Transepithelial Brush Biopsies With Computer-Assisted 3-Dimensional Analysis Markedly Improve Detection of Barrettʼs Esophagus and Dysplasia: Interim Analysis From a Prospective Multicenter Community-Based Study

2015 ◽  
Vol 110 ◽  
pp. S728
Author(s):  
Erkanda P. Ikonomi ◽  
Rajiv Bhuta ◽  
Natalya Iorio ◽  
Rahul Kataria ◽  
Vivek Kaul ◽  
...  
Author(s):  
Antonia M. Milroy

In recent years many new techniques and instruments for 3-Dimensional visualization of electron microscopic images have become available. Higher accelerating voltage through thicker sections, photographed at a tilt for stereo viewing, or the use of confocal microscopy, help to analyze biological material without the necessity of serial sectioning. However, when determining the presence of neurotransmitter receptors or biochemical substances present within the nervous system, the need for good serial sectioning (Fig. 1+2) remains. The advent of computer assisted reconstruction and the possibility of feeding information from the specimen viewing chamber directly into a computer via a camera mounted on the electron microscope column, facilitates serial analysis. Detailed information observed at the subcellular level is more precise and extensive and the complexities of interactions within the nervous system can be further elucidated.We emphasize that serial ultra thin sectioning can be performed routinely and consistently in multiple user electron microscopy laboratories. Initial tissue fixation and embedding must be of high quality.


2006 ◽  
Author(s):  
Sergi Gallego ◽  
Manuel F. Ortuño ◽  
Cristian Neipp ◽  
Andrés Márquez ◽  
Augusto Beléndez ◽  
...  

1992 ◽  
Vol 1992 (172) ◽  
pp. 487-499 ◽  
Author(s):  
Mitsuyasu Nagahama ◽  
Shin-ichi Nagahama ◽  
Yukiharu Nekado ◽  
Takae Yamamori ◽  
Tohru Hori

2017 ◽  
Vol 31 (10) ◽  
pp. e340-e346 ◽  
Author(s):  
Do Young Park ◽  
Jae Ho Cho ◽  
Doo-Hyung Lee ◽  
Wan-Sun Choi ◽  
Jun Young Bang ◽  
...  

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