scholarly journals The cardiovascular system in patients with symptomatic and mild primary hyperparathyroidism

2009 ◽  
Vol 55 (3) ◽  
pp. 25-29 ◽  
Author(s):  
I V Voronenko ◽  
N G Mokrysheva ◽  
L Ya Rozhinskaya ◽  
A L Syrkin
Keyword(s):  
Parathyroid Hormone ◽  
Left Ventricular Hypertrophy ◽  
Primary Hyperparathyroidism ◽  
Cardiovascular System ◽  
Qt Interval ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ionized Calcium ◽  
Mild Primary Hyperparathyroidism

The cardiovascular system was analyzed in patients with symptomatic (n = 31) and mild primary hyperparathyroidism (n = 34) whose mean age was 54.6 years; 95% females). In the patients with symptomatic primary hyperparathyroidism, the PQ interval was longer and the QT interval was significantly shorter than those in patients with mild hyperparathyroidism. Left ventricular hypertrophy was noted in 45.2% of patients with symptomatic and in 15.2% of those with mild hyperparathyroidism (p = 0.013). Left ventricular diastolic dysfunction was also more common in the group of symptomatic hyperparathyroidism. There was a statistically significant correlation between the levels of parathyroid hormone, total and ionized calcium and the duration of QT interval and the determinants of diastolic function and left ventricular hypertrophy. The revealed cardiovascular disorders in patients with primary hyperparathyroidism are presumed to depend on the increase rate of parathyroid hormone and total and ionized calcium.

scholarly journals Association of Arterial Stiffness and Electrocardiography-Determined Left Ventricular Hypertrophy with Left Ventricular Diastolic Dysfunction

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e49100 ◽  
Author(s):  
Po-Chao Hsu ◽  
Wei-Chung Tsai ◽  
Tsung-Hsien Lin ◽  
Ho-Ming Su ◽  
Wen-Chol Voon ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Left Ventricular Hypertrophy ◽  
Diastolic Dysfunction ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ventricular Diastolic Dysfunction

Prolongation of the QT interval in heart failure occurs at low but not at high heart rates

2000 ◽  
Vol 98 (5) ◽  
pp. 603-610 ◽  
Author(s):  
P. P. DAVEY ◽  
C. BARLOW ◽  
G. HART
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Left Ventricular Hypertrophy ◽  
Qt Interval ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Qt Interval Prolongation ◽  
Qt Intervals ◽  
Ventricular Structure ◽  
And Function

Abnormal left ventricular structure and function as in, for example, left ventricular hypertrophy or chronic heart failure, is associated with sudden cardiac death and, when the ejection fraction is depressed, with prolongation of the QT interval. The dependence on heart rate of QT interval prolongation in these conditions, and the relationship of any abnormalities either to deranged autonomic nervous system function or to an adverse prognosis, has not been well studied. We therefore investigated (1) the dependence on heart rate of the QT interval, and (2) the relationship between both QT interval and the QT/heart rate slope and markers of adverse prognosis in these two conditions. The QT interval was measured at rest and during exercise in 34 subjects with heart failure, 16 subjects with left ventricular hypertrophy and 16 age-matched controls with normal left ventricular structure and function. QTc (corrected QT) intervals at rest were significantly longer in heart failure patients (471±10 ms) than in controls (421±6 ms) or in subjects with hypertrophy (420±6 ms) (P < 0.05). At peak exercise, despite the attainment of similar heart rates, the QT intervals no longer differed from each other, being 281±7 ms for controls, 296±11 ms in hypertrophy and 303±10 ms in heart failure (no significant difference). The QT/heart rate slope was significantly increased in heart failure [2.3±0.1 ms·(beats/min)-1] compared with controls [1.55±0.06 ms·(beats/min)-1] and hypertrophy [1.66±0.1 ms·(beats/min)-1] (P < 0.001). In left ventricular hypertrophy, despite animal data suggesting that QT interval prolongation should occur, no abnormalities were found in QT intervals at rest or during exercise. The QT/heart rate slope did not relate to any markers for an adverse prognosis, except that of prolongation of QT interval. Long QT intervals were associated principally with impairment of left ventricular systolic function. Our data emphasize the dynamic nature of the QT interval abnormalities found in heart failure.

scholarly journals Combined QT Interval and Voltage Criteria Improve Left Ventricular Hypertrophy Detection in Resistant Hypertension

Hypertension ◽  
2005 ◽  
Vol 46 (5) ◽  
pp. 1207-1212 ◽  
Author(s):  
Gil Salles ◽  
Sharon Leocádio ◽  
Katia Bloch ◽  
Armando R. Nogueira ◽  
Elizabeth Muxfeldt
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Resistant Hypertension ◽  
Qt Interval ◽  
Ventricular Hypertrophy ◽  
Left Ventricular

Effect of telmisartan on QT interval variability and autonomic control in hypertensive patients with left ventricular hypertrophy

2010 ◽  
Vol 64 (8) ◽  
pp. 516-520 ◽  
Author(s):  
Fabio Galetta ◽  
Ferdinando Franzoni ◽  
Poupak Fallahi ◽  
Leonardo Tocchini ◽  
Francesca Graci ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Qt Interval ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Autonomic Control ◽  
Hypertensive Patients ◽  
Qt Interval Variability

Relation of QT interval and QT dispersion to echocardiographic left ventricular hypertrophy and geometric pattern in hypertensive patients. The LIFE study.

2001 ◽  
Vol 19 (10) ◽  
pp. 1883-1891 ◽  
Author(s):  
Lasse Oikarinen ◽  
Markku S. Nieminen ◽  
Matti Viitasalo ◽  
Lauri Toivonen ◽  
Kristian Wachtell ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Qt Interval ◽  
Ventricular Hypertrophy ◽  
Qt Dispersion ◽  
Left Ventricular ◽  
Geometric Pattern ◽  
Hypertensive Patients ◽  
Life Study

Left ventricular hypertrophy and QT interval in obesity and in hypertension: effects of weight loss and of normalisation of blood pressure

2004 ◽  
Vol 28 (9) ◽  
pp. 1118-1123 ◽  
Author(s):  
A E Pontiroli ◽  
P Pizzocri ◽  
A Saibene ◽  
A Girola ◽  
D Koprivec ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Weight Loss ◽  
Left Ventricular Hypertrophy ◽  
Qt Interval ◽  
Ventricular Hypertrophy ◽  
Left Ventricular
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