PO-118 Effects of field-battle hypoxia supporter on free radical metabolism after exercise at high altitude

Objective To explore the effects of field-battle hypoxia supporter on free radical metabolism after exercise at high altitude． Methods A total of 40 healthy fighters stationed in the 3800m plateau for 10 days were randomly divided into two groups. Each group of 20 men, armed with heavy weapons and hypoxia supporter, hiked 5 km and then climbed a 4,300 m peak, a total distance of 10 km. The control group closed the valve of hypoxia supporter without oxygen inhalation, the experimental group opened the valve and inhaled oxygen. The serum levels of superoxide dismutase(SOD), total antioxidant capacity(T-AOC), reactive oxygen species (ROS) and malondialdehyde (MDA) were measured at rest and after exercise. In addition, The average marching speed of the two groups were compared． Results The T-AOC, ROS and MDA were increased both in the control group and experimental group after exercise, and the SOD increased significanly in experimental group (P<0.01)．Compared with control group, the SOD and T-AOC were increase but the ROS and MDA were decreased significanly after exercise(P<0.01)．The average speed of 10km cross-country march in the control group and the experimental group was (3.0±0.3)km/h and (2.3±0.5)km/h respectively, and there were significant differences (P<0.01). Conclusions The field-battle hypoxia supporter can restrain free radical damage after exercise at high altitude and increase the efficiency of work at high altitude. Acknowledgements: This work was supported by the Guangdong Science and Technology Equipment Mobilization project (Research and application of field-battle hypoxia supporter).

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Study of antioxidant potential in leaves, stems, nuts of Juglans regia L.

International Journal of Bioassays ◽

10.21746/ijbio.2012.10.003 ◽

2012 ◽

Vol 1 (10) ◽

pp. 79 ◽

Cited By ~ 2

Author(s):

G. Raja* ◽

Ivvala Anand Shaker ◽

Inampudi Sailaja ◽

R. Swaminathan ◽

S. Saleem Basha ◽

...

Keyword(s):

Free Radicals ◽

Free Radical ◽

Antioxidant Activities ◽

Radical Scavenging Activity ◽

Juglans Regia ◽

Radical Scavenging ◽

Antioxidant Compounds ◽

Free Radical Damage ◽

Radical Damage

Natural antioxidants can protect the human body from free radicals and retard the progress of many chronic diseases as well as lipid oxidative rancidity in foods. The role of antioxidants has protected effect against free radical damage that may cause many diseases including cancer. Primary sources of naturally occurring antioxidants are known as whole grains, fruits, and vegetables. Several studies suggest that regular consumption of nuts, mostly walnuts, may have beneficial effects against oxidative stress mediated diseases such as cardiovascular disease and cancer. The role of antioxidants has attracted much interest with respect to their protective effect against free radical damage that may cause many diseases including cancer. Juglans regia L. (walnut) contains antioxidant compounds, which are thought to contribute to their biological properties. Polyphenols, flavonoids and flavonols concentrations and antioxidant activity of Leaves, Stems and Nuts extract of Juglans regia L. as evaluated using DPPH, ABTS, Nitric acid, hydroxyl and superoxide radical scavenging activity, lipid peroxidation and total oxidation activity were determined. The antioxidant activities of Leaves, Stems and Nuts extract of Juglans regia L. were concentration dependent in different experimental models and it was observed that free radicals were scavenged by the test compounds in all the models.

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