COVID, Disablement, and the "Return to Normal"

2021 ◽  
pp. 29-35
Author(s):  
Keith Rosenthal ◽  
Ari Parra

For many disabled people, the "abnormal" state of things over the last year and a half is not such an estranged discontinuity from the previous state of things. Certainly, just like everyone, pandemic life for disabled people has been exceedingly difficult, painful, oppressive, and deadly. But the "normal" of pre-pandemic life was also exceedingly difficult, painful, oppressive, and deadly.

2011 ◽  
Author(s):  
Sangyeon Yoon ◽  
Seungah Ryu ◽  
Shinhwa Suh ◽  
Yonghun Kim

2019 ◽  
Author(s):  
Wengong Jin ◽  
Regina Barzilay ◽  
Tommi S Jaakkola

The problem of accelerating drug discovery relies heavily on automatic tools to optimize precursor molecules to afford them with better biochemical properties. Our work in this paper substantially extends prior state-of-the-art on graph-to-graph translation methods for molecular optimization. In particular, we realize coherent multi-resolution representations by interweaving trees over substructures with the atom-level encoding of the original molecular graph. Moreover, our graph decoder is fully autoregressive, and interleaves each step of adding a new substructure with the process of resolving its connectivity to the emerging molecule. We evaluate our model on multiple molecular optimization tasks and show that our model outperforms previous state-of-the-art baselines by a large margin.


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