scholarly journals Bone mineral density and mandibular osteoporotic alterations in type 2 diabetes

2018 ◽  
Vol 21 (2) ◽  
pp. 220
Author(s):  
Luciana Munhoz ◽  
Isabela Goulart Gil Choi ◽  
Reinaldo Abdala Junior ◽  
Rogério Abdala ◽  
Emiko Saito Arita

<p><strong>Objective</strong><strong>:</strong> To assess the influence of type 2 diabetes on bone mineral density in a group of type 2 diabetic patients, in comparison with non-diabetic patients. Additionally, to evaluate the correlation between mandibular cortical index and bone mineral density. <strong>Material and Methods: </strong>48 patients (24 diabetics and 24 non-diabetics) referred for femur and spine densitometry and panoramic radiograph examination were included in this study. Patients were diagnosed based on densitometric results of the total femur and total spine. All panoramic radiomorphometric measurements were performed by 3 observers. Differences in T and Z-scores between both groups were evaluated with Mann-Whitney test and non-parametric correlations between mandibular cortical index and T/Z-scores were carried out with Spearman’s test. <strong>Results</strong>: Median T and Z-scores for total femur and total spine presented no statistical significant difference between diabetic and non-diabetic patients. In addition, only diabetics total femur and non-diabetics total spine T-scores were significantly correlated with mandibular cortical index. <strong>Conclusion:</strong> The present results suggest that type 2 diabetic patients have similar Z and T-scores in femur and spine when compared to non-diabetic patients. Mandibular cortical index, assessed on panoramic radiographs is inversely correlated with femur densitometry results in diabetics and spine bone mineral density in non-diabetic patients.</p><p> </p><p><strong>Keywords</strong></p><p>Bone Mineral Density; Dual X-Ray Absorptiometry; Panoramic radiography; Osteoporosis; Type 2 Diabetes.</p>

Bone ◽  
2010 ◽  
Vol 47 ◽  
pp. S185
Author(s):  
A. Shepelkevich ◽  
N. Vasilieva ◽  
O. Baranova ◽  
E. Reunova

2018 ◽  
Vol 17 ◽  
pp. e181211
Author(s):  
Wladimir Gushiken de Campos ◽  
Gonzalo André Montesinos ◽  
Rosa Cristina Peinado Agudo ◽  
Kaisermann Costa ◽  
Luciana Munhoz ◽  
...  

Aim: This study aim was to evaluate if patients with type 2 diabetes and osteoporosis have an increased risk of periodontal disease (horizontal and vertical bone loss) when compared to diabetic patients without osteoporosis. Additionally, to assess if patients with diabetes and osteoporosis have a greater risk of reduction of bone mineral density in the mandible, expressed by mandibular cortical index (MCI) when compared to diabetic patients without osteoporosis. Methods: 59 patients (39 diagnosed with type 2 diabetes and osteoporosis; 20 diagnosed with type 2 diabetes and without osteoporosis) were selected. Type 2 diabetes was previously diagnosed by glycated hemoglobin examination and osteoporosis by peripheral dual-energy x-ray absorptiometry. Mandibular cortical index, as well as the presence of vertical and horizontal bone loss was verified on panoramic radiographs. Adjusted odds ratio analyses were performed on presence of periodontal disease and MCI considering the effect of osteoporosis. Results: Absence of statistical significance between variables was found. Conclusions: There is no difference between the risk of periodontal disease or low MCI among osteoporotic and non-osteoporotic type 2 diabetic patients.


