scholarly journals Prevention of diabetes mellitus: past, present, and future

2009 ◽  
Vol 55 (2) ◽  
pp. 3-9
Author(s):  
E V Titovich

The incidence of type 1 diabetes mellitus (T1DM) is increasing in many countries of the world, the average annual increase in the frequency of the disease in European children is 3.4% at the age of 0-14 and 6.3% at the age of 0-5. The increase in the incidence of type 1 diabetes at an early age has a definite effect on the whole society as a whole, increasing the burden both on the patients themselves and their families, in particular, leading to an earlier development of complications. Since these changes in the development of diabetes have occurred too quickly to be due to changes at the genetic level, they are most likely a consequence of environmental changes.

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 2832-2838
Author(s):  
Faizal Achmad Hidayat ◽  
Herwienda Fatmayoni ◽  
Stefani Ayuningtyas ◽  
Anggi Muhtar Pratama

Type 1 diabetes mellitus is one of the most common degenerative diseases in the world. Out of 463 million diabetes mellitus patients in the world, 10% of them are type 1 diabetes mellitus patients. One of the complication causes and severity of type 1 diabetes mellitus is oxidative stress. Oxidative stress occurs due to the build-up of excess free radicals obtained from the metabolism of glucose and lipids. Free radicals that cause oxidative stress can be minimized with antioxidants. Beetroot (Beta vulgaris L.) is a plant that is rich in antioxidants and can be used as an alternative therapy for type 1 diabetes mellitus. Various flavonoid contents in beetroot extracts include quercetin, rutin, apigenin, kaempferol, and ferulic acid compounds that have antioxidant and antidiabetic activity. With the evolve of nanoparticle technology, it can be used to increase the solubility of drugs in water, to increase the duration of the drug in the systemic circulation, and to make drug release occurs gradually. The properties of this nanoparticle extract are indispensable for the efficacy and efficiency of treatment. The results of this study provide a lot of information and innovation for the development of the use of beetroot and the treatment of type 1 diabetes mellitus.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Asirvatham Alwin Robert ◽  
Abdulrahman Al-Dawish ◽  
Muhammad Mujammami ◽  
Mohamed Abdulaziz Al Dawish

Type 1 diabetes mellitus (T1DM) is quite prevalent in the world, with a proportion of 1 in every 300 persons and steadily rising frequency of incidence of about 3% every year. More alarmingly, the incidence of T1DM among infants is also increasing, with children as young as 6 months succumbing to it, instead of that at a rather established vulnerable age of around seven and near puberty, when the hormones antagonize the action of insulin. These reports pose a unique challenge of developing efficient T1DM management system for the young children. The Kingdom of Saudi Arabia (KSA) is the largest country in the Middle East that occupies approximately four-fifths of the Arabian Peninsula supporting a population of more than 33.3 million people, of whom 26% are under the age of 14 years. As per the Diabetes Atlas (8th edition), 35,000 children and adolescents in Saudi Arabia suffer from T1DM, which makes Saudi Arabia rank the 8th in terms of numbers of TIDM patients and 4th country in the world in terms of the incidence rate (33.5 per 100,000 individuals) of TIDM. However, in comparison with that in the developed countries, the number of research interventions on the prevalence, incidence, and the sociodemographic aspects of T1DM is woefully inadequate. In this review we discuss different aspects of T1DM in Saudi Arabia drawing on the published literature currently available.


Author(s):  
Narbaev Abduhamid Namazovich ◽  
Togaeva Gulnora Siddiqovna ◽  
Davranova Aziza Davranovna

Type 1 diabetes mellitus is a disease in which the highest rates of premature mortality and early disability of patients are observed, which is caused by the onset of the disease at an early age, the instability of the course of type 1 diabetes and the threat of acute and chronic complications.  The goals of type 1 diabetes mellitus treatment are its compensation, prevention of the risk of complications when normoglycemia is reached and stabilized.


2013 ◽  
Author(s):  
Blake M. Lancaster ◽  
Ashley M. Lugo ◽  
Lynne Clure ◽  
Kate S. Holman ◽  
Ryan T. Thorson

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