scholarly journals Diabetes mellitus type 1 in children and adolescents in Moscow. Data from the Moscow Segment of the Federal Register of Diabetic Patients 2015–2020

2021 ◽  
Vol 67 (6) ◽  
pp. 113-123
Author(s):  
E. E. Petryaykina ◽  
D. N. Laptev ◽  
I. G. Vorontsova ◽  
N. A. Demidov ◽  
Yu. А. Ryapolova

BACKGROUND: Therapy for type 1 diabetes mellitus (T1DM) is still largely an unsolved clinical problem. Despite the introduction into clinical practice of modern insulin preparations, devices for its administration, as well as continuous monitoring of glucose levels, the goals of therapy are often not achieved. At the same time, the International Diabetes Federation (IDF) notes an increase in the prevalence and incidence of T1DM in children and adolescents in the world. The Federal Register of Diabetes Mellitus (FRDM) is a dynamically updated database of patients with diabetes, which allows assessing prevalence and incidence rates, achievement of glycemic control goals and the incidence of diabetes complications.AIM: analyze the epidemiological data of T1DM (prevalence, morbidity) in children and adolescents (patients from birth to 18 years of age) in Moscow according to the FRSD data and to assess their dynamics, as well as the dynamics of achieving the goals of glycemic control and the incidence of T1DM complications in 2015-2020.MATERIALS AND METHODS: The object of the study is a sample from the database of the Moscow segment of the FRDM of a cohort of patients with type 1 diabetes under 18 years of age who were registered for the period 01.01.2015-01.01.2021. Epidemiological prevalence and incidence rates are calculated per 100,000 of the relevant population.RESULTS: the number of children and adolescents with type 1 diabetes in Moscow as of 01.01.2021 was 4024 people (2962 children and 1062 adolescents). Over the period from 2015 to 2020, there was an increase in the prevalence of T1DM (possibly due to an increase in the quality of data registration in the FRSD) and a decrease in the incidence of both children and adolescents. There was also a decrease in the level of HbA1c and the proportion of patients with HbAc1> 8.0% among children with T1DM. Both children and adolescents with T1DM showed a decrease in the incidence of diabetic coma and ketoacidosis with a simultaneous increase in the incidence of severe hypoglycemia, as well as a decrease in the incidence of retinopathy and nephropathy. However, the incidence of neuropathy decreased among children and increased among adolescents.CONCLUSION: The data obtained on the dynamic management of adolescents with T1DM are the basis for considering the development of a profile program for their dynamic observation, taking into account the need for psychological and social support for patients and their families.


2017 ◽  
Vol 31 (6) ◽  
pp. 1198-1203 ◽  
Author(s):  
Margarita Archinkova ◽  
Maia Konstantinova ◽  
Radka Savova ◽  
Violeta Iotova ◽  
Chayka Petrova ◽  
...  


2019 ◽  
Vol 154 ◽  
pp. 138-145
Author(s):  
Roberta Ferreira Fortins ◽  
Elisa Maria de Aquino Lacerda ◽  
Raquel Nascimento Chanca Silverio ◽  
Cleber Nascimento do Carmo ◽  
Aline Alves Ferreira ◽  
...  


2017 ◽  
Vol 126 ◽  
pp. 10-15 ◽  
Author(s):  
Asma Deeb ◽  
Nabras Al Qahtani ◽  
Mariette Akle ◽  
Himanshi Singh ◽  
Rifah Assadi ◽  
...  


