhila A R ◽  
Namratha S Saraf
Keyword(s):  
Particle Size ◽  
Wound Healing ◽  
Drug Release ◽  
Dosage Forms ◽  
Cyclodextrin Complexes ◽  
In Vitro Drug Release ◽  
Topical Dosage ◽  
Topical Dosage Forms ◽  
Wound Healing Activity

The aim of the present work was to compare the wound healing efficacy of different topical dosage forms such as β cyclodextrin complex gel, liposomal gel, and ointment on the rat model. Simvastatin was used as a drug, β cyclodextrin was used as a complexing agent to enhance solubility, L α Phosphatidylcholine as a phospholipid, and cholesterol as a stabilizing agent. Liposomes were prepared by thin-film hydration method, β cyclodextrin complexes of simvastatin were prepared by spray drying technique, and the ointment was prepared in simple method. Beta cyclodextrin gels and liposomal gels were prepared by direct incorporation of spray-dried products and lyophilized liposomes into Carbopol gel. The gel was evaluated for drug content, particle size, viscosity, spreadability, surface morphology, in-vitro drug release studies, skin irritation study, and wound healing activity studies. FTIR and DSC studies showed no chemical interaction between the drug and excipients. The particle size of β cyclodextrin complexes was in the range of 0.5 μm to 2.5 μm and for liposomes 163 nm to 725 nm. The in-vitro drug release was 96.7 % at the end of the sixth hour for β cyclodextrin gel, 29.7 % at the end of the sixth hour for liposomal gel, and 96.2 % at the end of 3 hours for ointment. Wound healing activity studies were carried out for 21 days on albino wrister rats, a period of epithelization, and rate of wound contraction was measured on 4, 8, 14, 16, and 21 days. Simvastatin ointment showed a significant effect on wound healing in the rat model compared to β-cyclodextrin gel and liposomal gel. Hence, Simvastatin ointment could be a potential dosage form for clinical utility on wound healing.

Investigating in Vitro Drug Release Mechanisms Inside Dosage Forms

1997 ◽  
pp. 129-135 ◽  
Author(s):  
C. D. Melia ◽  
P. Marshall ◽  
P. Stark ◽  
S. Cunningham ◽  
A. Kinahan ◽  
...  
Keyword(s):  
Drug Release ◽  
Dosage Forms ◽  
In Vitro Drug Release ◽  
Release Mechanisms
Sign in / Sign up

Export Citation Format

Share Document