2018 ◽  
Vol 51 (01) ◽  
pp. 42-46
Author(s):  
Hae Lee ◽  
Jong Yoon ◽  
Kyu Park ◽  
Jung Lim ◽  
Jin Hwang

AbstractLong-term effects of type 2 diabetes mellitus (T2D) on bone health remain unclear. The objective of this study was to assess the possible association of bone mineral density (BMD) at multiple sites with T2D after correcting for several potential confounders such as age, sex, Tanner stage, and BMI known to affect BMD in adolescents with newly developed T2D. In this cross-sectional study, 17 children and adolescents with T2D and 59 age, sex, and BMI-matched controls were included. All subjects underwent dual-energy X-ray absorptiometry to measure regional and whole-body composition with Lunar Prodigy at the time of initial diagnosis. A BMD Z-score was calculated using data from healthy Korean children and adolescents after adjusting for height-for-age. The mean age of all subjects was 12.9±2.4 years (range, 8.3–18.3 years). BMDht Z-scores for lumbar spine and total body after adjusted for age, sex, BMI SDS, and Tanner stage were not significantly different between patients and controls. However, BMDht Z-scores for femur neck and bone mineral apparent density (BMAD) Z-scores of lumbar spine were significantly lower in T2D patients than those in healthy controls. HOMA-IR or HbA1c was not associated with BMDht Z-scores at multiple sites. BMDht Z-scores at multiple sites except femur neck in adolescents with newly developed T2D were similar to those in obese controls after adjustment for potential confounders.


Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S395
Author(s):  
A.P. Shepelkevich ◽  
E.G. Reunova ◽  
E.V. Rudenko ◽  
N.A. Vasilieva ◽  
O.V. Baranova

2020 ◽  
Vol 7 (9) ◽  
pp. 1380
Author(s):  
Ningthoukhongjam Reema ◽  
Jyoti Jain ◽  
Thangjam Gautam Singh ◽  
Shashank Banait

Background: Diabetes mellitus is fast becoming the epidemic of the 21st century. It is a metabolic disease that affects multiple organ system in the body including bone metabolism and bone mass. There is high prevalence of decreased bone mineral density (BMD) in type 2 diabetes mellitus (T2DM) patients leading to osteoporosis, osteopenia and fracture. The aim of the present study was to find the magnitude and correlates of altered BMD in T2DM patients of central rural India.Methods: This cross-sectional study was carried out at a tertiary care teaching hospital in central rural India from 2014 to 2016. It comprises of 200 T2DM patients with aged ≥35 years. Bone mineral density measurements were done by using peripheral dual energy X-ray absorptiometry (DEXA).Results: Mean age of study subjects was 56.13±11.12 years with 43.5% males and 56.5% females. Our study results showed the magnitude of decreased BMD was 82%. 53% of the study subjects were osteoporotic and 29% were osteopenic. Significant associations were detected between decreased BMD and old age, female gender, high body mass index, high fasting blood sugar, high HbA1c and low serum calcium on multivariate analysis.Conclusions: The prevalence of decreased BMD in patients with T2DM of central rural India is high, especially in females’ patients, obese patients, and uncontrolled diabetic patients. Awareness amongst the health care provider of this changes will directly affect the treatment decisions for patients, thereby preventing osteoporosis, osteopenia and mitigating potential fracture risk.


2001 ◽  
Vol 44 (4) ◽  
pp. 141-143 ◽  
Author(s):  
Günşah Şahin ◽  
Selda Bağis ◽  
Özlem Bölgen Cimen ◽  
Sacettin Özişik ◽  
Hayal Güler ◽  
...  

The relationship between type 2 diabetes and osteoporosis has not been well established. We studied a population composed of 161 post-menopausal women with type 2 diabetes and a control group. We examined bone mineral density with the dual-energy X-ray absorptiometry(DXA) technique at the lumbar and femoral regions and in a subgroup of patients, we also measured the levels of markers of bone remodelling. We found significantly higher levels of bone mineral density at the lumbar and femoral levels in the diabetic subjects compared with the control group. Moreover, we found higher level of urinary calcium in the controls. On the basis of these results, we suggest that osteoporosis cannot be considered a complication of type 2 diabetes.


Diabetes Care ◽  
2007 ◽  
Vol 30 (7) ◽  
pp. 1860-1861 ◽  
Author(s):  
S. Dhindsa ◽  
V. Bhatia ◽  
G. Dhindsa ◽  
A. Chaudhuri ◽  
G. M. Gollapudi ◽  
...  

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