2007 ◽  
Vol 50 (6) ◽  
pp. 565 ◽  
Author(s):  
Young Jun Rhie ◽  
Hyun Wook Chae ◽  
Ho Seong Kim ◽  
Duk Hee Kim


2020 ◽  
Vol 33 ◽  
Author(s):  
Camilla Kapp FRITZ ◽  
Andreia Araújo Porchat de LEÃO ◽  
Márcia Regina Messaggi Gomes DIAS ◽  
Adriane de Andre Cardoso DEMARTINI ◽  
Suzana NESI-FRANÇA

ABSTRACT Objective To review the dietary intake of children and adolescents with type 1 diabetes Mellitus and its association with the glycemic profile. Methods Longitudinal observational study. Dietary intake was measured using a three-day dietary record and the glycemic profile with a continuous glucose monitoring (range between 70 and 180mg/dL) and serum glycated hemoglobin levels (ideal <7.5%). Anthropometric data, insulin therapy, and carbohydrate counting were collected. Results The sample included 34 individuals with type 1 diabetes Mellitus aged 13.6±2.1 years. The majority of the population was eutrophic (76.4%). The entire sample used the basal-bolus insulin regimen, with mean insulin dose of 1.0±0.2U/kg/day; for 44.1% of the sample the carbohydrate counting method was used. Macronutrients intake was adequate in only 8.8% of the individuals, the highest frequency of inadequacy was related to carbohydrates (p=0.07). Inadequate glycemic control with hyperglycemia episodes and high mean glycated hemoglobin (9.7%) was observed in all individuals (61.3±18.5%). Carbohydrate counting was responsible for maintaining the percentage of time that the patient had interstitial blood glucose values within the range >40% (p<0.001) and maintaining the percentage of time in hyperglycemia <50% (p<0.001). Conclusion The majority of individuals were eutrophic, but presented inadequate dietary intake and glycemic control. The method of counting carbohydrates positively influenced the glycemic profile.



2018 ◽  
Vol 20 (6) ◽  
pp. 420-426 ◽  
Author(s):  
Dmitry N. Laptev ◽  
Valentina A. Peterkova

Rationale: Healthcare access plays a significant role in the improvement and maintaining of glycemic control and quality of life in type 1 diabetes mellitus (T1DM) patients on continuous subcutaneous insulin infusion (CSII). Aims: The aim of the study was to evaluate the feasibility of remote support in children and adolescents with type 1 diabetes mellitus (T1DM) and its effect on glycemic control and quality of life. Materials and methods: In 40 children and adolescents (132,7 years, 18/22 m/f) on CSII with inadequately controlled T1DM (HbA1c7,5%) we evaluated the effectiveness of telemedical support (TS), as compared with conventional support (CS). Parameters of glycemic control (HbA1c, average glycemia, SD, etc.) and quality of a life were obtained on follow-up visits. Patients and their parents in ТМ group twice a month sent their insulin pump data using to CSII center and diabetologists sent back their advice via e-mail, phone or Skype. The primary end point was the change from the baseline HbA1c level and the proportion of patients achieving HbA1c of less than 7.5%. Results: At 24 weeks, the baseline mean HbA1c (8.7% in the two study groups) had decreased to 7.7% in the TS group, as compared with 8.4% in the CS group (P0,05). The proportion of patients who reached the HbA1c target (7,5%) was greater in the TS group (50%) than in the CS group (20%, p0,05). A number of quality of life indicators for both parents and children with T1DM at the end of the study compared to baseline significantly increased in the TS group compared with the TC group (p0.05). During the study period rate of severe hypoglycemia and DKA in TS group (0 and 10 cases per 100 person-years) did not differ significantly from that in CS group (0 and 20 cases per 100 person-years, P0,05). Conclusion: In children with inadequately controlled T1DM, telemedical support proved to be feasible and resulted in significant improvement in glucose control (HbA1c, glucose variability) and quality of life without the increase in the incidence of DKA and severe glycemia.



Author(s):  
Mahin Hashemipour ◽  
Silva Hovsepian ◽  
Nafiseh Mozafarian ◽  
Zohreh Motaghi ◽  
Elahe Izadikhah ◽  
...  


2005 ◽  
Vol 6 (4) ◽  
pp. 206-212 ◽  
Author(s):  
Raphael Del Roio Liberatore ◽  
Sonia FC Barbosa ◽  
Maria das Gracas Alkimin ◽  
Raquel Bellinati-Pires ◽  
Marlene PC Florido ◽  
...  


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