scholarly journals 398 Identification of Varicella Zoster by Novel Salivary and Esophageal Muscle Tissue Assay in Patients With Achalasia: A Two Center Prospective Study

2019 ◽  
Vol 114 (1) ◽  
pp. S233-S233
Author(s):  
Rishi Naik ◽  
Anne Gershon ◽  
Tina Higginbotham ◽  
Michael Gershon ◽  
Jason Chen ◽  
...  
1996 ◽  
Vol 117 (1) ◽  
pp. 165-171 ◽  
Author(s):  
T. G. Wreghitt ◽  
J. Whipp ◽  
C. Redpath ◽  
W. Hollingworth

SummaryThis prospective study analyses infections with varicella-zoster virus (VZV) in Addenbrooke's Hospital, Cambridge during 1987–92 and examines the spread of infection. In total, 93 patients and staff experienced VZV infection. Twenty-one patients had varicella and 49 experienced zoster. None of 101 patients and 1 of 625 staff members in contact with varicella cases acquired infection. By contrast, 2 of 227 patients, and 5 of 1039 staff in contact with zoster cases acquired varicella. One out of 28 (3·6%) VZV antibody-negative patients and staff in contact with varicella acquired infection, compared with 5 out of 29 (17·2%) VZV antibody-negative patients and staff in contact with zoster. Thus, zoster was found to be a more frequent cause of nosocomial infection than varicella. Fourteen members of staff had VZV infection during the study period. One of 99 patients and none of 389 staff members in contact with these cases developed varicella. The cost of dealing with infection control for VZV infections in our hospital is estimated to be £714 per patient case and a total of £13204 per year.


2020 ◽  
Vol 158 (6) ◽  
pp. S-40
Author(s):  
Rishi D. Naik ◽  
Anne Gershon ◽  
Tina Higginbotham ◽  
Jason Chen ◽  
Elizabeth Y. Flores ◽  
...  

2021 ◽  
Author(s):  
Ali Bülent Cengiz ◽  
Ceren Günbey ◽  
Mehmet Ceyhan ◽  
Gülay Korukluoğlu ◽  
Sevgen Tanır Başaranoğlu ◽  
...  

AbstractEncephalitis is a serious neurological syndrome caused by inflammation of the brain. The diagnosis can be challenging and etiology remains unidentified in about half of the pediatric cases. We aimed to investigate demographic, clinical, laboratory, electroencephalographic and neuroimaging findings, and outcome of acute encephalitis of nonbacterial etiology. This prospective study included children hospitalized with the diagnosis of acute encephalitis between 2017 and 2019. Microbiological investigations of the cerebrospinal fluid (CSF) were recorded. All CSF specimens were tested for anti-N methyl D-aspartate receptor (NMDAR) antibodies. In total, 31 children aged 10 months to 17 years (median = 6 years) were included. Pathogens were confirmed in CSF in three patients (9.7%): varicella zoster virus, herpes simplex virus type 1 (HSV-1), and both HSV-1 and NMDAR antibodies. Presenting features included encephalopathy (100%), fever (80.6%), seizure (45.2%), focal neurological signs (29%), and ataxia (19.4%). On clinical follow-up of median 9 (6–24) months, six patients showed neurological deficits: together with two patients who died in hospital, total eight (25.8%) patients were considered to have unfavorable outcome. Need for intubation, receiving immunomodulatory treatment, prolonged hospitalization, and high erythrocyte sedimentation rate at admission were associated with unfavorable outcome. The etiology of encephalitis remains unexplained in the majority of children. HSV-1 is the most frequently detected virus, consistent with the literature. The fact that anti-NMDAR encephalitis was detected in one child suggests autoimmune encephalitis not being rare in our center. The outcome is favorable in the majority while about one-fifth of cases suffer from sequelae.


2020 ◽  
pp. 21-27
Author(s):  
Andreyanov

The spread of alariosis of fishing animals of Central Russia was clarified and a circle of host agents among mammals was identified. The material for the study was the arcasses of trade animals. The period of work was 2018–2020. Animals were studied according to the method of complete helminthological study on K.I. Skryabin (1928). The tissue form of alariosis was examined by trichinelloscopic methods. During the reporting period, 107 heads of carnivorous animals (of which 27 heads (25.2%) are considered stray domestic) extracted in the territory of the Ryazan, Vladimir and Moscow regions. Of the Canidae family, 54 heads have undergone helminthological examination (29 foxes, 17 domestic dogs, 7 raccoon dogs, and 1 wolf). Of the cat (Felidae), 11 heads have been studied (domestic cats – 10, lynx – 1). Martens animals (Mustelinae) have been studied 42 heads (forest мartens – 19, stone мartens – 6, river otter – 4, ermines – 7, badgers – 2, аmerican mink – 4). Adult trematodes have been identified in 37 carnivorous animals (34.6%) in the thin part of the intestine. Canidae animals representing trade species (fox, raccoon dog, wolf) are 100% infected with the agent of alariosis. The intensity invasion of fox was 4–250 copies per head, raccoon dogs – 11–284, wolf – 84. The larval form of the agent was recorded in one fox (3.5%), 2 forest мartens (10.5%) and one аmerican mink (25.0%). Mesocercaries of trematodes were localized in a transparent capsule in lung parenchyma, in diaphragm muscle tissue, in esophageal muscle tissue.


2007 ◽  
Vol 196 (7) ◽  
pp. 1014-1020 ◽  
Author(s):  
N. Sengupta ◽  
Y. Taha ◽  
F. T. Scott ◽  
M. E. Leedham‐Green ◽  
M. Quinlivan ◽  
...  

2013 ◽  
Vol 5 (14) ◽  
pp. 6549-6555 ◽  
Author(s):  
Changfeng Gong ◽  
Lei Hou ◽  
Yabin Zhu ◽  
Jingjing Lv ◽  
Yuxin Liu ◽  
...  

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