scholarly journals Posthuman? Animal Corpses, Aeroplanes and Very High Frequencies in the Work of Valentine Ackland and Sylvia Townsend Warner

Author(s):  
David RM Trotter

The aim of this article is to establish the critical significance and value of work which was the product of the unique creative partnership developed by Valentine Ackland and Sylvia Townsend Warner during the 1930s. During that period, I argue, they imagined more variously and more incisively together, through mutual awareness and acceptance, than they would in all likelihood have done had they never met and fallen in love. An understanding of the sharp differences in temperament, outlook and reputation which precluded full-scale collaboration freed each of them, in turn, to pursue contrasting aspects of concerns held in common. So adventurous was that pursuit, at times, that it merits comparison with recent investigations of the idea of the ‘posthuman’. Since Warner was by far the more prolific author, I have tried to balance my account of her partnership with Ackland by drawing extensively not only on published fiction and poetry, but also on diaries and letters, and on a variety of other kinds of material from the archive.

1930 ◽  
Vol 68 (401) ◽  
pp. 556-559
Author(s):  
C.L. Fortescue ◽  
L.A. Moxon

1984 ◽  
Vol 160 (1) ◽  
pp. 1-11 ◽  
Author(s):  
M Slaoui ◽  
O Leo ◽  
J Marvel ◽  
M Moser ◽  
J Hiernaux ◽  
...  

We have shown that, by suitable idiotypic manipulation, BALB/c mice can express the major cross-reactive idiotype (CRI) of A/J mice in response to azophenylarsonate (Ars). In order to know if the CRIA idiotype is present in the potential repertoire of BALB/c before any intentional selection, we used polyclonal activation in vitro and limiting dilution analysis. The readout was done with two monoclonal anti-CRIA antibodies that recognize distinct idiotopes on a CRIA+ A/J germline-encoded monoclonal antibody. We studied the frequency of CRIA+ lipopolysaccharide (LPS)-reactive cells in the spleens of nonimmune and immune A/J mice and in the spleens of naive and manipulated (i.e., producing CRIA+ antibodies) BALB/c mice. A/J and BALB/c naive individuals presented very high frequencies of Ars-specific B cells while the frequency of CRIA+ B cells was only a minor subset (0.5%) of the total Ars-specific subset in the two strains. When A/J mice were immunized with Ars-keyhole limpet hemocyanin, a clear preferential expansion of the CRIA+ minor subset of A/J mice was observed (100x). No such enhancement was observed in BALB/c mice similarly treated. Manipulated BALB/c mice presented a higher frequency of CRIA+ anti-Ars B cells than naive or antigen-immunized BALB/c individuals.


Genetics ◽  
1998 ◽  
Vol 148 (1) ◽  
pp. 267-275
Author(s):  
Isabelle Busseau ◽  
Sophie Malinsky ◽  
Maria Balakireva ◽  
Marie-Christine Chaboissier ◽  
Danielle Teninges ◽  
...  

Abstract I factors in Drosophila melanogaster are non-LTR retrotransposons similar to mammalian LINEs. They transpose at very high frequencies in the germ line of SF females resulting from crosses between reactive females, devoid of active I factors, and inducer males, containing active I factors. The vermilion marked IviP2 element was designed to allow easy phenotypical screening for retrotransposition events. It is deleted in ORF2 and therefore cannot produce reverse transcriptase. IviP2 can be mobilized at very low frequencies by actively transposing I factors in the germ line of SF females. This paper shows that IviP2 can be mobilized more efficiently in the germ line of strongly reactive females in the absence of active I factors, when it is trans-complemented by the product of ORF2 synthesized from the hsp70 heat-shock promoter. This represents a promising step toward the use of marked I elements to study retrotransposition and as tools for mutagenesis.


1968 ◽  
Vol 7 (49) ◽  
pp. 89-94 ◽  
Author(s):  
M. E. R. Walford

AbstractField measurements are presented of dielectric absorption in Antarctic snow and ice at frequencies of a few hundred megahertz. They are compared with measurements by other authors at very high frequencies. The dielectric absorption in ice at these frequencies is accounted for in terms of absorption bands both at radio frequencies and in the infrared. Bands at radio frequencies are caused by a relaxation mechanism which depends upon the temperature and the impurity content of the ice. These two factors are therefore included in an account of the dielectric absorption in ice at very high frequencies.


2019 ◽  
Vol 116 (16) ◽  
pp. 7873-7878 ◽  
Author(s):  
Rafael Tapia-Rojo ◽  
Edward C. Eckels ◽  
Julio M. Fernández

Magnetic tape heads are ubiquitously used to read and record on magnetic tapes in technologies as diverse as old VHS tapes, modern hard-drive disks, or magnetic bands on credit cards. Their design highlights the ability to convert electric signals into fluctuations of the magnetic field at very high frequencies, which is essential for the high-density storage demanded nowadays. Here, we twist this conventional use of tape heads to implement one in a magnetic tweezers design, which offers the unique capability of changing the force with a bandwidth of ∼10 kHz. We calibrate our instrument by developing an analytical expression that predicts the magnetic force acting on a superparamagnetic bead based on the Karlqvist approximation of the magnetic field created by a tape head. This theory is validated by measuring the force dependence of protein L unfolding/folding step sizes and the folding properties of the R3 talin domain. We demonstrate the potential of our instrument by carrying out millisecond-long quenches to capture the formation of the ephemeral molten globule state in protein L, which has never been observed before. Our instrument provides the capability of interrogating individual molecules under fast-changing forces with a control and resolution below a fraction of a piconewton, opening a range of force spectroscopy protocols to study protein dynamics under force.


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